Click here to switch to the map view.

The map label for this gene is lysN [H]

Identifier: 53722488

GI number: 53722488

Start: 2001096

End: 2002322

Strand: Reverse

Name: lysN [H]

Synonym: BPSS1467

Alternate gene names: 53722488

Gene position: 2002322-2001096 (Counterclockwise)

Preceding gene: 53722489

Following gene: 53722487

Centisome position: 63.1

GC content: 74.16

Gene sequence:

>1227_bases
ATGACGCTCGCCGCCGCCGTCGATTATCCGTTCGCCGCGCCGTTCGCCGATCCGCAGGGCTCGCCGATCCGCGAGCTGTT
CAAGCACGTCGGCAAGCCGGGGATGATCTCGTTCGCGGGCGGCTATCCGTCCGCCGAGCTGTTCGACCGCGAGGGCATCG
CGGCGGCGTTCGCCGACGCGGCCCGCGACGATCCGGTGGCCTGCCTGCAATATGGCGACACCGCCGGCCAGCCCGGCCTG
CGCGCCGCGCTCGCCGACTGGATGACGCGCGCGCGCGGCGTCGCGTGCGACGCTTCGCAGGTGCTCGTCACGACGGGCTC
GCAGCAAGGCTTCGATCTGCTCGTGCGCGCGCTGATCGAGCCGGGCGACGTCGCGCTCGTCGAGGCGCCCGCGTATCCGG
CCGCGCTGCAGGCGCTGCGGCTCGCGGGCGCGAAGCTCGTGCCGGTGCGCACCGATGCCGACGGCGTCGACCCCGACGCG
CTCGCCGCGCAGCTTGCCGCGTGGCCCGCGGCCGAGCGCCGTCCGAAGCTGCTGTATACGGTGCCGACGTTCGCGAATCC
GACCGGCGCGACGCTGCCGCCGGCGCGCCGCGCGCGGCTCGCGGCGGTCGCGGCCGACGCGCGGCTCGTGCTCGTCGAGG
ACGATCCGTACGCGGACCTGCGTTTCGCCGGCGAGCCCGTGAAGCCCGTGCTCGCGCATGACGGCGCGTCGGACTGGACC
GTCTATCTCGGCAGCCTGTCGAAAATCGTCGCGCCGGGCCTGCGGATCGGCTGGGCGGTCGCGCCCGCCGCGGTTCTGCG
CCGGATGACCGTGGCGAAGCAGACGAGCGATTTGTGCACCGCGCCGATCGCGCAGGAAGCGATCCGCCGCTACCTGGCGA
GCGGCCGGCTTGCCGCGCATTTGCGCACGATCGCGCAGACTTACGGCAGCCGTTGCCGCGCGCTCGTGAGCGCGCTCGCG
CAATTCGTGCCGGACGATGTCGAATGGCGCGAGCCGTCGGGCGGCATGTTCGTGTGGGCGCGCCTCGGCGGCGGCCGCGA
CGCGTCCGAGGTGCTCAAGCGCGCGCTCGAGCACAACGTGATGTACGTGCCGGGCGCGGCGTTCTACGCGCGCGACGCGG
ATGCGGGCAGCCTGCGGCTGTCGTTCGCCGCGCCGGGCGAAGCGGAGATTTTCGAGGGCGTGCGCCGGCTGCGCGCGGCG
CTCGCGGCGTGCCGCCAGCGCACGTGA

Upstream 100 bases:

>100_bases
CGCGGGCAATGCGACCGGCATCTTCAAGATGACGGCCGCGGCCTGATTCGCAGCGTCCCCGATTCGCCTGTTGCCCGACT
TCCATCGCACCGGAGCCGCC

Downstream 100 bases:

>100_bases
CGCACGTGACGCACGTGCGGCGGGAGCGCCGCGCGCCGGGCACGCGAGCCCGCCGATAGGCCGAATGGCCGGTGCGCTTG
CATGCGGCGCGCGAACGCGG

Product: aminotransferase protein

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADAARDDPVACLQYGDTAGQPGL
RAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIEPGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDA
LAAQLAAWPAAERRPKLLYTVPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAHLRTIAQTYGSRCRALVSALA
QFVPDDVEWREPSGGMFVWARLGGGRDASEVLKRALEHNVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAA
LAACRQRT

Sequences:

>Translated_408_residues
MTLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADAARDDPVACLQYGDTAGQPGL
RAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIEPGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDA
LAAQLAAWPAAERRPKLLYTVPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAHLRTIAQTYGSRCRALVSALA
QFVPDDVEWREPSGGMFVWARLGGGRDASEVLKRALEHNVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAA
LAACRQRT
>Mature_407_residues
TLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADAARDDPVACLQYGDTAGQPGLR
AALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIEPGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDAL
AAQLAAWPAAERRPKLLYTVPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWTV
YLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAHLRTIAQTYGSRCRALVSALAQ
FVPDDVEWREPSGGMFVWARLGGGRDASEVLKRALEHNVMYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAAL
AACRQRT

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=393, Percent_Identity=31.0432569974555, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI33469970, Length=393, Percent_Identity=31.0432569974555, Blast_Score=176, Evalue=5e-44,
Organism=Escherichia coli, GI1787710, Length=350, Percent_Identity=30, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790797, Length=394, Percent_Identity=25.8883248730964, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1788722, Length=348, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=24.4623655913978, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=497, Percent_Identity=24.3460764587525, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6321929, Length=396, Percent_Identity=23.4848484848485, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6321000, Length=397, Percent_Identity=24.9370277078086, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356535, Length=413, Percent_Identity=25.4237288135593, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43169; Mature: 43037

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADA
CCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCHHHHHHHH
ARDDPVACLQYGDTAGQPGLRAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIE
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCC
PGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDALAAQLAAWPAAERRPKLLYT
CCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEE
VPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
CCCCCCCCCCCCCCHHHHHHHEEECCCEEEEECCCCCCCEEECCCCCCHHHHCCCCCCHH
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
LRTIAQTYGSRCRALVSALAQFVPDDVEWREPSGGMFVWARLGGGRDASEVLKRALEHNV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCE
MYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAALAACRQRT
EEECCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLAAAVDYPFAAPFADPQGSPIRELFKHVGKPGMISFAGGYPSAELFDREGIAAAFADA
CEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHCCCCHHHHHHHH
ARDDPVACLQYGDTAGQPGLRAALADWMTRARGVACDASQVLVTTGSQQGFDLLVRALIE
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCC
PGDVALVEAPAYPAALQALRLAGAKLVPVRTDADGVDPDALAAQLAAWPAAERRPKLLYT
CCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEE
VPTFANPTGATLPPARRARLAAVAADARLVLVEDDPYADLRFAGEPVKPVLAHDGASDWT
CCCCCCCCCCCCCCHHHHHHHEEECCCEEEEECCCCCCCEEECCCCCCHHHHCCCCCCHH
VYLGSLSKIVAPGLRIGWAVAPAAVLRRMTVAKQTSDLCTAPIAQEAIRRYLASGRLAAH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
LRTIAQTYGSRCRALVSALAQFVPDDVEWREPSGGMFVWARLGGGRDASEVLKRALEHNV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCE
MYVPGAAFYARDADAGSLRLSFAAPGEAEIFEGVRRLRAALAACRQRT
EEECCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA