| Definition | Burkholderia pseudomallei K96243 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_006351 |
| Length | 3,173,005 |
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The map label for this gene is mrcA [H]
Identifier: 53723322
GI number: 53723322
Start: 3100875
End: 3103394
Strand: Reverse
Name: mrcA [H]
Synonym: BPSS2304
Alternate gene names: 53723322
Gene position: 3103394-3100875 (Counterclockwise)
Preceding gene: 53723323
Following gene: 53723309
Centisome position: 97.81
GC content: 71.87
Gene sequence:
>2520_bases GTGTCGTCCTTCCTCGAGCGTTGCGCGGCCTGGCTCGCCGCCGCGAAGCCGCACGCCGCCGCCGTCCTGCACCGCCTGCG CCACCCGACGCGGCGCGGCGTGCTGCTCGCCGTCGCCGCTCTCCCCGCGCTGTGCGTGCTCTACGTGCTCGCGCTGATCC CGTTCACGCCGAGCATCGGCGACATCCGCAAGGCGCGCGTCGACGCGCCCGCGCAGATCCTGTCCGCCGACGGCAAGCTG CTCGCCGAGTTCAAGCCGTCGAACCGCGAATGGGTGCCGCTCGCCGACATCTCGCCGAAGATGGTCGACGCGCTGATCTC GACCGAGGACCATCGCTTCTACGAGCACCACGGCCTCGACTGGCGGCGCACCGCGGGCGCCGCGCTGCGCACGTTCTCCG GCGACCGGCAGGGCGGCTCGACGATCACGCAGCAGCTCGCGCGCAACCTGTATCCGGACGAGATCGGCCGCGCGCCGACG CTCACGCGCAAGCTGAAGGAAGCGATCACCGCGCTGAAGATCGAGGCGGTCTACAGCAAGGCGCAGATCCTCGAGACGTA TCTGAACACGGTGCCGTTCCTGTACAACGCGTACGGCGTCGAGATGGCCGCGCGCACGTACTTCGACAAATCGGCCGACC AGCTCGACGCGCTCGACGCGGCGACGCTCGTCGGCATGCTCAAGGGCAACAGCTATTACAACCCGGTGCTGAACCCCGAG CGCGCGCTCGCGCGCCGCAACACGGTGCTCGCGCAGATGGTGAAGTACGGCAGGCTCTCGCCCGCCGCGTATGCGTCGCT GCAGAAGAAGCCGCTGCGCATCGATTTCGAGCGGCAGAAGGAGCCGCCCGGCCCCGCGCCGCATTTCGCGCAGCAACTGC GCAAGTGGCTGATCGCGTGGGCCGACCGCAACGATTACAACATCTACTCCGACGGCCTCGTCGTGCGCACGACGATCGAT TCGCGGCTGCAGACGTATGCGACGCAGGCGCTCGCGCGTCAGACCAACCAGCTGCAGGGCGTCGCGAACGGGATGTGGAA CGCCGGCAGCGGCTGCGCCCCCGGCAATCCGCTGTTTCGCGCATTCGTGCGCGAGACGCCGGAGTTCCGCGCGGCGCTCG ACGGCGGCGCGACCGGGGACGCCGCGCTCAAGCGCCTGCTCGCCGACCGCGGCTTCGCGCGCGCACTCTGCAAGGCGAAG GCCGACGTGCAGGCGGGCTTTCTCGCGATCGATCCGCGCAACGGGCAGATCAAGGCGTGGGTCGGCAGCCGCGATTTCAC GGCCGAGCCGTTCGATCACGTGCAGCAGGCGCGCCGGCAGCCGGGCTCGACGTTCAAGCCGTTCGTCTACGGCGCGGCGT TCGCGGCGGGCGCGACGCCCGACGATACGTTCGTCGATCAGCCGGTCGAGATCCCGCTCGCGGGCGGCGAGATCTGGCGG CCCGACGACGACGCGCCGCCCACGAACAAGCCGATGACGCTGCGCGACGCGATCGCGTACTCGCGCAACCGGATCACCGC GCAACTGATGATGAAGGTCGGCCCGCAGAAGGTGGCGCGCCTCGCGCGCGCGATGGGCGTGCGCGACAGCGCGCTCGATG CGGTGCCGTCGCTCGCGCTCGGCACGAGCCCCGTGACGCTCAAGGAGATGGTGTCCGCCTACGCGACGATCGCGAACGTC GGCGAATACGTCGAGCCGCGGATGGTCACGCGCATCGAGGGCCGCAACGGCGAGGTGCTCGCCGAGTTCGCGAGCGCGAC GCCCGAGCGCGCGCTCGACGCGGCGGCGGCGCGCACGCTGATCGACGTGATGCGCGGCGTCGTCGAGCGCGGCACCGGCG CGGCGATCCGCTCGCGCTACGGGATTCGCGCGGACGTCGCCGGCAAGACCGGCACGACGCAGGGCGACACCGACGGCTGG TTCATCCTGATGCAGCCCGAGCTTGTCGCGGGCGCGTGGGTCGGCTTCGACGACGGCCGCGTGACGCTCGGCGGCGATTG GGGGCAAGGCGCGCGCAGCGCGCTGCCGATCGTCGGCGATTTCTATCAGCGGGCGATTCGCGCGCGGCTCGTCGATACGC GCGAACGCTTCGCGACCGAAGCGCCGCCGAGCGCGTTCGACACGTTCCGCAACAAGCTCGGCGACTGGTATCGCTACCTG TTCGAGAAGCCCGAGCCGCCGCGCAAGGCCGCGCCGCCGAAAGCGCCGCGCGCGCCGCTCGAGGAGGTGATGCCGGCTTC CGAGGTCGAGGCGGCGTCGGCGGCGGTCGCGCGCGCCGCGTCGGAAGCGGCTGCAGTGGCATCGGCCGCGTCGACCGCAT CGGCCGCACCGCCGGCGAGCGGCGTGCCGTTCGCGCCGGGCGGCGCGTCGGCGCCGGCGCTGCCGCCGCTGTTGCCGCCG ATGCCACAGTCTGCTCCGTTGCCGCCTGCCGCGCAGCCGGGCAGCAGCCTGCCGAACGACAACGCGCCGATGTCGCCGAC GCCGACGCCCGATGCGCCGGCCGCGGGCGGCAGCAATTAG
Upstream 100 bases:
>100_bases CACGCGCCGAATCCGCCCTCCCGCCGCGCCCTGGCCGCCGCGTTTGGTACGATTCACGCTTTCCCATCCCTATTCGCCTC ACCGCGTGAACCGCCGAATC
Downstream 100 bases:
>100_bases CGAAGACCGGCGGCGACGGTTCGTTCGCGGCGCGCGTTGCGTTGCCCCGTCGCTTTGGCCGCCGCCGCCGCCCGCCTCGG CCCGCCTCGGCCCGCGTCGA
Product: penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 839; Mature: 838
Protein sequence:
>839_residues MSSFLERCAAWLAAAKPHAAAVLHRLRHPTRRGVLLAVAALPALCVLYVLALIPFTPSIGDIRKARVDAPAQILSADGKL LAEFKPSNREWVPLADISPKMVDALISTEDHRFYEHHGLDWRRTAGAALRTFSGDRQGGSTITQQLARNLYPDEIGRAPT LTRKLKEAITALKIEAVYSKAQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDALDAATLVGMLKGNSYYNPVLNPE RALARRNTVLAQMVKYGRLSPAAYASLQKKPLRIDFERQKEPPGPAPHFAQQLRKWLIAWADRNDYNIYSDGLVVRTTID SRLQTYATQALARQTNQLQGVANGMWNAGSGCAPGNPLFRAFVRETPEFRAALDGGATGDAALKRLLADRGFARALCKAK ADVQAGFLAIDPRNGQIKAWVGSRDFTAEPFDHVQQARRQPGSTFKPFVYGAAFAAGATPDDTFVDQPVEIPLAGGEIWR PDDDAPPTNKPMTLRDAIAYSRNRITAQLMMKVGPQKVARLARAMGVRDSALDAVPSLALGTSPVTLKEMVSAYATIANV GEYVEPRMVTRIEGRNGEVLAEFASATPERALDAAAARTLIDVMRGVVERGTGAAIRSRYGIRADVAGKTGTTQGDTDGW FILMQPELVAGAWVGFDDGRVTLGGDWGQGARSALPIVGDFYQRAIRARLVDTRERFATEAPPSAFDTFRNKLGDWYRYL FEKPEPPRKAAPPKAPRAPLEEVMPASEVEAASAAVARAASEAAAVASAASTASAAPPASGVPFAPGGASAPALPPLLPP MPQSAPLPPAAQPGSSLPNDNAPMSPTPTPDAPAAGGSN
Sequences:
>Translated_839_residues MSSFLERCAAWLAAAKPHAAAVLHRLRHPTRRGVLLAVAALPALCVLYVLALIPFTPSIGDIRKARVDAPAQILSADGKL LAEFKPSNREWVPLADISPKMVDALISTEDHRFYEHHGLDWRRTAGAALRTFSGDRQGGSTITQQLARNLYPDEIGRAPT LTRKLKEAITALKIEAVYSKAQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDALDAATLVGMLKGNSYYNPVLNPE RALARRNTVLAQMVKYGRLSPAAYASLQKKPLRIDFERQKEPPGPAPHFAQQLRKWLIAWADRNDYNIYSDGLVVRTTID SRLQTYATQALARQTNQLQGVANGMWNAGSGCAPGNPLFRAFVRETPEFRAALDGGATGDAALKRLLADRGFARALCKAK ADVQAGFLAIDPRNGQIKAWVGSRDFTAEPFDHVQQARRQPGSTFKPFVYGAAFAAGATPDDTFVDQPVEIPLAGGEIWR PDDDAPPTNKPMTLRDAIAYSRNRITAQLMMKVGPQKVARLARAMGVRDSALDAVPSLALGTSPVTLKEMVSAYATIANV GEYVEPRMVTRIEGRNGEVLAEFASATPERALDAAAARTLIDVMRGVVERGTGAAIRSRYGIRADVAGKTGTTQGDTDGW FILMQPELVAGAWVGFDDGRVTLGGDWGQGARSALPIVGDFYQRAIRARLVDTRERFATEAPPSAFDTFRNKLGDWYRYL FEKPEPPRKAAPPKAPRAPLEEVMPASEVEAASAAVARAASEAAAVASAASTASAAPPASGVPFAPGGASAPALPPLLPP MPQSAPLPPAAQPGSSLPNDNAPMSPTPTPDAPAAGGSN >Mature_838_residues SSFLERCAAWLAAAKPHAAAVLHRLRHPTRRGVLLAVAALPALCVLYVLALIPFTPSIGDIRKARVDAPAQILSADGKLL AEFKPSNREWVPLADISPKMVDALISTEDHRFYEHHGLDWRRTAGAALRTFSGDRQGGSTITQQLARNLYPDEIGRAPTL TRKLKEAITALKIEAVYSKAQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDALDAATLVGMLKGNSYYNPVLNPER ALARRNTVLAQMVKYGRLSPAAYASLQKKPLRIDFERQKEPPGPAPHFAQQLRKWLIAWADRNDYNIYSDGLVVRTTIDS RLQTYATQALARQTNQLQGVANGMWNAGSGCAPGNPLFRAFVRETPEFRAALDGGATGDAALKRLLADRGFARALCKAKA DVQAGFLAIDPRNGQIKAWVGSRDFTAEPFDHVQQARRQPGSTFKPFVYGAAFAAGATPDDTFVDQPVEIPLAGGEIWRP DDDAPPTNKPMTLRDAIAYSRNRITAQLMMKVGPQKVARLARAMGVRDSALDAVPSLALGTSPVTLKEMVSAYATIANVG EYVEPRMVTRIEGRNGEVLAEFASATPERALDAAAARTLIDVMRGVVERGTGAAIRSRYGIRADVAGKTGTTQGDTDGWF ILMQPELVAGAWVGFDDGRVTLGGDWGQGARSALPIVGDFYQRAIRARLVDTRERFATEAPPSAFDTFRNKLGDWYRYLF EKPEPPRKAAPPKAPRAPLEEVMPASEVEAASAAVARAASEAAAVASAASTASAAPPASGVPFAPGGASAPALPPLLPPM PQSAPLPPAAQPGSSLPNDNAPMSPTPTPDAPAAGGSN
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=588, Percent_Identity=31.1224489795918, Blast_Score=262, Evalue=7e-71, Organism=Escherichia coli, GI1786343, Length=589, Percent_Identity=30.0509337860781, Blast_Score=185, Evalue=1e-47, Organism=Escherichia coli, GI1788867, Length=270, Percent_Identity=31.4814814814815, Blast_Score=103, Evalue=6e-23, Organism=Escherichia coli, GI1789601, Length=174, Percent_Identity=37.3563218390805, Blast_Score=85, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 90084; Mature: 89953
Theoretical pI: Translated: 9.67; Mature: 9.67
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSFLERCAAWLAAAKPHAAAVLHRLRHPTRRGVLLAVAALPALCVLYVLALIPFTPSIG CHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH DIRKARVDAPAQILSADGKLLAEFKPSNREWVPLADISPKMVDALISTEDHRFYEHHGLD HHHHHHCCCCHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHCCCC WRRTAGAALRTFSGDRQGGSTITQQLARNLYPDEIGRAPTLTRKLKEAITALKIEAVYSK HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH AQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDALDAATLVGMLKGNSYYNPVLNPE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHH RALARRNTVLAQMVKYGRLSPAAYASLQKKPLRIDFERQKEPPGPAPHFAQQLRKWLIAW HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEECHHHCCCCCCCCHHHHHHHHHHHHHH ADRNDYNIYSDGLVVRTTIDSRLQTYATQALARQTNQLQGVANGMWNAGSGCAPGNPLFR CCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH AFVRETPEFRAALDGGATGDAALKRLLADRGFARALCKAKADVQAGFLAIDPRNGQIKAW HHHHCCCHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCCCEEEEE VGSRDFTAEPFDHVQQARRQPGSTFKPFVYGAAFAAGATPDDTFVDQPVEIPLAGGEIWR ECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCC PDDDAPPTNKPMTLRDAIAYSRNRITAQLMMKVGPQKVARLARAMGVRDSALDAVPSLAL CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHC GTSPVTLKEMVSAYATIANVGEYVEPRMVTRIEGRNGEVLAEFASATPERALDAAAARTL CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH IDVMRGVVERGTGAAIRSRYGIRADVAGKTGTTQGDTDGWFILMQPELVAGAWVGFDDGR HHHHHHHHHCCCCHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHEEEECCCCE VTLGGDWGQGARSALPIVGDFYQRAIRARLVDTRERFATEAPPSAFDTFRNKLGDWYRYL EEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH FEKPEPPRKAAPPKAPRAPLEEVMPASEVEAASAAVARAASEAAAVASAASTASAAPPAS HCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC GVPFAPGGASAPALPPLLPPMPQSAPLPPAAQPGSSLPNDNAPMSPTPTPDAPAAGGSN CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure SSFLERCAAWLAAAKPHAAAVLHRLRHPTRRGVLLAVAALPALCVLYVLALIPFTPSIG HHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH DIRKARVDAPAQILSADGKLLAEFKPSNREWVPLADISPKMVDALISTEDHRFYEHHGLD HHHHHHCCCCHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHCCCC WRRTAGAALRTFSGDRQGGSTITQQLARNLYPDEIGRAPTLTRKLKEAITALKIEAVYSK HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH AQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDALDAATLVGMLKGNSYYNPVLNPE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHH RALARRNTVLAQMVKYGRLSPAAYASLQKKPLRIDFERQKEPPGPAPHFAQQLRKWLIAW HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEECHHHCCCCCCCCHHHHHHHHHHHHHH ADRNDYNIYSDGLVVRTTIDSRLQTYATQALARQTNQLQGVANGMWNAGSGCAPGNPLFR CCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH AFVRETPEFRAALDGGATGDAALKRLLADRGFARALCKAKADVQAGFLAIDPRNGQIKAW HHHHCCCHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCCCEEEEE VGSRDFTAEPFDHVQQARRQPGSTFKPFVYGAAFAAGATPDDTFVDQPVEIPLAGGEIWR ECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCC PDDDAPPTNKPMTLRDAIAYSRNRITAQLMMKVGPQKVARLARAMGVRDSALDAVPSLAL CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHC GTSPVTLKEMVSAYATIANVGEYVEPRMVTRIEGRNGEVLAEFASATPERALDAAAARTL CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH IDVMRGVVERGTGAAIRSRYGIRADVAGKTGTTQGDTDGWFILMQPELVAGAWVGFDDGR HHHHHHHHHCCCCHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHEEEECCCCE VTLGGDWGQGARSALPIVGDFYQRAIRARLVDTRERFATEAPPSAFDTFRNKLGDWYRYL EEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH FEKPEPPRKAAPPKAPRAPLEEVMPASEVEAASAAVARAASEAAAVASAASTASAAPPAS HCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC GVPFAPGGASAPALPPLLPPMPQSAPLPPAAQPGSSLPNDNAPMSPTPTPDAPAAGGSN CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA