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The map label for this gene is fadH

Identifier: 53722161

GI number: 53722161

Start: 1518650

End: 1520671

Strand: Reverse

Name: fadH

Synonym: BPSS1133

Alternate gene names: 53722161

Gene position: 1520671-1518650 (Counterclockwise)

Preceding gene: 53722166

Following gene: 53722160

Centisome position: 47.93

GC content: 69.24

Gene sequence:

>2022_bases
ATGACCTTCTATCCCCACCTGACGGCTCCGCTGGAGCTCGGTTTCACTTCGTTGAAGAACCGCGTGTTGATGGGCTCGAT
GCATGTCGGGCTCGAGGAGGCGGCAAACGGCTTCGAGCGGATGGCCGCGTTCTACGCCGAGCGCGCGCGCGGCGAGGCCG
GGCTCATCGTCACGGGCGGCATCGCGCCGAACGAGCGCGGCCGGATGATGCCCGGCGGCTCGATGCTCACGACCGAGGAG
GAGGCCGAGCGCCATCGGATCGTCACGCGCGCGGTGCACGACGCCGGCGGCAGGATCGCGATGCAGATCCTGCACTTCGG
CCGCTACGCCTATCATCCGGCGCTCGTCGCGCCGAGCGCGCTGAAGGCGCCGATCAATACGTTCACGCCGCATGCGCTGT
CCGCGAGCGAGGTCGACGCGACGATCGACGATTTCGCGCGCTGCGCGGCGCTCGCGCAATACGCGGGCTACGACGGCGTC
GAGATCATGGGCTCCGAAGGCTATCTGATCAACGAATTCATCGCCGCGCACACGAACCATCGCGAAGACGAATGGGGCGG
CGCGTACGAAAACCGCATCCGCTTTCCGGTCGAGATCGTGCGGCGCGTGCGCGAGCGGGTGGGCACGAATTTCATCATCA
TTTACCGGCTGTCGATGCTCGATCTCGTCGAAGGCGGCTCGACGCTCGACGAGGTGATCCGGCTCGCGCAGGCCATCGAG
GCGGCCGGCGCGACGATTCTGAACACCGGCATCGGCTGGCACGAGGCGCGCATTCCGACGATCGCGACGAAGGTGCCGCG
CGCCGCGTATGCGTGGGTGACGAAGCGGCTCGTCGGCCGGGTCGGCATTCCGCTCGTCGCGACGAACCGGATCAACACGC
CCGAGATCGCCGAGCAACTGCTCGCCGAAGGCTATTGCGACATGGTGTCGATGGCGCGGCCGTTCCTCGCCGATGCGCAG
TTCGTGCGCAAGGCGCGCGAAGGGCGCGCCGACGAGATCAACACCTGCATCGGCTGCAACCAGGCGTGCCTCGATCACAT
CTTCAGCGGCCGAATCACGTCGTGCCTCGTCAATCCGCGCGCGTGCCACGAGACCGAGCTCGTGATCGAGCCGGCCGAAC
GGCGCAAGCGGATCGCGGTCGTCGGCGCGGGGCCGGCCGGCTTGAGCTTCGCCGTCACGGCCGCCGAGCGCGGGCACGAC
GTCGAGCTGTTCGAAGCGTCGCCGGAGATCGGCGGGCAGTTCAACATCGCGAAGAAGGTGCCCGGCAAGGAGGAGTTTCA
CGAGACGCTGCGCTATTTCCGCCGGCAGCTCGAGTTGCGCGGCGTGACGCTGCACCTGAACACGCGGGCGGACGTCGCGC
GGCTCGCCGGCGGCGGCTTCGACGAGATCGTGCTCGCGACGGGCGTGACGCCGCGCCGGCCCGACATAGAAGGCATCGGC
CACGCGCGCGTGATGGGCTACCTCGACGTGCTGCGCGACGGCAAGCCGGTGGGCGCGAGCGTGGCCGTGATCGGCGCGGG
CGGGATCGGCTTCGACGTCAGTGAATACCTGACGCACACGGGCGAGAGCGCGAGCGTGGCGCCGTCGACGTTCTATGCGC
AATGGGGCATCGACATCGACTACGGCGCGCGCGGCGGCGTGCGGATGCCGCACGTCGAGGCCGCGCCGCGCAACGTGCAT
CTGCTGCAGCGCAAGGCGTCGAAGGTCGGCGATGGGCTCGGCAAGACGACGGGCTGGATCCATCGGACGTCGCTGAAGGC
GCGGCGCGTCGCGATGTCGTCCGGCGTATCGTACGAGCGGATCGACGACGCGGGGCTGCACGTGCGCATCGACGGCGAGC
CGCGCACGCTCGCGGTCGACAGCGTCGTCGTCTGCGCGGGCCAGGAGCCGCAGCGCGAGCTGTACGACGGCCTGCGCGCG
GCCGGCTGTTCGGTGCACCTGATCGGCGGCGCGCACGTTGCCGCGGAACTCGACGCGAAGCGCGCGATCCTGCAGGGCAC
GACGCTCGCCGCTTCGATCTGA

Upstream 100 bases:

>100_bases
CGCGCGCGCCCGTTTAGAGGGCGCACTTTATGCAACGCGTTGCATTTGAGGAGGGGCGTCGCTATATTTGTGCAACCCGT
TGCATAAAAAAGAGCGCCCG

Downstream 100 bases:

>100_bases
CGCATGCGGCTCGCCGCGCTTGGCGATGCATGGGCATGCGGCTTCGCGCCGCGCAATCCCTGCCCGTTCCCGATTTGACC
GACAAGGAGATACAACATGA

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MTFYPHLTAPLELGFTSLKNRVLMGSMHVGLEEAANGFERMAAFYAERARGEAGLIVTGGIAPNERGRMMPGGSMLTTEE
EAERHRIVTRAVHDAGGRIAMQILHFGRYAYHPALVAPSALKAPINTFTPHALSASEVDATIDDFARCAALAQYAGYDGV
EIMGSEGYLINEFIAAHTNHREDEWGGAYENRIRFPVEIVRRVRERVGTNFIIIYRLSMLDLVEGGSTLDEVIRLAQAIE
AAGATILNTGIGWHEARIPTIATKVPRAAYAWVTKRLVGRVGIPLVATNRINTPEIAEQLLAEGYCDMVSMARPFLADAQ
FVRKAREGRADEINTCIGCNQACLDHIFSGRITSCLVNPRACHETELVIEPAERRKRIAVVGAGPAGLSFAVTAAERGHD
VELFEASPEIGGQFNIAKKVPGKEEFHETLRYFRRQLELRGVTLHLNTRADVARLAGGGFDEIVLATGVTPRRPDIEGIG
HARVMGYLDVLRDGKPVGASVAVIGAGGIGFDVSEYLTHTGESASVAPSTFYAQWGIDIDYGARGGVRMPHVEAAPRNVH
LLQRKASKVGDGLGKTTGWIHRTSLKARRVAMSSGVSYERIDDAGLHVRIDGEPRTLAVDSVVVCAGQEPQRELYDGLRA
AGCSVHLIGGAHVAAELDAKRAILQGTTLAASI

Sequences:

>Translated_673_residues
MTFYPHLTAPLELGFTSLKNRVLMGSMHVGLEEAANGFERMAAFYAERARGEAGLIVTGGIAPNERGRMMPGGSMLTTEE
EAERHRIVTRAVHDAGGRIAMQILHFGRYAYHPALVAPSALKAPINTFTPHALSASEVDATIDDFARCAALAQYAGYDGV
EIMGSEGYLINEFIAAHTNHREDEWGGAYENRIRFPVEIVRRVRERVGTNFIIIYRLSMLDLVEGGSTLDEVIRLAQAIE
AAGATILNTGIGWHEARIPTIATKVPRAAYAWVTKRLVGRVGIPLVATNRINTPEIAEQLLAEGYCDMVSMARPFLADAQ
FVRKAREGRADEINTCIGCNQACLDHIFSGRITSCLVNPRACHETELVIEPAERRKRIAVVGAGPAGLSFAVTAAERGHD
VELFEASPEIGGQFNIAKKVPGKEEFHETLRYFRRQLELRGVTLHLNTRADVARLAGGGFDEIVLATGVTPRRPDIEGIG
HARVMGYLDVLRDGKPVGASVAVIGAGGIGFDVSEYLTHTGESASVAPSTFYAQWGIDIDYGARGGVRMPHVEAAPRNVH
LLQRKASKVGDGLGKTTGWIHRTSLKARRVAMSSGVSYERIDDAGLHVRIDGEPRTLAVDSVVVCAGQEPQRELYDGLRA
AGCSVHLIGGAHVAAELDAKRAILQGTTLAASI
>Mature_672_residues
TFYPHLTAPLELGFTSLKNRVLMGSMHVGLEEAANGFERMAAFYAERARGEAGLIVTGGIAPNERGRMMPGGSMLTTEEE
AERHRIVTRAVHDAGGRIAMQILHFGRYAYHPALVAPSALKAPINTFTPHALSASEVDATIDDFARCAALAQYAGYDGVE
IMGSEGYLINEFIAAHTNHREDEWGGAYENRIRFPVEIVRRVRERVGTNFIIIYRLSMLDLVEGGSTLDEVIRLAQAIEA
AGATILNTGIGWHEARIPTIATKVPRAAYAWVTKRLVGRVGIPLVATNRINTPEIAEQLLAEGYCDMVSMARPFLADAQF
VRKAREGRADEINTCIGCNQACLDHIFSGRITSCLVNPRACHETELVIEPAERRKRIAVVGAGPAGLSFAVTAAERGHDV
ELFEASPEIGGQFNIAKKVPGKEEFHETLRYFRRQLELRGVTLHLNTRADVARLAGGGFDEIVLATGVTPRRPDIEGIGH
ARVMGYLDVLRDGKPVGASVAVIGAGGIGFDVSEYLTHTGESASVAPSTFYAQWGIDIDYGARGGVRMPHVEAAPRNVHL
LQRKASKVGDGLGKTTGWIHRTSLKARRVAMSSGVSYERIDDAGLHVRIDGEPRTLAVDSVVVCAGQEPQRELYDGLRAA
GCSVHLIGGAHVAAELDAKRAILQGTTLAASI

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=672, Percent_Identity=64.2857142857143, Blast_Score=882, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=351, Percent_Identity=28.4900284900285, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=228, Percent_Identity=27.1929824561404, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=220, Percent_Identity=26.3636363636364, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=229, Percent_Identity=27.5109170305677, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=309, Percent_Identity=23.9482200647249, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17566914, Length=215, Percent_Identity=29.7674418604651, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565138, Length=240, Percent_Identity=26.25, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=221, Percent_Identity=27.6018099547511, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=228, Percent_Identity=28.9473684210526, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=223, Percent_Identity=26.9058295964126, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72760; Mature: 72629

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFYPHLTAPLELGFTSLKNRVLMGSMHVGLEEAANGFERMAAFYAERARGEAGLIVTGG
CCCCCCCCCHHHHCHHHHCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
IAPNERGRMMPGGSMLTTEEEAERHRIVTRAVHDAGGRIAMQILHFGRYAYHPALVAPSA
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHCCCHH
LKAPINTFTPHALSASEVDATIDDFARCAALAQYAGYDGVEIMGSEGYLINEFIAAHTNH
HHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCC
REDEWGGAYENRIRFPVEIVRRVRERVGTNFIIIYRLSMLDLVEGGSTLDEVIRLAQAIE
CCCCCCCHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHHH
AAGATILNTGIGWHEARIPTIATKVPRAAYAWVTKRLVGRVGIPLVATNRINTPEIAEQL
HCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHH
LAEGYCDMVSMARPFLADAQFVRKAREGRADEINTCIGCNQACLDHIFSGRITSCLVNPR
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCHHHHCCCCC
ACHETELVIEPAERRKRIAVVGAGPAGLSFAVTAAERGHDVELFEASPEIGGQFNIAKKV
CCCCCEEEECCHHCCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEECCCC
PGKEEFHETLRYFRRQLELRGVTLHLNTRADVARLAGGGFDEIVLATGVTPRRPDIEGIG
CCHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHCCCCCCCEEEECCCCCCCCCCCCCC
HARVMGYLDVLRDGKPVGASVAVIGAGGIGFDVSEYLTHTGESASVAPSTFYAQWGIDID
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCEEC
YGARGGVRMPHVEAAPRNVHLLQRKASKVGDGLGKTTGWIHRTSLKARRVAMSSGVSYER
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEE
IDDAGLHVRIDGEPRTLAVDSVVVCAGQEPQRELYDGLRAAGCSVHLIGGAHVAAELDAK
ECCCCCEEEECCCCCEEEECEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEHHHHHH
RAILQGTTLAASI
HHHHCCCCCEECC
>Mature Secondary Structure 
TFYPHLTAPLELGFTSLKNRVLMGSMHVGLEEAANGFERMAAFYAERARGEAGLIVTGG
CCCCCCCCHHHHCHHHHCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
IAPNERGRMMPGGSMLTTEEEAERHRIVTRAVHDAGGRIAMQILHFGRYAYHPALVAPSA
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHCCCHH
LKAPINTFTPHALSASEVDATIDDFARCAALAQYAGYDGVEIMGSEGYLINEFIAAHTNH
HHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCC
REDEWGGAYENRIRFPVEIVRRVRERVGTNFIIIYRLSMLDLVEGGSTLDEVIRLAQAIE
CCCCCCCHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHHH
AAGATILNTGIGWHEARIPTIATKVPRAAYAWVTKRLVGRVGIPLVATNRINTPEIAEQL
HCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHH
LAEGYCDMVSMARPFLADAQFVRKAREGRADEINTCIGCNQACLDHIFSGRITSCLVNPR
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCHHHHCCCCC
ACHETELVIEPAERRKRIAVVGAGPAGLSFAVTAAERGHDVELFEASPEIGGQFNIAKKV
CCCCCEEEECCHHCCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCEEECCCC
PGKEEFHETLRYFRRQLELRGVTLHLNTRADVARLAGGGFDEIVLATGVTPRRPDIEGIG
CCHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHCCCCCCCEEEECCCCCCCCCCCCCC
HARVMGYLDVLRDGKPVGASVAVIGAGGIGFDVSEYLTHTGESASVAPSTFYAQWGIDID
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCEEC
YGARGGVRMPHVEAAPRNVHLLQRKASKVGDGLGKTTGWIHRTSLKARRVAMSSGVSYER
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEE
IDDAGLHVRIDGEPRTLAVDSVVVCAGQEPQRELYDGLRAAGCSVHLIGGAHVAAELDAK
ECCCCCEEEECCCCCEEEECEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEHHHHHH
RAILQGTTLAASI
HHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]