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The map label for this gene is chaA [C]

Identifier: 53722037

GI number: 53722037

Start: 1388785

End: 1389927

Strand: Reverse

Name: chaA [C]

Synonym: BPSS1016

Alternate gene names: 53722037

Gene position: 1389927-1388785 (Counterclockwise)

Preceding gene: 53722039

Following gene: 53722035

Centisome position: 43.8

GC content: 70.95

Gene sequence:

>1143_bases
GTGCCGGACCGCCTGTTAGAATCGCTGCTCGCGCCCTGCCACGACCAAGGACACTCCATGCCGATCTCTTCGTCCGCCCT
GCCGCGCTGGACGCTCGTCGCCCCGCTCGCCGCCTGGCTGGTGCTCGCGCTGTCGCGCGTCGTGCCGGCCGAAGGCTTCG
CCATCGCATTCGTCGCCGCCGCGCTCGCGGGCGCGGTGTTCTCCGCGGTGCATCACGCCGAAGTCGTCGCGCACCGCGTC
GGCGAGCCGTTCGGCACGCTCGTGCTCGCGATCGCCGTCACCGTGATCGAGGTCGCGCTGATCGTCTCGGTGATGCTGTC
GGCCGGCCCCGAGAAAGCGGGGCTCGCGCGCGACACCGTGTTCGCCGCGGTGATGATCGTCTGCAACGGGATCGTCGGGC
TGTGCCTGCTCGTCGGCGGCTGGCGGCACGGCGAGCAGGACTTCCAGGGGCGCGGCGCGACGAAGGCGCTCGCGGTGCTC
GCGTCGCTGTCGGTGCTCTCGCTCGTGATGCCGAACTATCTGAGCGCCGCGCCGGGCCCACGGCTGTCGACGTCGCAGCT
CGCGTTCGCGGGCGTGTCCTCGCTCGTGCTGTACGGCGTGTTCGTGTTCGTGCAGACGGTTCGCCATCGCGATTACTTCC
TGATCGACGGCAGCGCCGACGAATCCGTCCATGCGGTGCCGCCGAGCGGCCGCACCGCGCTCACGAGCATCGCGTTCCTG
TTCGTGAGCCTCGTCGCGGTCGTGCTGCTCGCGAAGCTGCTGTCGCCCGCCGTCGAGCGCACGGTGCTGCGGCTCGGCGC
GCCCGAGGCGGCCGTCGGCATCGTGATCGCCGCGCTCGTGCTGCTGCCGGAAGGGCTCGCCGCCGTCGGCGCGGCGCGCG
CGAACCGGCTGCAGACGAGCATGAACCTCGCGCTCGGCTCAGCGCTCGCGAGCATCGGCCTGACGATTCCGACCGTCGCC
GCCGTGTTCATCTGGACGGGCGCGCCGCTCACGCTCGGCATCGGCGCAATGGAGACGGTGCTGCTGTCGCTCACGCTGCT
CGTCAGCACGCTCACGCTCAGCCTGGGACGCACGACGGTGCTGCACGGCGTCGTGCATCTGTCGCTGTTCGCCGCCTATC
TGTTCCTGTCGATCACGCACTGA

Upstream 100 bases:

>100_bases
CCGCGACCATCGGCGGGGCCTCGACGGCCGCGCGGCGTCGCGCTTGCGCGCGTCCGCCGGCCGCTGCCCGCGGCGGCGCG
CGGCGGCGCGCGGGATTTCG

Downstream 100 bases:

>100_bases
CCACGCAACCGGCGCGCCGGCGCACGCGCCGTGTTGTGCTTCCCGCCCGCCGGCGCCGCGCGCGGCCCGTCCTCGTCGGA
CTTTCGACATCGGGCAGCGC

Product: ionic antiporter

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MPDRLLESLLAPCHDQGHSMPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRV
GEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVL
ASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFL
FVSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVA
AVFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSITH

Sequences:

>Translated_380_residues
MPDRLLESLLAPCHDQGHSMPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRV
GEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVL
ASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFL
FVSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVA
AVFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSITH
>Mature_379_residues
PDRLLESLLAPCHDQGHSMPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVG
EPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVLA
SLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFLF
VSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAA
VFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSITH

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=353, Percent_Identity=37.3937677053824, Blast_Score=201, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 39198; Mature: 39067

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRLLESLLAPCHDQGHSMPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAA
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALAGAVFSAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
FAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVLASLSVLSLVMPNYLSAAPGP
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHH
FVSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MNLALGSALASIGLTIPTVAAVFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGVVHLSLFAAYLFLSITH
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDRLLESLLAPCHDQGHSMPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAA
CHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALAGAVFSAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
FAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVLASLSVLSLVMPNYLSAAPGP
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHH
FVSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MNLALGSALASIGLTIPTVAAVFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGVVHLSLFAAYLFLSITH
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]