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The map label for this gene is ybiC [C]

Identifier: 53721363

GI number: 53721363

Start: 458196

End: 459230

Strand: Reverse

Name: ybiC [C]

Synonym: BPSS0328

Alternate gene names: 53721363

Gene position: 459230-458196 (Counterclockwise)

Preceding gene: 53721364

Following gene: 53721362

Centisome position: 14.47

GC content: 72.85

Gene sequence:

>1035_bases
ATGCATGATCGGCCAGACCTCACGCGGCCGGACGTCGTCCTGTCGCTCGACGACGTGCGCGCGCTCGCGCTGCGCGTGCT
CGCGCACCACGGGCTGTCCGACGCGCACGCGCGCGCGATCGCGAACGTGATCACGCAGGGCCAGCGCGACGAATGCCATT
CGCACGGCGTCTACCGGCTGCTCGTCTGCGCGCGCTCGCTGCGCCTCGGCAAGGTCGACCCGCAAGCGGTGCCGACGCTG
CGCCGGCTGTCGCCGTCGATCGTCGCGGTCGACGCGCATCGCGGCTTCTCGCTGCTCGCGTTCGAGACGGGCCTGCCGGT
GCTCGTCGAGATGGCGCGCCGGCACGGCATCGCCGCGATGGCGATCAACCGCTGCTACCACTTCTCGGCGCTGTGGCCGG
AGGTCGAGGCGCTCGCCGCTCACGGCCTTGCCGGCCTCGCGATGAATCCGAGCCATGGCTGGGTCGCGCCGGAAGGCGGC
ACGCGGCCGGTGTTCGGCACGAATCCGCTCGCGTTCGCGTGGCCGCGCCCGGGCGGCACGCCGTTCGTGTTCGATTTCGC
GACGAGCGCGATCGCGCGCGGCGACCTCGAACTGCACGCGAAAGCGGGCAAGCCGATTCCGCCGCACTGGGCGATCGACG
CGAACGGCGCGCCGACCACCGATCCGCAAGCCGCGCTGCAAGGTGCGATGCGCACGTTCGGCGGGCACAAGGGCTCGGCG
CTCGCGGCAATGATCGAGCTGCTCGCCGGCGCGCTGATCGGCGACATGACGAGCGCCGAGTCGCTCGCGTTCGACGAAGG
CGCCGGCGCGACGCCGTGCCATGGCGAGCTCGTGATCGCGCTCGATCCGAAGACGTTTCTCGGCGACGCACTCGACGCCG
GCCTCGCACGCGGCGAGCGCATGTTCGAGGCGATCGTCGCGCAGGGCGCGCGGCTGCCGTCGCAGCGGCGCTTCGACGCC
CGCGCGCGCAGCGCCGCGCACGACGTGCGGATCCCGGCCCGGCTCCACGACGAGATCGTCGCGCTGCTCGACTGA

Upstream 100 bases:

>100_bases
GACGTGCCCGACGCGCTGCTGCCCGATGCGCTGCGCGACGCGAACCCGCTGCGCGTGCCGCAACGCATCGACGGCGCACT
CGCGCCGCGGGAGGCGCGCG

Downstream 100 bases:

>100_bases
CGGGCGCGCCGCGCCGCCCGAAGCCGCCCGCGCGCGCCGCCGCGCGGGTGGGCGGCGCCCCCACACACGGTTTACAGTCG
GTCGGCAATTGCCGATTTCC

Product: malate/L-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MHDRPDLTRPDVVLSLDDVRALALRVLAHHGLSDAHARAIANVITQGQRDECHSHGVYRLLVCARSLRLGKVDPQAVPTL
RRLSPSIVAVDAHRGFSLLAFETGLPVLVEMARRHGIAAMAINRCYHFSALWPEVEALAAHGLAGLAMNPSHGWVAPEGG
TRPVFGTNPLAFAWPRPGGTPFVFDFATSAIARGDLELHAKAGKPIPPHWAIDANGAPTTDPQAALQGAMRTFGGHKGSA
LAAMIELLAGALIGDMTSAESLAFDEGAGATPCHGELVIALDPKTFLGDALDAGLARGERMFEAIVAQGARLPSQRRFDA
RARSAAHDVRIPARLHDEIVALLD

Sequences:

>Translated_344_residues
MHDRPDLTRPDVVLSLDDVRALALRVLAHHGLSDAHARAIANVITQGQRDECHSHGVYRLLVCARSLRLGKVDPQAVPTL
RRLSPSIVAVDAHRGFSLLAFETGLPVLVEMARRHGIAAMAINRCYHFSALWPEVEALAAHGLAGLAMNPSHGWVAPEGG
TRPVFGTNPLAFAWPRPGGTPFVFDFATSAIARGDLELHAKAGKPIPPHWAIDANGAPTTDPQAALQGAMRTFGGHKGSA
LAAMIELLAGALIGDMTSAESLAFDEGAGATPCHGELVIALDPKTFLGDALDAGLARGERMFEAIVAQGARLPSQRRFDA
RARSAAHDVRIPARLHDEIVALLD
>Mature_344_residues
MHDRPDLTRPDVVLSLDDVRALALRVLAHHGLSDAHARAIANVITQGQRDECHSHGVYRLLVCARSLRLGKVDPQAVPTL
RRLSPSIVAVDAHRGFSLLAFETGLPVLVEMARRHGIAAMAINRCYHFSALWPEVEALAAHGLAGLAMNPSHGWVAPEGG
TRPVFGTNPLAFAWPRPGGTPFVFDFATSAIARGDLELHAKAGKPIPPHWAIDANGAPTTDPQAALQGAMRTFGGHKGSA
LAAMIELLAGALIGDMTSAESLAFDEGAGATPCHGELVIALDPKTFLGDALDAGLARGERMFEAIVAQGARLPSQRRFDA
RARSAAHDVRIPARLHDEIVALLD

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=266, Percent_Identity=31.5789473684211, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786727, Length=278, Percent_Identity=30.5755395683453, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790000, Length=291, Percent_Identity=26.4604810996564, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17507179, Length=295, Percent_Identity=25.0847457627119, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536633, Length=252, Percent_Identity=26.1904761904762, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24667904, Length=261, Percent_Identity=27.9693486590038, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45553211, Length=261, Percent_Identity=27.9693486590038, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24667912, Length=261, Percent_Identity=27.9693486590038, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24667908, Length=261, Percent_Identity=27.9693486590038, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24658010, Length=295, Percent_Identity=26.7796610169492, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648360, Length=252, Percent_Identity=30.5555555555556, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 36543; Mature: 36543

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDRPDLTRPDVVLSLDDVRALALRVLAHHGLSDAHARAIANVITQGQRDECHSHGVYRL
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHCCHHHH
LVCARSLRLGKVDPQAVPTLRRLSPSIVAVDAHRGFSLLAFETGLPVLVEMARRHGIAAM
HHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCHHHH
AINRCYHFSALWPEVEALAAHGLAGLAMNPSHGWVAPEGGTRPVFGTNPLAFAWPRPGGT
HHHHHHHHHHHCHHHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCCCEEEECCCCCCC
PFVFDFATSAIARGDLELHAKAGKPIPPHWAIDANGAPTTDPQAALQGAMRTFGGHKGSA
EEEEHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHH
LAAMIELLAGALIGDMTSAESLAFDEGAGATPCHGELVIALDPKTFLGDALDAGLARGER
HHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
MFEAIVAQGARLPSQRRFDARARSAAHDVRIPARLHDEIVALLD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MHDRPDLTRPDVVLSLDDVRALALRVLAHHGLSDAHARAIANVITQGQRDECHSHGVYRL
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHCCHHHH
LVCARSLRLGKVDPQAVPTLRRLSPSIVAVDAHRGFSLLAFETGLPVLVEMARRHGIAAM
HHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCHHHH
AINRCYHFSALWPEVEALAAHGLAGLAMNPSHGWVAPEGGTRPVFGTNPLAFAWPRPGGT
HHHHHHHHHHHCHHHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCCCEEEECCCCCCC
PFVFDFATSAIARGDLELHAKAGKPIPPHWAIDANGAPTTDPQAALQGAMRTFGGHKGSA
EEEEHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHH
LAAMIELLAGALIGDMTSAESLAFDEGAGATPCHGELVIALDPKTFLGDALDAGLARGER
HHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
MFEAIVAQGARLPSQRRFDARARSAAHDVRIPARLHDEIVALLD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]