Click here to switch to the map view.

The map label for this gene is mhpF

Identifier: 53722827

GI number: 53722827

Start: 2467265

End: 2468158

Strand: Reverse

Name: mhpF

Synonym: BPSS1808

Alternate gene names: 53722827

Gene position: 2468158-2467265 (Counterclockwise)

Preceding gene: 53722828

Following gene: 53722826

Centisome position: 77.79

GC content: 63.42

Gene sequence:

>894_bases
ATGAAGAGCAAGTCATCGCGCACGCGGGTGGCGATCCTGGGCTCGGGCAGCATCGGGCTCGATCTGATGTTCAAAGTCAA
GGCATCCGAGCAATTCGATCTGAAGTTCGTCGTCGGACGCAATGCGAACAGCGACGGGCTGCGGCTCGCGCGCAGTTGCA
ACGTGGAGACATCGAGCGACGGTCTCGATTTTCTGAAGGCGCACGAGGATGCGTACGACCTCGTGTTCGACGCGACATCG
GCCGCCGCGCACAAGGTCAACAACCGCTTCTTCTCCGACGCGGGCAAGTTCGTGATTGATCTGACGCCCGCGAAGGTCGG
CCGCCTGTGCGTGCCGTGCATCAATCTGGACGACATGGGCGCCGAGCAGAACGTGAACCTGATCACCTGCGGCGGGCAGG
CGAGCCTGCCGCTCGCGTACGCGCTGAAGCAGGCGGTCGACGAGATCGATTACCTGGAGGTGGTGTCGGCGATCGCGTCG
CGCAGCGCCGGCATCGCGACGCGCGAGAACATCGACGAATACATGACGACGACCGAGTACGCGCTCGCGAAATTCAGCGA
TGCGAAGAAGACGAAGGCGATCCTCAACATCAATCCGGCCGAGCCCGGTGTGCGGATGCAGACGACGCTCTATGCGTACG
CGCGCTATCGCGATTTCGACCGCGTGCGCGCAAGCGTTGCCGACATGGTCGAGAAGGTGCGCGAATACGTGCCCGGCTAT
CGGCTCGTCGTCGAGCCGCTCGAAAGCCAGGGGAGGATCACGATCGGTCTCACCGTGCGCGGGCGCGGCGACTATCTGCC
CGAGTACGCGGGCAATCTGGACATCATCAACTGCGCGGCGCTCGCGGTCGCCTCGCATCGGCACGCAACCGCCAGACTAG
GAGCCACACAATGA

Upstream 100 bases:

>100_bases
GCGAGCTCGAGCGCGTGCTCGCGCGCGCCGCGCAGGACGAGCCGAACGGCATGCGCGAGCCGGCGGCGCGCATGAGTCAT
TTGACGGAGGAGAGCGGAAC

Downstream 100 bases:

>100_bases
TACTGATCAGCGATGCGACCTTGCGCGACGGCAACCATGCGATTCGTCACCAACTGAGCGCCGCGCAGATACATGCGTAT
GCGCGCGCGGCCGACGAAGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATS
AAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIAS
RSAGIATRENIDEYMTTTEYALAKFSDAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ

Sequences:

>Translated_297_residues
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATS
AAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIAS
RSAGIATRENIDEYMTTTEYALAKFSDAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
>Mature_297_residues
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATS
AAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIAS
RSAGIATRENIDEYMTTTEYALAKFSDAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=301, Percent_Identity=41.5282392026578, Blast_Score=214, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 32346; Mature: 32346

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSD
CCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEHHHCCCCCCCC
GLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMG
CHHHHHHCCCHHHHEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHCCEEEEECCCCCCC
AEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSAGIATRENIDEYMTTTEY
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALAKFSDAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
HHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
EEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCEEHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSD
CCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEHHHCCCCCCCC
GLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMG
CHHHHHHCCCHHHHEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHCCEEEEECCCCCCC
AEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSAGIATRENIDEYMTTTEY
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALAKFSDAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
HHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
EEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCEEHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA