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The map label for this gene is dinB [H]

Identifier: 54019998

GI number: 54019998

Start: 58888

End: 60045

Strand: Direct

Name: dinB [H]

Synonym: mhp047

Alternate gene names: 54019998

Gene position: 58888-60045 (Clockwise)

Preceding gene: 54019997

Following gene: 54019999

Centisome position: 6.6

GC content: 24.18

Gene sequence:

>1158_bases
ATGTTAAAAATAATTGCTCATATTGATATTGATAACTTTTTTGTTTCATCAGAACTAAAGTTAAACCCAAAATTAAAAGG
ACAGCCAATTGTAATTTCCCGAAGCGAGGATTTTGCAATGGCTGTTTCTGTCTCTAAAGAGGTTAAGTCAAAAGGTTTCA
AAATATCAGATAAAATTAATGAAATTAAAAAAAAGATACCTAATTTATTAGTAATTCATCCAAATATAAATTATTATAAA
TTCTTATCTGATCAATTTTTTAATTTTATAAGTAAAAATTTTTCAAAAAAAATTGAGGTTTATTCAATTGATGAATGTTT
TATTGATCTAACAGAATATTCCCGAAAATTTAAGTCAATTACAGATATGCTCTATTTTATTAAAAATAAACTAGTAAAAA
ATTTTAGATTACCAATCTCAATCGGACTATCCTATAATAAATTATTAGCAAAAATGGCAACAAATTTAGCCAAAAATTCA
GAAGCAGGCATTATGCAGGTTTCAACAAAAAAAGATGTTAAAGCTTTTATTTATCCTCAAAAAATAGGCAATCTTTTCGG
AATTGGCATTCAAAATACTGAAAAATTAAAAAAATTTGGAATTATCACTATTCAAGATTTTATCCAAAAAGGTGTTAATA
ATGAGAAAATAATTGAAATTTTAGGAGTTAATCGTTATTATTTTTTTCATGCATTAACTAAAATAGGTGATGATAATGTT
TGTGATAAACTTGAAAAATTCAAGAGTGTTTCACATTTTCGCACTTTATCAGGAGATATTTTACTAACTAAAAAGCAAAT
CTTAGACGGTGTTTCCGAATTTTTACTAGAATTAGTAGAAAAACTAAGAAAATTCAACAAAGCAGCAAATCGTGTTGAAT
TTTTTTTTAAATTAAAAAATAAAGAAAAAGATCATTTTTTTTCTGATATAAGTTTCCCCTCAAATGATTATGATTTTCTT
TATCAGAATTTGCTAGCACTTGTTGAAAAAATTGAAAATTTTTCTTTAATTCACGGCTTTGGTATCACCCTATCAAAAAT
TTCAGATTATGATAAAAGTATGTTAAATACTAATCCAAAAGTAAAAAATATTGTTGCAAAAGTTAATAAAAAAATCGGGC
TGAAGAAATTATTTGTCCTAAAGTATCTTAAAAATTAA

Upstream 100 bases:

>100_bases
ATAAAAAACATATGTTAAATCGTAACTATAAAATTAGTTTATATCAGGATATTTAATATTAGTTATTTTCGAAAAATTAA
GTATAATTATTTTTGATTTT

Downstream 100 bases:

>100_bases
AAAAATGAAAAAACTTTTATATTTTTATTTAAAAATATTTTTTCTAATAGCAGTAGTTTTAGCTTTTGTTGCAGTTTGGA
ATTACACATTAATATTTGGA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLKIIAHIDIDNFFVSSELKLNPKLKGQPIVISRSEDFAMAVSVSKEVKSKGFKISDKINEIKKKIPNLLVIHPNINYYK
FLSDQFFNFISKNFSKKIEVYSIDECFIDLTEYSRKFKSITDMLYFIKNKLVKNFRLPISIGLSYNKLLAKMATNLAKNS
EAGIMQVSTKKDVKAFIYPQKIGNLFGIGIQNTEKLKKFGIITIQDFIQKGVNNEKIIEILGVNRYYFFHALTKIGDDNV
CDKLEKFKSVSHFRTLSGDILLTKKQILDGVSEFLLELVEKLRKFNKAANRVEFFFKLKNKEKDHFFSDISFPSNDYDFL
YQNLLALVEKIENFSLIHGFGITLSKISDYDKSMLNTNPKVKNIVAKVNKKIGLKKLFVLKYLKN

Sequences:

>Translated_385_residues
MLKIIAHIDIDNFFVSSELKLNPKLKGQPIVISRSEDFAMAVSVSKEVKSKGFKISDKINEIKKKIPNLLVIHPNINYYK
FLSDQFFNFISKNFSKKIEVYSIDECFIDLTEYSRKFKSITDMLYFIKNKLVKNFRLPISIGLSYNKLLAKMATNLAKNS
EAGIMQVSTKKDVKAFIYPQKIGNLFGIGIQNTEKLKKFGIITIQDFIQKGVNNEKIIEILGVNRYYFFHALTKIGDDNV
CDKLEKFKSVSHFRTLSGDILLTKKQILDGVSEFLLELVEKLRKFNKAANRVEFFFKLKNKEKDHFFSDISFPSNDYDFL
YQNLLALVEKIENFSLIHGFGITLSKISDYDKSMLNTNPKVKNIVAKVNKKIGLKKLFVLKYLKN
>Mature_385_residues
MLKIIAHIDIDNFFVSSELKLNPKLKGQPIVISRSEDFAMAVSVSKEVKSKGFKISDKINEIKKKIPNLLVIHPNINYYK
FLSDQFFNFISKNFSKKIEVYSIDECFIDLTEYSRKFKSITDMLYFIKNKLVKNFRLPISIGLSYNKLLAKMATNLAKNS
EAGIMQVSTKKDVKAFIYPQKIGNLFGIGIQNTEKLKKFGIITIQDFIQKGVNNEKIIEILGVNRYYFFHALTKIGDDNV
CDKLEKFKSVSHFRTLSGDILLTKKQILDGVSEFLLELVEKLRKFNKAANRVEFFFKLKNKEKDHFFSDISFPSNDYDFL
YQNLLALVEKIENFSLIHGFGITLSKISDYDKSMLNTNPKVKNIVAKVNKKIGLKKLFVLKYLKN

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=209, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786425, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19923006, Length=271, Percent_Identity=25.0922509225092, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44498; Mature: 44498

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIIAHIDIDNFFVSSELKLNPKLKGQPIVISRSEDFAMAVSVSKEVKSKGFKISDKIN
CEEEEEEECCCCEEEECCEEECCCCCCCCEEEECCCCCEEEEHHHHHHHHCCCCCHHHHH
EIKKKIPNLLVIHPNINYYKFLSDQFFNFISKNFSKKIEVYSIDECFIDLTEYSRKFKSI
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHH
TDMLYFIKNKLVKNFRLPISIGLSYNKLLAKMATNLAKNSEAGIMQVSTKKDVKAFIYPQ
HHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHEEECHH
KIGNLFGIGIQNTEKLKKFGIITIQDFIQKGVNNEKIIEILGVNRYYFFHALTKIGDDNV
HHCCEEECCCCCHHHHHHHCCEEHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCHH
CDKLEKFKSVSHFRTLSGDILLTKKQILDGVSEFLLELVEKLRKFNKAANRVEFFFKLKN
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
KEKDHFFSDISFPSNDYDFLYQNLLALVEKIENFSLIHGFGITLSKISDYDKSMLNTNPK
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCH
VKNIVAKVNKKIGLKKLFVLKYLKN
HHHHHHHHHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MLKIIAHIDIDNFFVSSELKLNPKLKGQPIVISRSEDFAMAVSVSKEVKSKGFKISDKIN
CEEEEEEECCCCEEEECCEEECCCCCCCCEEEECCCCCEEEEHHHHHHHHCCCCCHHHHH
EIKKKIPNLLVIHPNINYYKFLSDQFFNFISKNFSKKIEVYSIDECFIDLTEYSRKFKSI
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHH
TDMLYFIKNKLVKNFRLPISIGLSYNKLLAKMATNLAKNSEAGIMQVSTKKDVKAFIYPQ
HHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHEEECHH
KIGNLFGIGIQNTEKLKKFGIITIQDFIQKGVNNEKIIEILGVNRYYFFHALTKIGDDNV
HHCCEEECCCCCHHHHHHHCCEEHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCHH
CDKLEKFKSVSHFRTLSGDILLTKKQILDGVSEFLLELVEKLRKFNKAANRVEFFFKLKN
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
KEKDHFFSDISFPSNDYDFLYQNLLALVEKIENFSLIHGFGITLSKISDYDKSMLNTNPK
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCH
VKNIVAKVNKKIGLKKLFVLKYLKN
HHHHHHHHHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA