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The map label for this gene is mmr [H]

Identifier: 53721361

GI number: 53721361

Start: 454731

End: 456302

Strand: Reverse

Name: mmr [H]

Synonym: BPSS0326

Alternate gene names: 53721361

Gene position: 456302-454731 (Counterclockwise)

Preceding gene: 53721362

Following gene: 53721355

Centisome position: 14.38

GC content: 73.03

Gene sequence:

>1572_bases
ATGGACACGCATCTTCCCCACCCCGCCCTTTCCCGCGCCGCGCTCGTGCGGATCGTGTCGACCGTCAGCGCGAGCTTCGT
GATCACGCAGCTCGACGTGACGATCGTCAACGTCGCGCTCGCGCGCATCGGCATCGATCTGCATACGAGCGTCGCGGGCC
TGCAATGGATCGTCGACGCCTACACGCTCGCGCTCGCGGGCCTGATGCTGTCGGCCGGCGCGCTCGGCGACCGGTTCGGC
GCGCGCCGGCTGTTCGCCGCCGGGCTCGCGCTCTTCGCCGTCGCATCGTTCGTCTGCGGCATCGCCGCGAACGCGGCGAC
GCTCATCGCCGCGCGCGCGCTGCAAGGGCTCGCGGCGGCCGCGATGCTCCCGAACTCGCTCGCGCTGCTCAACCATGCGT
GCGCGCACGATCCACGGCTGCGGGCGCGCGCGGTCGGCTGGTGGACCGCGTCGGGCGCGATCTCGATCGCGGCGGGCCCG
GTGATCGGCGGCGTGCTGATCGCGCAGTTCGGCTGGCGCAGCATCTTCTTCGTCAATCTGCCGCTGTGCGCGGCGAGCCT
CGCCGCGACGCGTCTGTGGATCGACAGCGACGACACGCGCGCGGCAGCCGCTTCGTCGGCCTCGTCCGCTTCATCGGCCT
CGTCGGCCTCGTCCGCCTCGTCCGCCTCGTCCGCTTCATCCGCCGCCGACGGCGCGCACCATTCGCACCCGGCGGCGGAC
CGGCGCGCATCCGGCCCGAATGCCTGCGCCCCCGCGCCCAAGCGCGCCGCCGGCGCCGGAACACGCGGCCTCGACCTGCC
CGGCCAGTGCCTCGCCGTCGTCGCGCTCACGCTCTTCACCGGCGCGGTAATCGACTGGCATCCGGCGCTCGTCGCGATCG
CGCTCGCGGCGGGCGCCGCGTTCGTGTTCGTCGAATCGCGCAGCGCGCACCCGATGATGCCGCTCGCGCTGTTCAGGCGG
CGCACGTTCAGCGTCGCCGTGCTGTTCGGTGTCTGCATGAATCTGTCGTACTACGGGATCATCTTCGTGCTGAGCCTGTA
TTTGCAGCGCGTGCGCCACAACACGCCGCTCGAGGCGGGGCTCGCGTTCCTGCCGCTCACGGGGGGCTTCCTGCTGTCGA
ACGTCGCGAGCGGCTGGGCGACCGCGCACTACGGCTCGCGCCGGCCGATGATCGCCGGCGCGCTGATCGGCGCGACCGGT
TTCGCGCTGCTGAGCGCGGTGCGTGCCGATACGCCGATCGCGATGCTCGTCGTGCCGTTCCTGCTGATTCCGGGCGGCAT
GGGGCTCGCGGTGCCCGCGATGACGACGACGGTGCTCGCCTCGGTCGAACGCGCGCGCGCCGCGACCGCGTCGGCCGTGC
TCAATACCGCGCGGCAGGCGGGCGGCGCGATCGGCGTCGCCGCGTTCGGCGCGCTCGCGAGCGGCGCGCGGCCGCCGGAC
ATCGTGTCGGGATTGCACGCGTCGGCGTACGTATCGGCCGCGCTCTTCGTGTTCGCCTCGGCGATGGCGGCTTTCGTGCA
CGGCGCGCCGCAGCCGGCGGCGGGCAAGCCGGCGAACGCGAACGCACGCTGA

Upstream 100 bases:

>100_bases
GCAAGCCGCCGCCGAAAGGGCACGGCCGCCCGTGCGCGCCGCATCGACATTTCAGCAGACCCCGTAACGTCGCCGTCCCG
CGCCGCCCTACGATGCGTGC

Downstream 100 bases:

>100_bases
CGCGGCGCGAACCCGCCGCGCGCGCGTCATGTCATGAGCGAGGACGCGGGTGCGAAAGCGAAAAAACGCCCGCGGAAAAG
GGAACCATCGGGCAACGGGA

Product: transport-related membrane protein

Products: NA

Alternate protein names: MMR peptide [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MDTHLPHPALSRAALVRIVSTVSASFVITQLDVTIVNVALARIGIDLHTSVAGLQWIVDAYTLALAGLMLSAGALGDRFG
ARRLFAAGLALFAVASFVCGIAANAATLIAARALQGLAAAAMLPNSLALLNHACAHDPRLRARAVGWWTASGAISIAAGP
VIGGVLIAQFGWRSIFFVNLPLCAASLAATRLWIDSDDTRAAAASSASSASSASSASSASSASSASSAADGAHHSHPAAD
RRASGPNACAPAPKRAAGAGTRGLDLPGQCLAVVALTLFTGAVIDWHPALVAIALAAGAAFVFVESRSAHPMMPLALFRR
RTFSVAVLFGVCMNLSYYGIIFVLSLYLQRVRHNTPLEAGLAFLPLTGGFLLSNVASGWATAHYGSRRPMIAGALIGATG
FALLSAVRADTPIAMLVVPFLLIPGGMGLAVPAMTTTVLASVERARAATASAVLNTARQAGGAIGVAAFGALASGARPPD
IVSGLHASAYVSAALFVFASAMAAFVHGAPQPAAGKPANANAR

Sequences:

>Translated_523_residues
MDTHLPHPALSRAALVRIVSTVSASFVITQLDVTIVNVALARIGIDLHTSVAGLQWIVDAYTLALAGLMLSAGALGDRFG
ARRLFAAGLALFAVASFVCGIAANAATLIAARALQGLAAAAMLPNSLALLNHACAHDPRLRARAVGWWTASGAISIAAGP
VIGGVLIAQFGWRSIFFVNLPLCAASLAATRLWIDSDDTRAAAASSASSASSASSASSASSASSASSAADGAHHSHPAAD
RRASGPNACAPAPKRAAGAGTRGLDLPGQCLAVVALTLFTGAVIDWHPALVAIALAAGAAFVFVESRSAHPMMPLALFRR
RTFSVAVLFGVCMNLSYYGIIFVLSLYLQRVRHNTPLEAGLAFLPLTGGFLLSNVASGWATAHYGSRRPMIAGALIGATG
FALLSAVRADTPIAMLVVPFLLIPGGMGLAVPAMTTTVLASVERARAATASAVLNTARQAGGAIGVAAFGALASGARPPD
IVSGLHASAYVSAALFVFASAMAAFVHGAPQPAAGKPANANAR
>Mature_523_residues
MDTHLPHPALSRAALVRIVSTVSASFVITQLDVTIVNVALARIGIDLHTSVAGLQWIVDAYTLALAGLMLSAGALGDRFG
ARRLFAAGLALFAVASFVCGIAANAATLIAARALQGLAAAAMLPNSLALLNHACAHDPRLRARAVGWWTASGAISIAAGP
VIGGVLIAQFGWRSIFFVNLPLCAASLAATRLWIDSDDTRAAAASSASSASSASSASSASSASSASSAADGAHHSHPAAD
RRASGPNACAPAPKRAAGAGTRGLDLPGQCLAVVALTLFTGAVIDWHPALVAIALAAGAAFVFVESRSAHPMMPLALFRR
RTFSVAVLFGVCMNLSYYGIIFVLSLYLQRVRHNTPLEAGLAFLPLTGGFLLSNVASGWATAHYGSRRPMIAGALIGATG
FALLSAVRADTPIAMLVVPFLLIPGGMGLAVPAMTTTVLASVERARAATASAVLNTARQAGGAIGVAAFGALASGARPPD
IVSGLHASAYVSAALFVFASAMAAFVHGAPQPAAGKPANANAR

Specific function: Resistance to the epoxide antibiotic methylenomycin A; probably by mediating its efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=449, Percent_Identity=27.3942093541203, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790195, Length=169, Percent_Identity=35.5029585798817, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789042, Length=181, Percent_Identity=30.939226519337, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788710, Length=155, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790146, Length=177, Percent_Identity=31.0734463276836, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788392, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52801; Mature: 52801

Theoretical pI: Translated: 11.11; Mature: 11.11

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTHLPHPALSRAALVRIVSTVSASFVITQLDVTIVNVALARIGIDLHTSVAGLQWIVDA
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YTLALAGLMLSAGALGDRFGARRLFAAGLALFAVASFVCGIAANAATLIAARALQGLAAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLPNSLALLNHACAHDPRLRARAVGWWTASGAISIAAGPVIGGVLIAQFGWRSIFFVNL
HHCCCHHHHHHHHHCCCCCHHHEEEEEEECCCCEEEECCHHHHHHHHHHHCCCEEEEEEC
PLCAASLAATRLWIDSDDTRAAAASSASSASSASSASSASSASSASSAADGAHHSHPAAD
HHHHHHHHHHEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCC
RRASGPNACAPAPKRAAGAGTRGLDLPGQCLAVVALTLFTGAVIDWHPALVAIALAAGAA
CCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCE
FVFVESRSAHPMMPLALFRRRTFSVAVLFGVCMNLSYYGIIFVLSLYLQRVRHNTPLEAG
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHC
LAFLPLTGGFLLSNVASGWATAHYGSRRPMIAGALIGATGFALLSAVRADTPIAMLVVPF
EEEECCCCHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLIPGGMGLAVPAMTTTVLASVERARAATASAVLNTARQAGGAIGVAAFGALASGARPPD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHH
IVSGLHASAYVSAALFVFASAMAAFVHGAPQPAAGKPANANAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTHLPHPALSRAALVRIVSTVSASFVITQLDVTIVNVALARIGIDLHTSVAGLQWIVDA
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YTLALAGLMLSAGALGDRFGARRLFAAGLALFAVASFVCGIAANAATLIAARALQGLAAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLPNSLALLNHACAHDPRLRARAVGWWTASGAISIAAGPVIGGVLIAQFGWRSIFFVNL
HHCCCHHHHHHHHHCCCCCHHHEEEEEEECCCCEEEECCHHHHHHHHHHHCCCEEEEEEC
PLCAASLAATRLWIDSDDTRAAAASSASSASSASSASSASSASSASSAADGAHHSHPAAD
HHHHHHHHHHEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCC
RRASGPNACAPAPKRAAGAGTRGLDLPGQCLAVVALTLFTGAVIDWHPALVAIALAAGAA
CCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCE
FVFVESRSAHPMMPLALFRRRTFSVAVLFGVCMNLSYYGIIFVLSLYLQRVRHNTPLEAG
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHC
LAFLPLTGGFLLSNVASGWATAHYGSRRPMIAGALIGATGFALLSAVRADTPIAMLVVPF
EEEECCCCHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLIPGGMGLAVPAMTTTVLASVERARAATASAVLNTARQAGGAIGVAAFGALASGARPPD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHH
IVSGLHASAYVSAALFVFASAMAAFVHGAPQPAAGKPANANAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2828187; 12000953 [H]