| Definition | Burkholderia pseudomallei K96243 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_006351 |
| Length | 3,173,005 |
Click here to switch to the map view.
The map label for this gene is pbpC [H]
Identifier: 53721842
GI number: 53721842
Start: 1092521
End: 1095061
Strand: Reverse
Name: pbpC [H]
Synonym: BPSS0816
Alternate gene names: 53721842
Gene position: 1095061-1092521 (Counterclockwise)
Preceding gene: 53721843
Following gene: 53721837
Centisome position: 34.51
GC content: 74.58
Gene sequence:
>2541_bases GTGTTCGGTTCGGCGTTCGGTTCGGCGTTCGCGGCGTTCGGTCTCGCGCTCGCCCCCCTGCTCGCCGCGCCGCCCGTTCG GCCGCGCGCCCGGCGAAACCCGCGCCCGTGCGGCTCGCCGCGGCGCGCGGCGCTCCCGCGCGCGCGAACGGCGGCGAGCC GCACGCTCGCCGTCGCGATGCTCGCCGCGCCGCTCGCCGCGCACGCGCTGCCGGCCTACGACGACGTGCGGCGCGACTGG CGCAGCACCGACTGGTTGCTGCTCGCACGCGACGGCACGCCGCTTCAGCGCACGCGCGTGGAGCTCACCGAGCGGCGCGG CGACTGGATCGCGCTCGCCGACGTATCGCCCGCGTTTCGAGAGGCGATCGTCGTATCGGAGGACAAGCGCTTCTACGCGC ACAGCGGCGTCGACTGGCGCGGCATCGCGGGCGCCGCATGGGGCAATCTGTGGAACGAGCGCACGCGCGGCGCGTCGACG GTGACGATGCAGCTCGCCGGCCTGCTGAGCGACACGCCGCGCCGCTCGGGCCAGCGCTCGCTGCCGCAGAAGGCCGCGCA GGCGATGAACGCGCTGCGGCTCGAACGCGGCTGGCGCAAGGATCAGATCCTCGAGGCGTATCTGAATCTCGTGCCGTTTC GCGGCGAGACGGTCGGGCTCGACGCGATGTCGCACGCGCTGTTCGGCAAGGCGCCGTCGGGGCTCGACGTGCGCGAATCG GCGGTGGCCGCCGCGCTCGTGCGCGCGCCGAACGCGTCCGCCGCGAAAGTGGCCGAACGCGCGTGCCGGATCCTGCGCGA CCTGCGCGCCGCGCAACCGTGCGAATCGCTCGACGGCTACGTGCGCTTCGTGACGTCCGCCCCGCCGGGCGCCGCGCGCG ACGGCGGCGAAGCGCTCGCGCCGCACTTCGCGCGGCGCGTCGCGGCCGAGGTGAAGCCCGGCGCGGGCGCGCGCGTGCGC TCCACGCTCGACGCGCCGCTGCAGCGCTTCGCGCGCGACACGCTCACGCGCGCGCTCGCCGAGCTCAACGCGCCCGCCCA TCGGCGCCACGTGCAGGACGGCGCGGTCGTCGTGATCGACAACGCGACGGGCGAGATCCGCGCATGGGTCGGCTCGTCGG GCGCGCTGTCGGCCGCGCGCGACGTCGACGCGGTGCTCGCGCCGCGCCAGGCCGGCTCGACGCTCAAGCCGTTCCTCTAC GCGCAGGCGCTCGACGAACGGCGCCTCACCGCCGCTTCGCTGCTCGACGACGCGCCGATCGATCTCGCCGCGGGCGGCGG CCTGTACATCCCGCAGAACTACGACAAGCACTTCAAGGGCTGGGTCAGCGTGCGCACCGCGCTCGGCGGATCGCTGAACG TGCCGGCCGTGCGCACGCTCGTGCTCGTCACGCCGCACCGCTTCGCGCGCACGCTCACCGCGCTCGGGCTGCCGCTCGCC GAAGAAGGCGATTACTACGGTTTCAGCCTCGCGCTCGGCAGCGCCGACGTCACGCTGCTGTCGCTCGCGAACGCGTACCG CGCGCTCGCCAACGGCGGCGTCGCGCGGGCGACGCTCGACGTGCCGGGCGGAAGCGGAAGCGGAAGCCGGAACGGAAACG GAAATGACGCCGTCACGTCGGCCCCGTTCGCGCCGGCCGTTTCGAAATCAAAGGTTGGCGCGTCAGCGGTTTTCCCGCGG GCCGTCTCGACGAAGGCCGAGCCCGCGAAGCCAGTGCCCACGGCGGCCCTTTCTCCCACGAGCGCTTCGACATCGACCGC CGGCAAGCCGGCGGCGCACGCCGCAGCGGGCACGCGCGTATTCAGCGAAGCCGCGGCGTACATCGTCACCGACATCCTCG CCGACAACAACGCGCGCGTGCGCACGTTCGGCTTCGACAGCCCGCTCGCGACGCGCTTCTTCTCCGCCGTCAAGACGGGC ACGAGCAAGGACATGCGCGACAACTGGGCGCTCGGCTACACGTCGCGCTACACGGTGGGCGTGTGGGTGGGCAACGCGGA CGGCTCGCCGATGTGGGACGTATCGGGCGTCACGGGCGCGGCGCCCGTGTGGGCCGCGATCGTCGGCTATCTGCACCGCG ATCTCGCGAGCCGCGCGCCGCGCCCGCCCGCCGGCGTCGAGCAGCGCCGCGTCGCGTTCGAACGCGACGTCGAGCCCGCG CGCCCCGAGTGGTTCATCGCCGGCACCGCGCTCGACACGGTGCGCCTCGCCGCGCCCGCGACCGCCGCCGCGGGCGGCGC AGACCGGCCGCGCGCGCCGCTTTCGATCGGCGCGCCGACCGACGGCACGATCTTCGCGATCGATCCGGACATCCCGCCGA AGCACCAGCGAATCTGGTTCGAGCGCGCGGCGGGGCGCGCGGCGCGCTTCTCGTGGCGGCTCGACGGCAAGGTGATCGGC CGCGGCGAGCGCCTCGCGTGGATGCCGTGGCCGGGATCGCACCGGCTCGAGCTCGTCGACGCGCGCGGCAACGTCGCCGA CGCGGTCGGCTTCGAGGTGCGCGGCGCGTTCGCGAAGACGGCGGCCCCACCGAAGCCGTGA
Upstream 100 bases:
>100_bases TTCGGTGTTCGGTCCGGCGTTCGGTCCGGCGTTCGGTCCGGCGTTCGGTCCGGCGTTCGGTTCGGCGTTCGGTCCGGCGT TCGGTTCGGCGTTCGGTTCG
Downstream 100 bases:
>100_bases GACGGCCCGCGCGCGCCGCCCAAGCGGCGCGCGCTCACAGCGCATCGAGAAACTGTTCGAGCGCCGCCTTCATCTTGTGG ATCGCCGCATCCGGCAACAG
Product: penicillin-binding protein
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 846; Mature: 846
Protein sequence:
>846_residues MFGSAFGSAFAAFGLALAPLLAAPPVRPRARRNPRPCGSPRRAALPRARTAASRTLAVAMLAAPLAAHALPAYDDVRRDW RSTDWLLLARDGTPLQRTRVELTERRGDWIALADVSPAFREAIVVSEDKRFYAHSGVDWRGIAGAAWGNLWNERTRGAST VTMQLAGLLSDTPRRSGQRSLPQKAAQAMNALRLERGWRKDQILEAYLNLVPFRGETVGLDAMSHALFGKAPSGLDVRES AVAAALVRAPNASAAKVAERACRILRDLRAAQPCESLDGYVRFVTSAPPGAARDGGEALAPHFARRVAAEVKPGAGARVR STLDAPLQRFARDTLTRALAELNAPAHRRHVQDGAVVVIDNATGEIRAWVGSSGALSAARDVDAVLAPRQAGSTLKPFLY AQALDERRLTAASLLDDAPIDLAAGGGLYIPQNYDKHFKGWVSVRTALGGSLNVPAVRTLVLVTPHRFARTLTALGLPLA EEGDYYGFSLALGSADVTLLSLANAYRALANGGVARATLDVPGGSGSGSRNGNGNDAVTSAPFAPAVSKSKVGASAVFPR AVSTKAEPAKPVPTAALSPTSASTSTAGKPAAHAAAGTRVFSEAAAYIVTDILADNNARVRTFGFDSPLATRFFSAVKTG TSKDMRDNWALGYTSRYTVGVWVGNADGSPMWDVSGVTGAAPVWAAIVGYLHRDLASRAPRPPAGVEQRRVAFERDVEPA RPEWFIAGTALDTVRLAAPATAAAGGADRPRAPLSIGAPTDGTIFAIDPDIPPKHQRIWFERAAGRAARFSWRLDGKVIG RGERLAWMPWPGSHRLELVDARGNVADAVGFEVRGAFAKTAAPPKP
Sequences:
>Translated_846_residues MFGSAFGSAFAAFGLALAPLLAAPPVRPRARRNPRPCGSPRRAALPRARTAASRTLAVAMLAAPLAAHALPAYDDVRRDW RSTDWLLLARDGTPLQRTRVELTERRGDWIALADVSPAFREAIVVSEDKRFYAHSGVDWRGIAGAAWGNLWNERTRGAST VTMQLAGLLSDTPRRSGQRSLPQKAAQAMNALRLERGWRKDQILEAYLNLVPFRGETVGLDAMSHALFGKAPSGLDVRES AVAAALVRAPNASAAKVAERACRILRDLRAAQPCESLDGYVRFVTSAPPGAARDGGEALAPHFARRVAAEVKPGAGARVR STLDAPLQRFARDTLTRALAELNAPAHRRHVQDGAVVVIDNATGEIRAWVGSSGALSAARDVDAVLAPRQAGSTLKPFLY AQALDERRLTAASLLDDAPIDLAAGGGLYIPQNYDKHFKGWVSVRTALGGSLNVPAVRTLVLVTPHRFARTLTALGLPLA EEGDYYGFSLALGSADVTLLSLANAYRALANGGVARATLDVPGGSGSGSRNGNGNDAVTSAPFAPAVSKSKVGASAVFPR AVSTKAEPAKPVPTAALSPTSASTSTAGKPAAHAAAGTRVFSEAAAYIVTDILADNNARVRTFGFDSPLATRFFSAVKTG TSKDMRDNWALGYTSRYTVGVWVGNADGSPMWDVSGVTGAAPVWAAIVGYLHRDLASRAPRPPAGVEQRRVAFERDVEPA RPEWFIAGTALDTVRLAAPATAAAGGADRPRAPLSIGAPTDGTIFAIDPDIPPKHQRIWFERAAGRAARFSWRLDGKVIG RGERLAWMPWPGSHRLELVDARGNVADAVGFEVRGAFAKTAAPPKP >Mature_846_residues MFGSAFGSAFAAFGLALAPLLAAPPVRPRARRNPRPCGSPRRAALPRARTAASRTLAVAMLAAPLAAHALPAYDDVRRDW RSTDWLLLARDGTPLQRTRVELTERRGDWIALADVSPAFREAIVVSEDKRFYAHSGVDWRGIAGAAWGNLWNERTRGAST VTMQLAGLLSDTPRRSGQRSLPQKAAQAMNALRLERGWRKDQILEAYLNLVPFRGETVGLDAMSHALFGKAPSGLDVRES AVAAALVRAPNASAAKVAERACRILRDLRAAQPCESLDGYVRFVTSAPPGAARDGGEALAPHFARRVAAEVKPGAGARVR STLDAPLQRFARDTLTRALAELNAPAHRRHVQDGAVVVIDNATGEIRAWVGSSGALSAARDVDAVLAPRQAGSTLKPFLY AQALDERRLTAASLLDDAPIDLAAGGGLYIPQNYDKHFKGWVSVRTALGGSLNVPAVRTLVLVTPHRFARTLTALGLPLA EEGDYYGFSLALGSADVTLLSLANAYRALANGGVARATLDVPGGSGSGSRNGNGNDAVTSAPFAPAVSKSKVGASAVFPR AVSTKAEPAKPVPTAALSPTSASTSTAGKPAAHAAAGTRVFSEAAAYIVTDILADNNARVRTFGFDSPLATRFFSAVKTG TSKDMRDNWALGYTSRYTVGVWVGNADGSPMWDVSGVTGAAPVWAAIVGYLHRDLASRAPRPPAGVEQRRVAFERDVEPA RPEWFIAGTALDTVRLAAPATAAAGGADRPRAPLSIGAPTDGTIFAIDPDIPPKHQRIWFERAAGRAARFSWRLDGKVIG RGERLAWMPWPGSHRLELVDARGNVADAVGFEVRGAFAKTAAPPKP
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=609, Percent_Identity=32.6765188834154, Blast_Score=202, Evalue=8e-53, Organism=Escherichia coli, GI1786343, Length=422, Percent_Identity=28.9099526066351, Blast_Score=105, Evalue=1e-23, Organism=Escherichia coli, GI87082258, Length=426, Percent_Identity=26.9953051643192, Blast_Score=86, Evalue=1e-17, Organism=Escherichia coli, GI1789601, Length=167, Percent_Identity=33.5329341317365, Blast_Score=70, Evalue=7e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 89436; Mature: 89436
Theoretical pI: Translated: 10.93; Mature: 10.93
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFGSAFGSAFAAFGLALAPLLAAPPVRPRARRNPRPCGSPRRAALPRARTAASRTLAVAM CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH LAAPLAAHALPAYDDVRRDWRSTDWLLLARDGTPLQRTRVELTERRGDWIALADVSPAFR HHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHH EAIVVSEDKRFYAHSGVDWRGIAGAAWGNLWNERTRGASTVTMQLAGLLSDTPRRSGQRS HEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHC LPQKAAQAMNALRLERGWRKDQILEAYLNLVPFRGETVGLDAMSHALFGKAPSGLDVRES HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEECHHHHHHHHHCCCCCCCCHHHH AVAAALVRAPNASAAKVAERACRILRDLRAAQPCESLDGYVRFVTSAPPGAARDGGEALA HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCCCCCCCHHHH PHFARRVAAEVKPGAGARVRSTLDAPLQRFARDTLTRALAELNAPAHRRHVQDGAVVVID HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEE NATGEIRAWVGSSGALSAARDVDAVLAPRQAGSTLKPFLYAQALDERRLTAASLLDDAPI CCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC DLAAGGGLYIPQNYDKHFKGWVSVRTALGGSLNVPAVRTLVLVTPHRFARTLTALGLPLA EEECCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCC EEGDYYGFSLALGSADVTLLSLANAYRALANGGVARATLDVPGGSGSGSRNGNGNDAVTS CCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCC APFAPAVSKSKVGASAVFPRAVSTKAEPAKPVPTAALSPTSASTSTAGKPAAHAAAGTRV CCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH FSEAAAYIVTDILADNNARVRTFGFDSPLATRFFSAVKTGTSKDMRDNWALGYTSRYTVG HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCEEEEE VWVGNADGSPMWDVSGVTGAAPVWAAIVGYLHRDLASRAPRPPAGVEQRRVAFERDVEPA EEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCC RPEWFIAGTALDTVRLAAPATAAAGGADRPRAPLSIGAPTDGTIFAIDPDIPPKHQRIWF CCCEEEEECHHHHEEECCCCHHCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCHHHHHH ERAAGRAARFSWRLDGKVIGRGERLAWMPWPGSHRLELVDARGNVADAVGFEVRGAFAKT HHHCCCCEEEEEEECCEEEECCCEEEEECCCCCCCEEEEECCCCCCHHHCHHHHCHHHHC AAPPKP CCCCCC >Mature Secondary Structure MFGSAFGSAFAAFGLALAPLLAAPPVRPRARRNPRPCGSPRRAALPRARTAASRTLAVAM CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH LAAPLAAHALPAYDDVRRDWRSTDWLLLARDGTPLQRTRVELTERRGDWIALADVSPAFR HHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHH EAIVVSEDKRFYAHSGVDWRGIAGAAWGNLWNERTRGASTVTMQLAGLLSDTPRRSGQRS HEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHC LPQKAAQAMNALRLERGWRKDQILEAYLNLVPFRGETVGLDAMSHALFGKAPSGLDVRES HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEECHHHHHHHHHCCCCCCCCHHHH AVAAALVRAPNASAAKVAERACRILRDLRAAQPCESLDGYVRFVTSAPPGAARDGGEALA HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCCCCCCCHHHH PHFARRVAAEVKPGAGARVRSTLDAPLQRFARDTLTRALAELNAPAHRRHVQDGAVVVID HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEE NATGEIRAWVGSSGALSAARDVDAVLAPRQAGSTLKPFLYAQALDERRLTAASLLDDAPI CCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC DLAAGGGLYIPQNYDKHFKGWVSVRTALGGSLNVPAVRTLVLVTPHRFARTLTALGLPLA EEECCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCC EEGDYYGFSLALGSADVTLLSLANAYRALANGGVARATLDVPGGSGSGSRNGNGNDAVTS CCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCC APFAPAVSKSKVGASAVFPRAVSTKAEPAKPVPTAALSPTSASTSTAGKPAAHAAAGTRV CCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH FSEAAAYIVTDILADNNARVRTFGFDSPLATRFFSAVKTGTSKDMRDNWALGYTSRYTVG HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCEEEEE VWVGNADGSPMWDVSGVTGAAPVWAAIVGYLHRDLASRAPRPPAGVEQRRVAFERDVEPA EEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCC RPEWFIAGTALDTVRLAAPATAAAGGADRPRAPLSIGAPTDGTIFAIDPDIPPKHQRIWF CCCEEEEECHHHHEEECCCCHHCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCHHHHHH ERAAGRAARFSWRLDGKVIGRGERLAWMPWPGSHRLELVDARGNVADAVGFEVRGAFAKT HHHCCCCEEEEEEECCEEEECCCEEEEECCCCCCCEEEEECCCCCCHHHCHHHHCHHHHC AAPPKP CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]