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The map label for this gene is aphA [H]

Identifier: 53722385

GI number: 53722385

Start: 1860467

End: 1862680

Strand: Reverse

Name: aphA [H]

Synonym: BPSS1360

Alternate gene names: 53722385

Gene position: 1862680-1860467 (Counterclockwise)

Preceding gene: 53722386

Following gene: 53722384

Centisome position: 58.7

GC content: 67.66

Gene sequence:

>2214_bases
TTGCAAACGGCTTTCTGGCAAAGACACCTCGGAGGGGGCGAGATGGCGTCGGGCATCGGGCGATTCGGGAAAAGAGCGTC
GCGCTTGATCGATTTCGGTTTGTGGGCCGCCGCCGCGCTGTTACTGCTGACGGCGGGCGTCGGCGCGCTCGGCACGGCCC
GCCTGTCCGACAACGAGGCGGATATCCATCGCGCGAGCGAGGTGATATCGGGTCTCGAACGGCTGCTGGCGCTGGCCCGC
GACATGGAGACGAGCCAGCGCGGATATATCCTCACCGGCAAGCCGGACTACCTTCAGCCTTACAAGGCGGCACTGCCCGA
AATCCGCAAGCAGTTCGATGCGCTCACGACGCTCGTGCAGGACGATGCCGTTCAGCAGCAGCGGCTCGCGACGCTGCGCA
TGCTGCTCGAGAAAAAGCAGCACGAGCTCGCGGCGACGATCGAGCTGCGCAAGACGGAGGGGTTCGACGCGGCGCAGGCG
ATCGTCTCGAGCGATGCGGGCAAGATCTTCATGGACCGCGCGCGCGTGATGGTCAACGAAATGGAGGCGACCGTCCAGCA
GCAACTGAGGACGCTGCGCGATCGCGCCAGGGCGACACGCGACATCGCGATCGGCGTGGGGCTCGCGTCCGGGCTGCTCA
CGCTCGCCGTGTGCGTATCGTTCGGCTATGTGATGCGCCGCCTGCTGCTCGTCGAGGCGGCCGCGGCCCACGATCTGTTC
GAGCAGCGCGAACTGCTGCACGTAACGCTCGCGAGCATCGGCGACGGCGTGATCGCGACGGACGTCGGCGGCCGCATCAC
GTTCTTCAACCGGGTCGCCGAGGAGATGACGGCGCTTTGCGCCGATGCCGTCGTCGGTCAGCCGATCGAGCGGGTGCTGA
CTTTTCGGCATGCCGCGACGCAGCGGGTGATCGACAATCCGGCGCGCGTCGCGGTCGAGCGCAGGCGCACCGCGAGCTTG
CCTGCCCATACGCGCTTCGTCGGCCGCAGCGGCGGGGAATTGCCGGTGGACGGCAACGCCGCACCGACGTTCGACGCGAA
CGGCAAGCTCGTCGGCGCGGTGCTCGTCGTGCGCGACGTGTCGGAGCGCGAGCGGGCCGAGGAGCGATTCCGGCTCGCCG
TCGAGGCCGCGCCGACCGCGATGATCATGGTGGGGCGCGACGGCAGGATCGTGCTCGTCAATTCGCAGGCCGAGAAATTG
TTCGGGTACGCGCGCGGCGACATGATCGGGCACGGCATCGACATGCTGGTGCCCGAGCGTTTTCGTGCGGGGCATTGGGC
GCACCGCGACGCGTTCTTCGGCAACCCGGACGCGCGGCCGATGGGCGAGGGGCGGGACCTGTTCGGTTTGCGCCGCGACG
GCAGCGAGTTTCCGGTCGAGATCGGCCTGAATCCGATCACGACCTCGGAGGGCGCGTTCGTGCTGTGCTCGATCGCCGAC
ATCACCGCGCGCAAGCGCGCGGAACTCGAACTGCGCCGCAGAAGCGAGGAGCTTGCGCGCTCGAATCAGGATCTCGAGCA
GTTCGCCTACGTCGCGTCTCACGATCTGCAGGAGCCGTTGCGCGCGGTCGCGGGGCCCCTGCAATTGCTGCAGCGGCGAT
ACCAGGGGCAGCTCGACGCGCGGGCCGACGAGTTCATCGGGCACGCGGTGGATGGCGCGACGAGAATGCAGTCGCTGATC
GACGACCTGCTCAGCTATTCGCGCGTCGGGCGGCTCGAGGACGCGCGCCGGCCGGTCGACTGCGAGCACGTGCTGGACGA
GGCGCTGCGCAACCTGAGCGCGGCGATTCGCGAATCCGGCGCGCAGGTCACGCACGATCCGCTGCCGACCGTGCATGGCA
TCGAGGCACAGCTCGTGCTGCTGTTCCAGAATCTGATCGGCAACGCGATCAAGTTTCGCGGCAAGGACCGCGTCGCGCGG
ATTCATCTGGAAGCGCACACGCGCGACGACGCATGGCTGTTGCGCGTGCGCGACAACGGCATCGGGATCGATCCGCAGTA
TTTCGAGCGCATCTTCCTGATTTTCCAGCGGCTGCACACGCGGCGCGAATATCCGGGAACGGGGCTCGGGCTCGCGCTGT
GCAAGCGGATCGTCGAGCACCACGGCGGCCGCATCTTCGTCGAGTCCGAGCCGGGGCAGGGCACGACGTTTTCGTTTACG
CTGTCCAGGCCGGGTGCCGATGAAACGCGTTGGCCGCGCGATCCGAGGGAGTGA

Upstream 100 bases:

>100_bases
CCGCCCCGCACGACGGCGCGCTTCGCGCACGACGCGCGAGCGCCCGGCGTGCGCGCCGGCGCGCGGCGAGCCGGGCGGCG
GCCGCATCCCGCGATCAAGC

Downstream 100 bases:

>100_bases
GCGATGATTGCCGATGAGCGAGGAAATTTCGTCGAGATCCTGCTGGTCGAGGACAGCCCGACCGACGTGATGATGACCAA
GGAGGCGCTCGAATACTACA

Product: two-component sensor kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MQTAFWQRHLGGGEMASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLERLLALAR
DMETSQRGYILTGKPDYLQPYKAALPEIRKQFDALTTLVQDDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQA
IVSSDAGKIFMDRARVMVNEMEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLF
EQRELLHVTLASIGDGVIATDVGGRITFFNRVAEEMTALCADAVVGQPIERVLTFRHAATQRVIDNPARVAVERRRTASL
PAHTRFVGRSGGELPVDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKL
FGYARGDMIGHGIDMLVPERFRAGHWAHRDAFFGNPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIAD
ITARKRAELELRRRSEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGATRMQSLI
DDLLSYSRVGRLEDARRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVAR
IHLEAHTRDDAWLLRVRDNGIGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFT
LSRPGADETRWPRDPRE

Sequences:

>Translated_737_residues
MQTAFWQRHLGGGEMASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLERLLALAR
DMETSQRGYILTGKPDYLQPYKAALPEIRKQFDALTTLVQDDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQA
IVSSDAGKIFMDRARVMVNEMEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLF
EQRELLHVTLASIGDGVIATDVGGRITFFNRVAEEMTALCADAVVGQPIERVLTFRHAATQRVIDNPARVAVERRRTASL
PAHTRFVGRSGGELPVDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKL
FGYARGDMIGHGIDMLVPERFRAGHWAHRDAFFGNPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIAD
ITARKRAELELRRRSEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGATRMQSLI
DDLLSYSRVGRLEDARRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVAR
IHLEAHTRDDAWLLRVRDNGIGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFT
LSRPGADETRWPRDPRE
>Mature_737_residues
MQTAFWQRHLGGGEMASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLERLLALAR
DMETSQRGYILTGKPDYLQPYKAALPEIRKQFDALTTLVQDDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQA
IVSSDAGKIFMDRARVMVNEMEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLF
EQRELLHVTLASIGDGVIATDVGGRITFFNRVAEEMTALCADAVVGQPIERVLTFRHAATQRVIDNPARVAVERRRTASL
PAHTRFVGRSGGELPVDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKL
FGYARGDMIGHGIDMLVPERFRAGHWAHRDAFFGNPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIAD
ITARKRAELELRRRSEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGATRMQSLI
DDLLSYSRVGRLEDARRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVAR
IHLEAHTRDDAWLLRVRDNGIGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFT
LSRPGADETRWPRDPRE

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=28.8461538461538, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI48994928, Length=260, Percent_Identity=29.2307692307692, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=32.6446280991736, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=375, Percent_Identity=27.2, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=28.6852589641434, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=371, Percent_Identity=27.4932614555256, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=26.5560165975104, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=24.5210727969349, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1788381, Length=127, Percent_Identity=31.496062992126, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=28.5123966942149, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81630; Mature: 81630

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAFWQRHLGGGEMASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEA
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHH
DIHRASEVISGLERLLALARDMETSQRGYILTGKPDYLQPYKAALPEIRKQFDALTTLVQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQAIVSSDAGKIFMDRARVMVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
MEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQRELLHVTLASIGDGVIATDVGGRITFFNRVAEEMTALCADAVVGQPIERVLTFRHAAT
HHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QRVIDNPARVAVERRRTASLPAHTRFVGRSGGELPVDGNAAPTFDANGKLVGAVLVVRDV
HHHHCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCC
SERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGIDMLVPER
HHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCHHHCCHHHHCCHH
FRAGHWAHRDAFFGNPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIAD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEHH
ITARKRAELELRRRSEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RADEFIGHAVDGATRMQSLIDDLLSYSRVGRLEDARRPVDCEHVLDEALRNLSAAIRESG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
AQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVARIHLEAHTRDDAWLLRVRDNG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEECCC
IGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEE
LSRPGADETRWPRDPRE
ECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTAFWQRHLGGGEMASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEA
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHH
DIHRASEVISGLERLLALARDMETSQRGYILTGKPDYLQPYKAALPEIRKQFDALTTLVQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQAIVSSDAGKIFMDRARVMVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
MEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQRELLHVTLASIGDGVIATDVGGRITFFNRVAEEMTALCADAVVGQPIERVLTFRHAAT
HHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QRVIDNPARVAVERRRTASLPAHTRFVGRSGGELPVDGNAAPTFDANGKLVGAVLVVRDV
HHHHCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCC
SERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGIDMLVPER
HHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCHHHCCHHHHCCHH
FRAGHWAHRDAFFGNPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIAD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEHH
ITARKRAELELRRRSEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RADEFIGHAVDGATRMQSLIDDLLSYSRVGRLEDARRPVDCEHVLDEALRNLSAAIRESG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
AQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVARIHLEAHTRDDAWLLRVRDNG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEECCC
IGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEE
LSRPGADETRWPRDPRE
ECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]