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The map label for this gene is gatA1 [H]

Identifier: 53723325

GI number: 53723325

Start: 3108024

End: 3109610

Strand: Reverse

Name: gatA1 [H]

Synonym: BPSS2307

Alternate gene names: 53723325

Gene position: 3109610-3108024 (Counterclockwise)

Preceding gene: 53723327

Following gene: 53723324

Centisome position: 98.0

GC content: 74.86

Gene sequence:

>1587_bases
ATGAAACGACGGCAATTCCTTCACACGCTCGGCGCGCTGGGCCCGACGCACGCCCTGTTCGCGAGCGCGCCCGCCTCGGC
CGGGCAGACCGCGCTCGACGAGCGCGCCGGCGCATCGGCGCCCGCGCCGCCGCGCGATGCGGCGCCCGCGTCGCGGGCGG
TGCGCGCATCGCTCGAGCGCATCGCGCGGATCGATCGCGACGGCCCGCGCCTGAACGCGATCATCGAATTGAATCCGGAT
GCCGAAGCGATCGCGCATGCGCTCGACGCCGAGCGGGCCGCGGGCGTCGCGCGCGGCCCGCTGCACGGCGTGACCGTCGC
GTTGAAGGACAACATCGCGACGGGCGACCGGATGTCGACGACGGCCGGCTCGCTCGCGCTCGACGGCGTGCGCGCGACGC
GCGATGCGCATCTCGTCGCGCGGCTGCGGCGCGCGGGGGCGGTGATCGTCGCGAAGGCCAACCTGAGCGAATGGGCGAAC
TTCCGCTCGACGCGCTCGACGAGCGGCTGGAGCGCGCGCGGCGGGCTGTCGCGCAACCCGTACGCGCTCGACCGGACGAC
GAGCGGATCGAGCTCCGGCTCGGCGGCGGCGGTGGCGGCGGGGCTCGTCGCCGTCTCGGTCGGCACCGAGACCGACGGCT
CGATCGTGTCGCCCGCCGCGATCAACGGCTGCGTCGGCCTGAAGCCGACGCTCGGGCGCGTGAGCCGAGACGGGATCGTG
CCGGTGTCGCACACGCAGGATACGGCGGGGCCGATCGCGCGCACGGTCCGCGACGCGGCGCGGCTGCTCGGCGCGCTCGC
GGGCGGCGACGCGCGCGACTCCGCAACGGCGAGCGCGCCCGCGCCGGCGGACTACGTCGCCGCGCTCGATGCGAATGCGC
TGCGCGGCGCGCGGCTCGGCATCGCGCGCGCGTACTTCACCGGGCACGACGAGGTGGACGTGCAGATCGAGCGCGCGATC
GCCGAGATGAAGCGGCTCGGCGCGGTCGTGATCGACCCGGTCGATCTGCCGAAAGCCGATTACGAGGAAGACGAGAAGGT
CGTGCTGCTGCACGAGTTCAAGCACGGCTTGCCGTCGTGGCTGCGGACGTTCGCGCCGCACGCGCGCGTGCGCACGCTCG
CCGACGTGATCGCGTTCAACGCGCGGCAGCATGCGCGGGAGATGCCGTATTTCGGGCAGGAGCTGCTGCTGCACGCGCAG
GAGGCGGGCGGGCTCGACGCCGCCGCGTACCGCGACGCGCTCGCCCGTTGCGGCCGCCGCGCGCGCGACGAGGGGCTCGC
GCGCGTGCTGCGCGAGCACCGGCTCGACGCGCTCGTCGCGCCGACCGAGGGCACCGCTTGGCTGATCGATCTGATCAACG
GCGACAGCGGCGGCGACGGCTTTTCGACGCCCGCCGCGGTCGCGGGTTTTCCGCATCTGACCGTGCCCGCCGGGCTCGTG
CGCGGCTTGCCGGTCGGGGTATCGTTCGTCGGCGCGCCGTGGAGCGAGGCGCGGCTGCTCGCGCTCGGCTACGCGTTCGA
GCAGGCCACGCAGTGGCGGCGCGAGCCGCGGTTCGTCGAGCGCTCGAACGTGCCGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
ACACTCCACCGACGCGCGCGCTCGCCGGACACGGCGGCGCGCCGCACGCGCGGCCGGCGTCCGGCCGCACGGCCGCATCA
CGACAACAGGACGTACCGGA

Downstream 100 bases:

>100_bases
ACCGGTTGACGCCGGGCCACCCCGCAGGCCGCGTCGAGGCGCGGCGGGCGCGCCCGCATGCGCCCGCCCCGGCGATCGCC
GTCGGCGCGCGGGATGCCGG

Product: amidase

Products: NA

Alternate protein names: Glu-ADT subunit A 1 [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MKRRQFLHTLGALGPTHALFASAPASAGQTALDERAGASAPAPPRDAAPASRAVRASLERIARIDRDGPRLNAIIELNPD
AEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMSTTAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWAN
FRSTRSTSGWSARGGLSRNPYALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLGIARAYFTGHDEVDVQIERAI
AEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSWLRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQ
EAGGLDAAAYRDALARCGRRARDEGLARVLREHRLDALVAPTEGTAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR

Sequences:

>Translated_528_residues
MKRRQFLHTLGALGPTHALFASAPASAGQTALDERAGASAPAPPRDAAPASRAVRASLERIARIDRDGPRLNAIIELNPD
AEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMSTTAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWAN
FRSTRSTSGWSARGGLSRNPYALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLGIARAYFTGHDEVDVQIERAI
AEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSWLRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQ
EAGGLDAAAYRDALARCGRRARDEGLARVLREHRLDALVAPTEGTAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR
>Mature_528_residues
MKRRQFLHTLGALGPTHALFASAPASAGQTALDERAGASAPAPPRDAAPASRAVRASLERIARIDRDGPRLNAIIELNPD
AEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMSTTAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWAN
FRSTRSTSGWSARGGLSRNPYALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLGIARAYFTGHDEVDVQIERAI
AEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSWLRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQ
EAGGLDAAAYRDALARCGRRARDEGLARVLREHRLDALVAPTEGTAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=491, Percent_Identity=29.938900203666, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI195972892, Length=228, Percent_Identity=30.2631578947368, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17543272, Length=426, Percent_Identity=27.4647887323944, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17537465, Length=305, Percent_Identity=26.2295081967213, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17556264, Length=224, Percent_Identity=30.3571428571429, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323950, Length=500, Percent_Identity=25, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319685, Length=236, Percent_Identity=33.4745762711864, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648113, Length=477, Percent_Identity=30.188679245283, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356731, Length=263, Percent_Identity=31.1787072243346, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644968, Length=482, Percent_Identity=27.3858921161826, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI161078093, Length=479, Percent_Identity=25.678496868476, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648435, Length=232, Percent_Identity=29.7413793103448, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648437, Length=232, Percent_Identity=29.7413793103448, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45550774, Length=232, Percent_Identity=29.7413793103448, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648441, Length=173, Percent_Identity=31.7919075144509, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648439, Length=173, Percent_Identity=31.7919075144509, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652985, Length=227, Percent_Identity=33.0396475770925, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922090, Length=227, Percent_Identity=33.0396475770925, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652981, Length=227, Percent_Identity=33.0396475770925, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652983, Length=227, Percent_Identity=33.0396475770925, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 55331; Mature: 55331

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRQFLHTLGALGPTHALFASAPASAGQTALDERAGASAPAPPRDAAPASRAVRASLER
CCHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
IARIDRDGPRLNAIIELNPDAEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMST
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCC
TAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWANFRSTRSTSGWSARGGLSRNP
CCCCCEECCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCC
YALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
EEEECCCCCCCCCCHHHHHHHHHEEEECCCCCCCEECCHHHCCCCCCCCCCCCCCCCCCE
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLG
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCHHHH
IARAYFTGHDEVDVQIERAIAEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSW
HHHHEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEHHHHCCHHHH
LRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQEAGGLDAAAYRDALARCGRR
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ARDEGLARVLREHRLDALVAPTEGTAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHH
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR
CCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
>Mature Secondary Structure
MKRRQFLHTLGALGPTHALFASAPASAGQTALDERAGASAPAPPRDAAPASRAVRASLER
CCHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
IARIDRDGPRLNAIIELNPDAEAIAHALDAERAAGVARGPLHGVTVALKDNIATGDRMST
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCC
TAGSLALDGVRATRDAHLVARLRRAGAVIVAKANLSEWANFRSTRSTSGWSARGGLSRNP
CCCCCEECCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCC
YALDRTTSGSSSGSAAAVAAGLVAVSVGTETDGSIVSPAAINGCVGLKPTLGRVSRDGIV
EEEECCCCCCCCCCHHHHHHHHHEEEECCCCCCCEECCHHHCCCCCCCCCCCCCCCCCCE
PVSHTQDTAGPIARTVRDAARLLGALAGGDARDSATASAPAPADYVAALDANALRGARLG
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCHHHH
IARAYFTGHDEVDVQIERAIAEMKRLGAVVIDPVDLPKADYEEDEKVVLLHEFKHGLPSW
HHHHEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEHHHHCCHHHH
LRTFAPHARVRTLADVIAFNARQHAREMPYFGQELLLHAQEAGGLDAAAYRDALARCGRR
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ARDEGLARVLREHRLDALVAPTEGTAWLIDLINGDSGGDGFSTPAAVAGFPHLTVPAGLV
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHH
RGLPVGVSFVGAPWSEARLLALGYAFEQATQWRREPRFVERSNVPAAR
CCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]