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The map label for this gene is napA [H]

Identifier: 53722026

GI number: 53722026

Start: 1326251

End: 1327483

Strand: Reverse

Name: napA [H]

Synonym: BPSS1005

Alternate gene names: 53722026

Gene position: 1327483-1326251 (Counterclockwise)

Preceding gene: 53722033

Following gene: 53722025

Centisome position: 41.84

GC content: 66.59

Gene sequence:

>1233_bases
ATGAACAGCATCTTCGTCTTCCTGTCGCAGGCCCTGCTGATCGTCGCAGTGCCGCCATTGCTGATGAACTACCTGCGCGT
CGGGGCGGTCGTGCCGCTCGTCGTCGTGCAGATCGTGTTCGGCGTCGTGATCGGCCCGTCGGGCCTCGGACGCCTGTCGC
CCGAAACCTATACGGCGCTCTTTCCTCCCGATTCGCTGACGTTCCTGTCGCACGTCTCGGCGATCGCGCTGTTCTTCTTC
GCGATCGTCACCGGCCTGCATCTCGACGCCACGGCGCTGCGGGGCCACGGCCGCAAGCTCGGCTTCATCTCGACGGCGAG
CATGCTCGCGCCGATGTCGCTCGGCGTGCTCGCGGGGATCGCGATCAGCGCGCGATACCCGCAAGCGCTCGATCCGCATG
CGTCCGTCGCCGAATTCGTCGCCGGCATCGGCATCTGCTGCGGCGTGACCGCGCTGCCCGTTCTCGCGGCGATCCTGCGC
GAGACGAACCTCACCTCGCGCCGCCTCGGACAGTTCTCGCTCGCGCTCGCCGCGGTCAACGACGGCATGCTGTGGATTCT
GCTCGCCGCGTTCCTCTCGGTGACGGGCGCGAACGCGGCGAACGGCGGCAGACTTTTCATTACCTCGGCTCTCATCGTGC
TGTATTTCGTGTCGATCCTGTTCGTCGTGCGTCCGTTGCTGCTCGTGCTGGCGAACCGGCTCCGGACGTCCGTCGATACG
CAAATCCTCATCGCATGCGCCGTGGCCGTCGCGTCGGCCGCCGCCACCGACCGCCTCGGCCTGCACTACCTGCTCGGCGC
GTTCATCGCCGGCGCGATCATCCCCGGCGCATGGCGCGACGCCTTGCTCGAACGCATGCAGCCGGTCACCGTCAACGTCC
TCACCCCGTTCTTTTTCATCAGCACCGGGTTGCGCGTGCTGATCGACGTCGACGCCCCGGGCTTTCTGCAGATCACGCTG
ATCATCACGCTCTGCACCGCGATCGGAAAAATCGCCGGCACCACGCTCGCGGCCCGCATGACCGGCGAATCCTGGGGATT
CTGTCTCGGGCTCGGGTTCCTCGCCCAGGCCAAGGGGCTGATGGAACTCGTCGTCGCGACGATCCTGCTCGACTCTCACG
TGATCTCGCGCACCGTGTTCTCCGCGCTGATCCTGATGGCGCTGATCAGCACGGCTTTCGCGATGCCGCTGCTGCGATTG
AAACCGGTGCGCGGCGCGGCGCTGTCCGCGTGA

Upstream 100 bases:

>100_bases
AGCGGCCGGAAGAACGGCGGGCGCGCCACGGCCACGGCCGCGGCTGCGGCCGCGCGAAAGAAACGACGTTGCCCGCGCAA
CAACATCAACGGGAGTAAGC

Downstream 100 bases:

>100_bases
CACGCGCGGGCCTCGCGCCGCTTCGCCGGGGTTCGGGGCACCGCGAAAACCGGCGAATTCGCCATATTTCGGCCAAGTAT
ATCGATAGCATTTCGGCGTC

Product: sodium/hydrogen exchanger family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTALFPPDSLTFLSHVSAIALFFF
AIVTGLHLDATALRGHGRKLGFISTASMLAPMSLGVLAGIAISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILR
ETNLTSRRLGQFSLALAAVNDGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDT
QILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFISTGLRVLIDVDAPGFLQITL
IITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGLMELVVATILLDSHVISRTVFSALILMALISTAFAMPLLRL
KPVRGAALSA

Sequences:

>Translated_410_residues
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTALFPPDSLTFLSHVSAIALFFF
AIVTGLHLDATALRGHGRKLGFISTASMLAPMSLGVLAGIAISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILR
ETNLTSRRLGQFSLALAAVNDGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDT
QILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFISTGLRVLIDVDAPGFLQITL
IITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGLMELVVATILLDSHVISRTVFSALILMALISTAFAMPLLRL
KPVRGAALSA
>Mature_410_residues
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTALFPPDSLTFLSHVSAIALFFF
AIVTGLHLDATALRGHGRKLGFISTASMLAPMSLGVLAGIAISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILR
ETNLTSRRLGQFSLALAAVNDGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDT
QILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFISTGLRVLIDVDAPGFLQITL
IITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGLMELVVATILLDSHVISRTVFSALILMALISTAFAMPLLRL
KPVRGAALSA

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=411, Percent_Identity=31.3868613138686, Blast_Score=151, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 43017; Mature: 43017

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
FPPDSLTFLSHVSAIALFFFAIVTGLHLDATALRGHGRKLGFISTASMLAPMSLGVLAGI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
AISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILRETNLTSRRLGQFSLALAAVN
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
DGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDT
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHH
STGLRVLIDVDAPGFLQITLIITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGL
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHH
MELVVATILLDSHVISRTVFSALILMALISTAFAMPLLRLKPVRGAALSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
FPPDSLTFLSHVSAIALFFFAIVTGLHLDATALRGHGRKLGFISTASMLAPMSLGVLAGI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
AISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILRETNLTSRRLGQFSLALAAVN
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
DGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDT
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHH
STGLRVLIDVDAPGFLQITLIITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGL
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHH
MELVVATILLDSHVISRTVFSALILMALISTAFAMPLLRLKPVRGAALSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]