Click here to switch to the map view.

The map label for this gene is atpB2 [H]

Identifier: 53722970

GI number: 53722970

Start: 2636155

End: 2636856

Strand: Reverse

Name: atpB2 [H]

Synonym: BPSS1949

Alternate gene names: 53722970

Gene position: 2636856-2636155 (Counterclockwise)

Preceding gene: 53722971

Following gene: 53722969

Centisome position: 83.1

GC content: 68.95

Gene sequence:

>702_bases
ATGAACGCGTCGCCGCTGTCGACCGTGCCGCTGTTCTCGGTCGGCCCCGTCGGCATCTCGGCGCCCGTGCTCGCGACGTG
GGCGATCATGGCCGTGCTCGTCGCGCTCGCGCTCGTCGCGCGCCGGCGGCTGAGCGTCGATGCGCCGTCGCGGCTGCAAA
GCGTGCTCGAGCTGTTCGTCGCGACCGTCGACGCGCAGATCGCCGACACGATGCAGACGCCGCCCGCGCGCTATCGCGCG
CTGATCGGCACGATCTTCGTGCTCGTGTTCTGCGCGAACGGCGCGTCGCTCGTGCCGGGCGTCGAGCCGCCGACCGCGCA
TCTCGAGACCGACGCCGCGCTCGCGCTCGTCGTGCTCGCGGCGACGCTCTATTACGGCGTGCGCGCGCGCGGCGTGCGCG
GCTATCTGGCGACGTTCGCCGAGCCGACCTGGGTGATGATTCCGTTGAACGTCGTCGAGCAGCTCACGCGCACGTTCTCG
CTGATCGTGCGCCTGTTCGGCAACGTGATGAGCGGCGTGTTCGTGATCGGCATCGTGCTGTCGCTCGCCGGCTTGTTCGT
GCCGATTCCGCTGATGGCGCTCGATCTGCTGACGGGCACGGTGCAGGCGTACATTTTCATGGTGCTGTCGATGGTGTTCA
TCGGCGCGGCCGTATCCGGTGACGAAACTTCCGCGCCGCGGCGCGGGCAGGAGAACACATGA

Upstream 100 bases:

>100_bases
CGCGGGCGGGCTTCGGCATGCTCGTTGCGGGCTCCGCGGGGTTTTTCGCCGCGCGGGCGATCGCGGTCCGCCGCGCGGCC
GCGTTGACGGGAGCGCGGCG

Downstream 100 bases:

>100_bases
ACAATCTCATCGAAGTGGTCAGCATCGCGGCGGCCGCGCTCGCCGTGTCGTTCGGCGCGATCGGCCCCGCGCTCGCGGAA
GGGCGCGCGGTCGGCGCGGC

Product: F0F1 ATP synthase subunit A

Products: ATP; H+; H2O [C]

Alternate protein names: ATP synthase F0 sector subunit a 2; F-ATPase subunit 6 2 [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRA
LIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFS
LIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT

Sequences:

>Translated_233_residues
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRA
LIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFS
LIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>Mature_233_residues
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRA
LIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFS
LIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=203, Percent_Identity=26.1083743842365, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14 [C]

Molecular weight: Translated: 24629; Mature: 24629

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVL
HHHHHHHHHCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVL
HHHHHHHHHCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP; H+; Phosphate [C]

Specific reaction: ADP + (4) H+ + Phosphate <==> ATP + (3) H+ + H2O [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA