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The map label for this gene is fadE35 [H]

Identifier: 54025795

GI number: 54025795

Start: 4043763

End: 4044908

Strand: Reverse

Name: fadE35 [H]

Synonym: nfa38250

Alternate gene names: 54025795

Gene position: 4044908-4043763 (Counterclockwise)

Preceding gene: 54025796

Following gene: 54025791

Centisome position: 67.18

GC content: 65.62

Gene sequence:

>1146_bases
GTGGAGCGCACACTGTTCGAGCCCGAGCACGAGTTGTTCCGGGAGTCGTACCGCAAGTTTCTCGATCAGCACGTCGCCCC
GAACCACGCGAAGTGGGAAGAGGCGGGCATCGTCGATCGTGACGTGTGGCTCGAGGCCGGCAAGCAGGGTTTCCTCGGCA
TGGCTGTGCCCGAGGAATTCGGCGGCGGCGGCGTCAAGGACTTCCGCTACAACGCCGTGATCACCGAGGAGACCGTCAAG
GGGCAGTACTCCGGTCTGGGTTTCTCGCTGCACAACGACGTCATCGCGCCGTACCTGCTCGAGCTGTCCAACGACGAGCA
GAAGCAGCGCTGGTTGCCCAAGTTCTGCTCCGGTGAGCTGATCACCGCCATCGCCATGACCGAGCCCGGCACCGGCTCGG
ATCTGCAGGGCATCAAGACCCGCGCGGTGCGCGACGGCGACGACTGGATCCTCAACGGCGCCAAGACCTTCATCACCAAC
GGCATCAACGCCGACCTCGTGATCGTGGTCGCCCAGACCGACCCGGAGAAGGGCGCGATGGGCTTCAGCCTGCTCGTCGT
CGAGCGCGGCATGCCCGGCTTCGAGCGCGGCCGCAACCTCGACAAGATCGGTCTCAAGGCGCAGGACACCGCCGAGCTGA
GCTTCACCGACGTCCGCGTGCCCGGCAAGAACCTGCTCGGCACCGAGGGCATGGGCTTCATCCACCTGATGCAGAACCTG
CCCCAGGAACGCATGTCCATCGCCGTCATGGCGGCCGCCGCGATGGAGGCGTGCCTGGACATGACCTGTCAGTACGTGCG
CGACCGCAAGGCGTTCGGCAAGCCGATCGGCGCCCTGCAGAACACCCGGTTCGTGCTGGCCGAGCTGGCCACCAAGACCA
CCGCGGTGCGGATCATGGTCGACCGCTTCATCGAGGACCTCAACGCGGGCAAGCTCTCCGCCGAGGACGCCGCGATGGCC
AAGTGGTGGAGCACCGAGGAGCAGCTCGACCTCATCAACCGGTGCCTGCAGCTGCACGGCGGCTACGGCTACATGCGCGA
GTACCCCATCGCCAAGGCCTACACCGATGCCCGCATCCAGACGATCTACGGCGGCACCACCGAGATCATGAAGGAGATCA
TCGGCCGCTCCCTCAAACTCACCTGA

Upstream 100 bases:

>100_bases
GATTTTCCGGTGCGAAGTGAACTGTGATTCGTGTTCCGGGTACCGTATGCGGTAACGACGGGTCGGTTGGTCCGGCCGGT
GTGGTCACTAGGAGGTTGGT

Downstream 100 bases:

>100_bases
TCCCACCCTTTTTCGATGCCGGACGGGTGCTCGACCCGTCCGGCATCGTCGTCTCCGGGCACTACGGAATGCAGACGACC
GGCGCGGTATCCGACAGGGA

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MERTLFEPEHELFRESYRKFLDQHVAPNHAKWEEAGIVDRDVWLEAGKQGFLGMAVPEEFGGGGVKDFRYNAVITEETVK
GQYSGLGFSLHNDVIAPYLLELSNDEQKQRWLPKFCSGELITAIAMTEPGTGSDLQGIKTRAVRDGDDWILNGAKTFITN
GINADLVIVVAQTDPEKGAMGFSLLVVERGMPGFERGRNLDKIGLKAQDTAELSFTDVRVPGKNLLGTEGMGFIHLMQNL
PQERMSIAVMAAAAMEACLDMTCQYVRDRKAFGKPIGALQNTRFVLAELATKTTAVRIMVDRFIEDLNAGKLSAEDAAMA
KWWSTEEQLDLINRCLQLHGGYGYMREYPIAKAYTDARIQTIYGGTTEIMKEIIGRSLKLT

Sequences:

>Translated_381_residues
MERTLFEPEHELFRESYRKFLDQHVAPNHAKWEEAGIVDRDVWLEAGKQGFLGMAVPEEFGGGGVKDFRYNAVITEETVK
GQYSGLGFSLHNDVIAPYLLELSNDEQKQRWLPKFCSGELITAIAMTEPGTGSDLQGIKTRAVRDGDDWILNGAKTFITN
GINADLVIVVAQTDPEKGAMGFSLLVVERGMPGFERGRNLDKIGLKAQDTAELSFTDVRVPGKNLLGTEGMGFIHLMQNL
PQERMSIAVMAAAAMEACLDMTCQYVRDRKAFGKPIGALQNTRFVLAELATKTTAVRIMVDRFIEDLNAGKLSAEDAAMA
KWWSTEEQLDLINRCLQLHGGYGYMREYPIAKAYTDARIQTIYGGTTEIMKEIIGRSLKLT
>Mature_381_residues
MERTLFEPEHELFRESYRKFLDQHVAPNHAKWEEAGIVDRDVWLEAGKQGFLGMAVPEEFGGGGVKDFRYNAVITEETVK
GQYSGLGFSLHNDVIAPYLLELSNDEQKQRWLPKFCSGELITAIAMTEPGTGSDLQGIKTRAVRDGDDWILNGAKTFITN
GINADLVIVVAQTDPEKGAMGFSLLVVERGMPGFERGRNLDKIGLKAQDTAELSFTDVRVPGKNLLGTEGMGFIHLMQNL
PQERMSIAVMAAAAMEACLDMTCQYVRDRKAFGKPIGALQNTRFVLAELATKTTAVRIMVDRFIEDLNAGKLSAEDAAMA
KWWSTEEQLDLINRCLQLHGGYGYMREYPIAKAYTDARIQTIYGGTTEIMKEIIGRSLKLT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=51.3227513227513, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=34.4, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=35.0877192982456, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=35.656836461126, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=33.8709677419355, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=31.8181818181818, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=31.7333333333333, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=31.7333333333333, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=31.7948717948718, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI4557235, Length=390, Percent_Identity=31.7948717948718, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI21361497, Length=366, Percent_Identity=30.6010928961749, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI4503943, Length=372, Percent_Identity=28.494623655914, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI7669494, Length=346, Percent_Identity=28.6127167630058, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI48976061, Length=404, Percent_Identity=26.4851485148515, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI211971008, Length=404, Percent_Identity=26.4851485148515, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI38505218, Length=378, Percent_Identity=24.3386243386243, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=29.1338582677165, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1786223, Length=262, Percent_Identity=26.7175572519084, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87082384, Length=282, Percent_Identity=25.531914893617, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081702, Length=355, Percent_Identity=22.5352112676056, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=35.6756756756757, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17538396, Length=368, Percent_Identity=33.1521739130435, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17534899, Length=364, Percent_Identity=33.7912087912088, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=32.5459317585302, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=32.6259946949602, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=29.6398891966759, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17505929, Length=380, Percent_Identity=32.6315789473684, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17551932, Length=381, Percent_Identity=31.496062992126, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=30.3523035230352, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=32.7338129496403, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=356, Percent_Identity=32.5842696629214, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71985192, Length=291, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71982178, Length=269, Percent_Identity=30.4832713754647, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32563615, Length=223, Percent_Identity=32.2869955156951, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=27.8947368421053, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=28.4518828451883, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=28.0276816608997, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=33.7837837837838, Blast_Score=221, Evalue=6e-58,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=33.245382585752, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=31.2997347480106, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=32.4324324324324, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=30.0813008130081, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281363737, Length=333, Percent_Identity=31.2312312312312, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI19920834, Length=384, Percent_Identity=30.2083333333333, Blast_Score=138, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42387; Mature: 42387

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTLFEPEHELFRESYRKFLDQHVAPNHAKWEEAGIVDRDVWLEAGKQGFLGMAVPEEF
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHCCCCCCEEEECCHHH
GGGGVKDFRYNAVITEETVKGQYSGLGFSLHNDVIAPYLLELSNDEQKQRWLPKFCSGEL
CCCCCCCEEEEEEEEHHHHCCHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHCHHHCCCCE
ITAIAMTEPGTGSDLQGIKTRAVRDGDDWILNGAKTFITNGINADLVIVVAQTDPEKGAM
EEEEEECCCCCCCCCCHHHHHHCCCCCCEEECCCHHHHCCCCCCCEEEEEEECCCCCCCC
GFSLLVVERGMPGFERGRNLDKIGLKAQDTAELSFTDVRVPGKNLLGTEGMGFIHLMQNL
CEEEEEEECCCCHHHHCCCCHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHC
PQERMSIAVMAAAAMEACLDMTCQYVRDRKAFGKPIGALQNTRFVLAELATKTTAVRIMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHH
DRFIEDLNAGKLSAEDAAMAKWWSTEEQLDLINRCLQLHGGYGYMREYPIAKAYTDARIQ
HHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCCCEEE
TIYGGTTEIMKEIIGRSLKLT
EEECCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERTLFEPEHELFRESYRKFLDQHVAPNHAKWEEAGIVDRDVWLEAGKQGFLGMAVPEEF
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHCCCCCCEEEECCHHH
GGGGVKDFRYNAVITEETVKGQYSGLGFSLHNDVIAPYLLELSNDEQKQRWLPKFCSGEL
CCCCCCCEEEEEEEEHHHHCCHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHCHHHCCCCE
ITAIAMTEPGTGSDLQGIKTRAVRDGDDWILNGAKTFITNGINADLVIVVAQTDPEKGAM
EEEEEECCCCCCCCCCHHHHHHCCCCCCEEECCCHHHHCCCCCCCEEEEEEECCCCCCCC
GFSLLVVERGMPGFERGRNLDKIGLKAQDTAELSFTDVRVPGKNLLGTEGMGFIHLMQNL
CEEEEEEECCCCHHHHCCCCHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHC
PQERMSIAVMAAAAMEACLDMTCQYVRDRKAFGKPIGALQNTRFVLAELATKTTAVRIMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHH
DRFIEDLNAGKLSAEDAAMAKWWSTEEQLDLINRCLQLHGGYGYMREYPIAKAYTDARIQ
HHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCCCEEE
TIYGGTTEIMKEIIGRSLKLT
EEECCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]