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The map label for this gene is fhaC [H]

Identifier: 53722749

GI number: 53722749

Start: 2370877

End: 2372568

Strand: Reverse

Name: fhaC [H]

Synonym: BPSS1728

Alternate gene names: 53722749

Gene position: 2372568-2370877 (Counterclockwise)

Preceding gene: 53722750

Following gene: 53722748

Centisome position: 74.77

GC content: 63.77

Gene sequence:

>1692_bases
TTGACGCATATCGTTTTGACGCTTGCCATGACGGTGTTGCTGGCGGGCCGCTCGGCGCCGGCAAGCGCGTTCGGGCCGAC
GGTGCAGGACCGGGAGCGGGATCTGGGGGAGAAGGCGCGACGGCAGCAGATGATCGAACAGCATAGGCGGGGGCATGCGG
CCGAGCCGGCGGCCGGGTTGCCGGCGCCAGTGCAAGCACCCGAGTTGGGCGGTGCGCGTTTCCCGATCACGCAAATCGAA
GTGCGGGGCGGGGCGCGCCATAGCCGGGAGATCGACCGGATTGTCGAGCGCTACCGGGGCGCGACCATGGGGCAGGCGGA
GATTTTCGCGCTGTTGCGTGATCTGATGAATTTCTACTATGGCCGCGGTTATATCACGACCGGCGTGTCGCTCGCCGAGC
AAAACCTGTCGAGCGGGAAGCTGATCGTGGTGGTCCATTGGGGCTACGTGAAGGGATGGCGCGTGAACGGCAAGGCGCCG
GAGGGCATGCGCGAGCGGTTGATGTTGAGCAGCGCGATGCCTGGCATAGAAGGTTCCGTTTTGAACATCCACGATATCGA
CCAGGCGATCGAGAATCTGAACGGCTTGGGCAGAGCCGCCAAGATCAACGTCGTCCCCGCCGAGGAAGCCGGGTATTCCT
ATCTGGACGTCGTTTTGCAACGCTCGAAGCCGTTCGCGGTGTCGGCGTCGGTCGATAACTCGGGTCTCGGCGATCGAGCG
GGCGACGGCTTATACCGGTATGGCGTCGATATCGCGGTGGCGCACCTGCTGGGCTGGAACGACGTGCTGACGCTCTCGGC
CGGCCGTCGCTACTACCAGGACCCCGCCCATCATGCCTACGATTCGCTGGCCGTGTCATACGGATGGCGCGTGGGCCGCT
GGAGCGCCGATCTGCGGTATATCGCGCAGCCGACCAAAAGCCTCCTTTCCGGAACCTATGGTGACTACCAACTGAGCGGC
AATACGCAGGATGTCAACCTGCGCGTGTCGCGCGTGCTTCGGCGCTGGCGGACCGGCACGGATGCCGTCTACGTTGCGAT
CGACCGCAAGCGCGTGCGCAACTATATCGACGACACGCTGATCGAGATCAACAGCAACACCCATACGAGCGTCACGGCGG
GAGTCAATCGGCTGGACAGTCTGTTCGGCGGAGTCGTATTCGCGGATGGGGGCTGGACGAGGGGCGTGGGCTGGCTGGGG
GCGAGCGAGGACCCAGTGTCCGCCGGGCAAGGGCCGCTGTCGCGTTACGACAAATTCAATCTGAACCTGAACTGGTCGCG
CGACTTCACGGCGGGCTCGTTGCGAGCCCGTTACACGGCGGCGATGGGGGCGCAGTATTCGAAGGATGACCTGTACTACG
ACAGCAAGTTCGTCATTGGCGACCAGTACACGGTGCGCGGCTTCAAGATCCGGTCTGCCTATGGGGATAGCGGCGTGTCT
GTATCGAACACGCTGAGCTTTCCGTTTCCGACGTCGATCGGAACGGTCACACCGTTGGTCGGTGTGGATTGGGGTGCCGT
CGGGAACAACGGCGAAGCGGACAATGGCGGCTGGATCGGCGCAGTTGCGGGCGGGCTCCGGGTGTCGACGAAATGGGCCA
ATGCGGCGGTGACCATCGGCAAGCCGTTCAGGGCGCTGCCGGGCATGGGGTACGGGGTGGTCTGGTATTTGAGCGCATCA
GCCACGTATTAG

Upstream 100 bases:

>100_bases
ATCGGCGGCCCGCCAATCGGATGACGGCGTTGGCAAGGGCATTCGATCGGCGCGAGCGGCCAGTCGGGAAGAGCGGGCGC
ACGGGGCGTACGGGCGCGTG

Downstream 100 bases:

>100_bases
CCACGGGCCGTGCGCATACGAACCGGCGGTCGTTTCGCCGAGCGTTGAATCGATACATGGCATGGAATGCCAATGATCAG
TCATGCAGAGGAATGAGGTC

Product: secretion/activator protein

Products: NA

Alternate protein names: TpsB transporter [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MTHIVLTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQAPELGGARFPITQIE
VRGGARHSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAP
EGMRERLMLSSAMPGIEGSVLNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRA
GDGLYRYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPTKSLLSGTYGDYQLSG
NTQDVNLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLG
ASEDPVSAGQGPLSRYDKFNLNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVS
VSNTLSFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRALPGMGYGVVWYLSAS
ATY

Sequences:

>Translated_563_residues
MTHIVLTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQAPELGGARFPITQIE
VRGGARHSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAP
EGMRERLMLSSAMPGIEGSVLNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRA
GDGLYRYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPTKSLLSGTYGDYQLSG
NTQDVNLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLG
ASEDPVSAGQGPLSRYDKFNLNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVS
VSNTLSFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRALPGMGYGVVWYLSAS
ATY
>Mature_562_residues
THIVLTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGLPAPVQAPELGGARFPITQIEV
RGGARHSREIDRIVERYRGATMGQAEIFALLRDLMNFYYGRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPE
GMRERLMLSSAMPGIEGSVLNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRAG
DGLYRYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRYIAQPTKSLLSGTYGDYQLSGN
TQDVNLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTLIEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGA
SEDPVSAGQGPLSRYDKFNLNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVSV
SNTLSFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIGKPFRALPGMGYGVVWYLSASA
TY

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of filamentous hemagglutinin (FHA) [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 61180; Mature: 61048

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIVLTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGL
CCEEHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PAPVQAPELGGARFPITQIEVRGGARHSREIDRIVERYRGATMGQAEIFALLRDLMNFYY
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPEGMRERLMLSSAMPGIEGSV
CCCEEECCHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCE
LNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRA
EEHHHHHHHHHHHHCCCCEEEEEEEECHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCC
GDGLYRYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRY
CCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCHHHHHHHHHHHCCCEEECCCCCHHH
IAQPTKSLLSGTYGDYQLSGNTQDVNLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTL
HHHHHHHHHCCCCCCEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCEE
IEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGASEDPVSAGQGPLSRYDKFN
EEECCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEECCCCCCCCCCCCCCCHHHCCEEE
LNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVS
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEEECCCEEEEEEEEEECCCCCCCE
VSNTLSFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIG
ECCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEEC
KPFRALPGMGYGVVWYLSASATY
CCHHHCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
THIVLTLAMTVLLAGRSAPASAFGPTVQDRERDLGEKARRQQMIEQHRRGHAAEPAAGL
CEEHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PAPVQAPELGGARFPITQIEVRGGARHSREIDRIVERYRGATMGQAEIFALLRDLMNFYY
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GRGYITTGVSLAEQNLSSGKLIVVVHWGYVKGWRVNGKAPEGMRERLMLSSAMPGIEGSV
CCCEEECCHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCE
LNIHDIDQAIENLNGLGRAAKINVVPAEEAGYSYLDVVLQRSKPFAVSASVDNSGLGDRA
EEHHHHHHHHHHHHCCCCEEEEEEEECHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCC
GDGLYRYGVDIAVAHLLGWNDVLTLSAGRRYYQDPAHHAYDSLAVSYGWRVGRWSADLRY
CCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCHHHHHHHHHHHCCCEEECCCCCHHH
IAQPTKSLLSGTYGDYQLSGNTQDVNLRVSRVLRRWRTGTDAVYVAIDRKRVRNYIDDTL
HHHHHHHHHCCCCCCEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCEE
IEINSNTHTSVTAGVNRLDSLFGGVVFADGGWTRGVGWLGASEDPVSAGQGPLSRYDKFN
EEECCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEECCCCCCCCCCCCCCCHHHCCEEE
LNLNWSRDFTAGSLRARYTAAMGAQYSKDDLYYDSKFVIGDQYTVRGFKIRSAYGDSGVS
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEEECCCEEEEEEEEEECCCCCCCE
VSNTLSFPFPTSIGTVTPLVGVDWGAVGNNGEADNGGWIGAVAGGLRVSTKWANAAVTIG
ECCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEEC
KPFRALPGMGYGVVWYLSASATY
CCHHHCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]