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The map label for this gene is ybdL [H]

Identifier: 53720990

GI number: 53720990

Start: 4014229

End: 4015419

Strand: Reverse

Name: ybdL [H]

Synonym: BPSL3384

Alternate gene names: 53720990

Gene position: 4015419-4014229 (Counterclockwise)

Preceding gene: 53720991

Following gene: 53720989

Centisome position: 98.55

GC content: 69.61

Gene sequence:

>1191_bases
ATGGCCGCGCGCCCGTTCACGAGCCCAGGAGGATCCATGCAGAGCGCCGCCGCGCCCCGTTCGAAGCTGCCCGACGTCGG
CACGACGATCTTCACGGTCATCGGCCAGCTCGCCGCCGAGCACGAGGCGCTGAATCTGTCGCAGGGCGCGCCGAATTTCG
CGCCCGATCCGGCGCTCGTCGAGCGCGTCGCCCGCGCGATGCGAGACGGGCACAACCAGTACGCGCCGATGGCGGGCATC
GCCGCGCTGCGCGAGGCGCTCGGCGTGAAGACCGAGCGCCTGTACGGCGAGCGCTACGATCCGGACTCCGAAGTCACCAT
CGTCGCGAGCGCGAGCGAGGGGCTCTACGCGGCGATCAGCGCGCTCGTCCATCCGGGCGACGAGGTGATCTACTTCGAGC
CGTCGTTCGACAGCTACGCGCCGATCGTCCGGCTGCAGGGCGCGACGCCCGTCGCGATCAGGCTGTCGCCCGAGCGCTTT
CGCGTGAACTGGGACGAGGTGGCCGCGAAGATCACGCCGCGCACGCGGATGCTGATCGTCAACACGCCGCACAACCCGAG
CGCGACGATCCTCGGCGAGGCCGACGTCGCGCGTCTCGCGCAGCTCGTCGCGGGCACCGACATCGTGGTGCTGTCCGACG
AGGTGTACGAGCACGTCGTGTTCGACGGCGCGCGCCATCACAGCATGGCGCGCGATCGCGCGCTCGCCGAGCGCAGCGTG
ATCGTGTCGTCGTTCGGCAAGTCGTATCACGTGACGGGCTGGCGCGTCGGCTACTGCCTCGCGCCCGCCGAGCTCACGCG
CGAGCTGCGCAAGGTCCATCAGTTCATGACGTTCGCGGCCGATACGCCGATGCAGCATGCGTTCGCGGCGGCGCTCGCGG
AGCCGGCGAGCTATCTCGAGCTCGGCGCGTTCTACGAGCGCAAGCGCGACCTGCTCGTGCGCGAGCTGGCCGGCTCGCGC
TTCGAGCTGCTGCCGAGCGAGGGCTCGTTCTTCATGCTCGCGCGCTTCGGGCATTTTTCGGACGAATCGGACGCCGACTT
CGTGCTGCGTGCGATTCGCGACGCACGCGTCGCGACGATTCCGCTGTCCGCGTTCTACGCGGACGGCGCGAACACCGGCT
GCATCCGTTTGAGCTTTTCGAAGGACGACGCGACGCTCGTCGAAGGCGCGCGCCGCCTGTGCAGCCTCTGA

Upstream 100 bases:

>100_bases
CGTAAGCCATGAGTTTTTCTCATGCCTGTCATGACGAACTTTCGATTGCCGCCGGATATTGGCTCGGGCCCAATCCGCAT
CGTTGCCCCGCGCGCCGGCG

Downstream 100 bases:

>100_bases
CGCGCGCGGTGCCCGCCGCTGCGGACATGACCCGATCTCAAGGAGAAACATCGATGAAACGATTGCAATTCTGGTTCGCG
CTCGCCTGTGCATTGGGCGC

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAARPFTSPGGSMQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGI
AALREALGVKTERLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERF
RVNWDEVAAKITPRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSV
IVSSFGKSYHVTGWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSR
FELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL

Sequences:

>Translated_396_residues
MAARPFTSPGGSMQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGI
AALREALGVKTERLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERF
RVNWDEVAAKITPRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSV
IVSSFGKSYHVTGWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSR
FELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL
>Mature_395_residues
AARPFTSPGGSMQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGIA
ALREALGVKTERLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFR
VNWDEVAAKITPRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVI
VSSFGKSYHVTGWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSRF
ELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=386, Percent_Identity=32.9015544041451, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI169881279, Length=386, Percent_Identity=32.9015544041451, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI56713254, Length=411, Percent_Identity=30.1703163017032, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=30.3571428571429, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI169881281, Length=384, Percent_Identity=28.90625, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=23.6074270557029, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=52.5065963060686, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1788722, Length=337, Percent_Identity=25.8160237388724, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788627, Length=341, Percent_Identity=25.2199413489736, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=412, Percent_Identity=31.0679611650485, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71994472, Length=412, Percent_Identity=31.0679611650485, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=28.8508557457213, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17567663, Length=332, Percent_Identity=24.0963855421687, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=28.4615384615385, Blast_Score=163, Evalue=4e-41,
Organism=Drosophila melanogaster, GI28573069, Length=393, Percent_Identity=32.3155216284987, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24646114, Length=393, Percent_Identity=32.3155216284987, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI28573067, Length=393, Percent_Identity=32.3155216284987, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI28573065, Length=393, Percent_Identity=32.3155216284987, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI18859735, Length=388, Percent_Identity=24.7422680412371, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43116; Mature: 42985

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARPFTSPGGSMQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALV
CCCCCCCCCCCCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
ERVARAMRDGHNQYAPMAGIAALREALGVKTERLYGERYDPDSEVTIVASASEGLYAAIS
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEEECCCCHHHHHH
ALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKITPRTRMLIV
HHHCCCCCEEEECCCCCCCCCEEEECCCCEEEEEECHHHHCCCHHHHHHEECCCEEEEEE
NTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSV
ECCCCCCEEEECCHHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IVSSFGKSYHVTGWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLE
HHHHCCCEEEECEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
LGAFYERKRDLLVRELAGSRFELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATI
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEE
PLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL
EHHHEECCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AARPFTSPGGSMQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALV
CCCCCCCCCCCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
ERVARAMRDGHNQYAPMAGIAALREALGVKTERLYGERYDPDSEVTIVASASEGLYAAIS
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEEECCCCHHHHHH
ALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKITPRTRMLIV
HHHCCCCCEEEECCCCCCCCCEEEECCCCEEEEEECHHHHCCCHHHHHHEECCCEEEEEE
NTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSV
ECCCCCCEEEECCHHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IVSSFGKSYHVTGWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLE
HHHHCCCEEEECEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
LGAFYERKRDLLVRELAGSRFELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATI
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEE
PLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL
EHHHEECCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]