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The map label for this gene is pmsR

Identifier: 54020572

GI number: 54020572

Start: 690805

End: 691233

Strand: Reverse

Name: pmsR

Synonym: mhp546

Alternate gene names: 54020572

Gene position: 691233-690805 (Counterclockwise)

Preceding gene: 54020573

Following gene: 54020571

Centisome position: 77.43

GC content: 31.93

Gene sequence:

>429_bases
ATGAAAAAAGAAAAAAAATTAGACCATTTAACAGAATTGCAATACAAGGTAACTCAGCAAAATTTTACTGAGCCTGCCTT
TGATAATCTTTATAATAATAATTATCAAGAAGGAGTTTATGTTGATATTGTAGATGGAACTCCACTTTTTTTATCAATAT
ATAAATATGACTCAGGTTCAGGTTGGCCATCTTTTTCAAAACCAATTGATGAAAATTTAATAGTGGAGGTTCTGGATTTT
AGTGCCTCGCTAACTCGAATCGAAGTGCGTTCAAAAAACGCTGATTCGCATTTAGGTCATGTTTTTAGCGATGGTCCAAA
ACAATTTGGGGGGAGGCGCTACTGTATTAATTCAGCATCGCTTAAATTTATTCCTAAATCTGAACTAAAATCACATAATT
TAGGTCATCTTTTAGAGTTCTTTAAATAA

Upstream 100 bases:

>100_bases
TGATCAGCAAATAGTATATTACTAAAATTTTTTTGATCTTAAATTTTTTAAAAAACCCTTAAATTTATAGCATAATTTAT
TTTTTACAAAAAGAAATACT

Downstream 100 bases:

>100_bases
AGATATAAAATAATTTTTTTAAAATACAAAAAAGTTGTGGTATAATTTATTTATTCATTCTGTTTTTCAGTTTCATTTTT
ACTGATCAAACTAACTGCGG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MKKEKKLDHLTELQYKVTQQNFTEPAFDNLYNNNYQEGVYVDIVDGTPLFLSIYKYDSGSGWPSFSKPIDENLIVEVLDF
SASLTRIEVRSKNADSHLGHVFSDGPKQFGGRRYCINSASLKFIPKSELKSHNLGHLLEFFK

Sequences:

>Translated_142_residues
MKKEKKLDHLTELQYKVTQQNFTEPAFDNLYNNNYQEGVYVDIVDGTPLFLSIYKYDSGSGWPSFSKPIDENLIVEVLDF
SASLTRIEVRSKNADSHLGHVFSDGPKQFGGRRYCINSASLKFIPKSELKSHNLGHLLEFFK
>Mature_142_residues
MKKEKKLDHLTELQYKVTQQNFTEPAFDNLYNNNYQEGVYVDIVDGTPLFLSIYKYDSGSGWPSFSKPIDENLIVEVLDF
SASLTRIEVRSKNADSHLGHVFSDGPKQFGGRRYCINSASLKFIPKSELKSHNLGHLLEFFK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=116, Percent_Identity=50, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI301336162, Length=116, Percent_Identity=50, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI73089054, Length=116, Percent_Identity=50, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI37620216, Length=116, Percent_Identity=50, Blast_Score=119, Evalue=7e-28,
Organism=Homo sapiens, GI117606353, Length=124, Percent_Identity=45.9677419354839, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1788077, Length=115, Percent_Identity=51.304347826087, Blast_Score=122, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=113, Percent_Identity=42.4778761061947, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=113, Percent_Identity=42.4778761061947, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=121, Percent_Identity=34.7107438016529, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24645799, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221378664, Length=125, Percent_Identity=44.8, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221378662, Length=132, Percent_Identity=41.6666666666667, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645801, Length=136, Percent_Identity=41.9117647058824, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645804, Length=136, Percent_Identity=41.9117647058824, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16283; Mature: 16283

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEKKLDHLTELQYKVTQQNFTEPAFDNLYNNNYQEGVYVDIVDGTPLFLSIYKYDSGS
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCC
GWPSFSKPIDENLIVEVLDFSASLTRIEVRSKNADSHLGHVFSDGPKQFGGRRYCINSAS
CCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCHHHHCCEEEEECCCC
LKFIPKSELKSHNLGHLLEFFK
EEECCHHHHCCCCHHHHHHHCC
>Mature Secondary Structure
MKKEKKLDHLTELQYKVTQQNFTEPAFDNLYNNNYQEGVYVDIVDGTPLFLSIYKYDSGS
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCC
GWPSFSKPIDENLIVEVLDFSASLTRIEVRSKNADSHLGHVFSDGPKQFGGRRYCINSAS
CCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCHHHHCCEEEEECCCC
LKFIPKSELKSHNLGHLLEFFK
EEECCHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA