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The map label for this gene is hycD [H]

Identifier: 53722174

GI number: 53722174

Start: 1532873

End: 1533823

Strand: Reverse

Name: hycD [H]

Synonym: BPSS1146

Alternate gene names: 53722174

Gene position: 1533823-1532873 (Counterclockwise)

Preceding gene: 53722175

Following gene: 53722173

Centisome position: 48.34

GC content: 69.61

Gene sequence:

>951_bases
ATGGTGAGCGCATCCGGCATCCTGTCGCAGACGCTCGAGATACTCGTCGCGCTCGCGGCCGCGCCGCTGTTGACCGGCTG
GGTCAACCAGTGCCGCGCGTGGCTGCAGAACCGCCGCGCGCCGAGCATCTGGCAGCCGTACCGGATGCTGCACAAGCTGT
TCAACAAGGAATCGGTGGTCGCGGAGCACGCGAGCCCGCTCTTTCGCGGCGCGCCGTACGTCGTCTGGGCGGCGATGGCG
CTCGCGTGCGCGATCGTGCCGACGCTGTCGACCGAGCTGCCGTTCTCGCCCGCGGCCGACGCGATCGCGCTCGTCGGCCT
GTTCGCGCTCGCGCGCGTCGCGCTCTCGCTCGCGGCGATGGACATCGGCACCGCGTTCGGCACGCTCGGCGCGCGCCGCG
AGATGCTGATCGGCTTCCTCGCGGAGCCGGCGCTCCTGATGGTGCTGTTCTCGGCGTCGCTGATCACGCGCTCGACGCTG
CTGACGAGCATCGTCGCCGCGCTCGGCCACCGCGAGCTCGCGATCTATCCGAGCCTCGCGTTCGCGGGCATCGCGTTCAC
GCTCGTGTCGCTCGCGGAGAACGCGCGGCTGCCGGTGGACAACCCCGCGACGCACCTCGAGCTGACGATGATCCACGAGG
CGCTGATCCTCGAATACTCGGGCCGCCATCTCGCGCTGATGGAATGGGCGGCAAGCCTGAAGCTCTTCGCGTATTCGTGC
ATCGGCCTCGCGCTCTTCATGCCGTGGGGCATCGCCGAGGCCGGCAGCCCGCTCGCGTTGCTGCTCGCGCTGCCGGCGCT
CTTCGTGAAGTTGCTCGTCGGCGGCGCGGCGCTGGCGGTGGTCGAGACGACGAACGCGAAAATGCGCCTCTTTCGCGTGC
CCGAATTCCTCGCGAGCGCGTTCCTGCTCGCGGTGATCGGCATGCTCGTCCATTTCCTGCTGGGGGCGTAG

Upstream 100 bases:

>100_bases
GCGTCGCCGCGCTCGTCGGGCGGTTGCAGACGGGCCGCATCGCGATCTATCTGACGTACAGCTTCATCGTGCTGATCGTC
CTTCTGACGGTGGTGAGACG

Downstream 100 bases:

>100_bases
ATGCACGGCTACGCGACGCAGCTCGTCAACTTCCTCGCGGCGATCCTGCTGCTGCTGTCGTTCGCGATGCTGAGCCAGCG
GCGGATCCTGTCGCTGATCC

Product: formate hydrogenlyase subunit 4

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MVSASGILSQTLEILVALAAAPLLTGWVNQCRAWLQNRRAPSIWQPYRMLHKLFNKESVVAEHASPLFRGAPYVVWAAMA
LACAIVPTLSTELPFSPAADAIALVGLFALARVALSLAAMDIGTAFGTLGARREMLIGFLAEPALLMVLFSASLITRSTL
LTSIVAALGHRELAIYPSLAFAGIAFTLVSLAENARLPVDNPATHLELTMIHEALILEYSGRHLALMEWAASLKLFAYSC
IGLALFMPWGIAEAGSPLALLLALPALFVKLLVGGAALAVVETTNAKMRLFRVPEFLASAFLLAVIGMLVHFLLGA

Sequences:

>Translated_316_residues
MVSASGILSQTLEILVALAAAPLLTGWVNQCRAWLQNRRAPSIWQPYRMLHKLFNKESVVAEHASPLFRGAPYVVWAAMA
LACAIVPTLSTELPFSPAADAIALVGLFALARVALSLAAMDIGTAFGTLGARREMLIGFLAEPALLMVLFSASLITRSTL
LTSIVAALGHRELAIYPSLAFAGIAFTLVSLAENARLPVDNPATHLELTMIHEALILEYSGRHLALMEWAASLKLFAYSC
IGLALFMPWGIAEAGSPLALLLALPALFVKLLVGGAALAVVETTNAKMRLFRVPEFLASAFLLAVIGMLVHFLLGA
>Mature_316_residues
MVSASGILSQTLEILVALAAAPLLTGWVNQCRAWLQNRRAPSIWQPYRMLHKLFNKESVVAEHASPLFRGAPYVVWAAMA
LACAIVPTLSTELPFSPAADAIALVGLFALARVALSLAAMDIGTAFGTLGARREMLIGFLAEPALLMVLFSASLITRSTL
LTSIVAALGHRELAIYPSLAFAGIAFTLVSLAENARLPVDNPATHLELTMIHEALILEYSGRHLALMEWAASLKLFAYSC
IGLALFMPWGIAEAGSPLALLLALPALFVKLLVGGAALAVVETTNAKMRLFRVPEFLASAFLLAVIGMLVHFLLGA

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=295, Percent_Identity=33.8983050847458, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87082115, Length=244, Percent_Identity=33.6065573770492, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 33684; Mature: 33684

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSASGILSQTLEILVALAAAPLLTGWVNQCRAWLQNRRAPSIWQPYRMLHKLFNKESVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHH
AEHASPLFRGAPYVVWAAMALACAIVPTLSTELPFSPAADAIALVGLFALARVALSLAAM
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIGTAFGTLGARREMLIGFLAEPALLMVLFSASLITRSTLLTSIVAALGHRELAIYPSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHH
FAGIAFTLVSLAENARLPVDNPATHLELTMIHEALILEYSGRHLALMEWAASLKLFAYSC
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IGLALFMPWGIAEAGSPLALLLALPALFVKLLVGGAALAVVETTNAKMRLFRVPEFLASA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEEEECCCHHEEHHHHHHHHHH
FLLAVIGMLVHFLLGA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSASGILSQTLEILVALAAAPLLTGWVNQCRAWLQNRRAPSIWQPYRMLHKLFNKESVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHH
AEHASPLFRGAPYVVWAAMALACAIVPTLSTELPFSPAADAIALVGLFALARVALSLAAM
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIGTAFGTLGARREMLIGFLAEPALLMVLFSASLITRSTLLTSIVAALGHRELAIYPSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHH
FAGIAFTLVSLAENARLPVDNPATHLELTMIHEALILEYSGRHLALMEWAASLKLFAYSC
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IGLALFMPWGIAEAGSPLALLLALPALFVKLLVGGAALAVVETTNAKMRLFRVPEFLASA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEEEECCCHHEEHHHHHHHHHH
FLLAVIGMLVHFLLGA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]