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The map label for this gene is cheA [H]

Identifier: 53720916

GI number: 53720916

Start: 3924929

End: 3927172

Strand: Reverse

Name: cheA [H]

Synonym: BPSL3306

Alternate gene names: 53720916

Gene position: 3927172-3924929 (Counterclockwise)

Preceding gene: 53720917

Following gene: 53720915

Centisome position: 96.38

GC content: 70.45

Gene sequence:

>2244_bases
ATGACTCTCGATATCACACAGTTCTACCAGACGTTCTTCGACGAAGCCGACGAGCTGCTCGCGCAGATGGAGCAGCTGCT
GCTGAACCTGGACGTCGCCTCGCCCGATCCCGAGGATCTGGCGGCGATCTTTCGCGCCGCGCACTCGATCAAGGGCGGCG
CCGCGACGTTCGGCTTCACCGCGCTCACGGAAACGACGCACATCCTCGAATCGCTGCTCGATCGCGCACGCAATCATGAG
CTCACGCTGACGAAGGAGATGGTCGATGCGTTCCTCGAGACGAAGGACGTGCTGTCCGACCAGCTTGCCGACTACCGCGC
GAGCGCCGAGCCCGATGCGGCCGCCGCGGCCGCGATCTGCGCGAAGCTCGAGCGGCTGAAGGCGTCGGCGAGCGGCGCGC
CGGCGGCGCCCGTTGCGGCGGCTGAGCCCGTGCCGGCGGCGACGGCTGCGCCGGCCACGTCCGCGATGGGCCTCTTCGGC
GCGCCCGAGCACGTCGTCGAGCAGGCGGTCGAGGCCGCGCATCCGGTGGCCGGCGCGCCCGAGGCCGCGGCCGGCGGCGA
TGGCCCGCATCTGAAGATCACGCTCACGGGCGTCGACGACAAGGATCAGGAACTGCTGACCGAGGAGCTCGGCAATCTCG
GCCGGATCGTCGGCCGCACGAAGACGGGCGACGCACTCGCGCTGTGGCTCGAGACCGACGTGTCGTCGGACGACATCGTC
GCCGTGTGCTGCTTCGTGATCGACGAAAGCCAGATCGCGATCGGCCGCGGCACCGCGCCGGGCGCGGGCGACGCGCAGGC
CGCGCCGGCGGCGCGGCAGCCGGGCGAAGCCGCGCCCGAACCCGCTGCCGAGCAAGCCGCGCCGGAACCGGCCGCGGCGC
AGCCGGCGGCGGCGCCCGTCGCCGACGCGCGCCCGGCCGCGCCGGCCGCCGCGCCGAGCGCGCCCGCACCCGCCGCGGCG
CCGGCCGCGCAAGCCGCGGCGTCCGCCGCCGCGCAGCACCAGGACGATCGCAAGCCGCGCCCGGCCGTCGCCGCGAGCGC
GGAGGGCAGCTCGATTCGCGTCGGCGTCGAGAAGGTCGACCAGTTGATCAACCTGGTCGGCGAGCTCGTGATCACGCAGG
CGATGCTCGCCGAGACGACGAGCGCGTTCGATCCGGCGCTGCACGACCGCCTGTACAACGGGATGGCGCAGCTCGAGCGC
AACGCGCGCGATCTGCAGGAAGCCGTGATGTCGATCCGGATGATGCCGATGGATTACGTGTTCAGCCGCTTTCCGCGGCT
CGTGCGCGATCTCGCGGGCAAGCTCGGCAAGCAGGTCGAGCTCGTCACGTTCGGCCAGGCGACCGAGCTCGACAAGAGCC
TCATCGAACGGATCATCGATCCGCTGACGCACCTCGTGCGCAACAGCCTCGATCACGGCATCGAGACCGTCGAGGCGCGC
CGCGCGGCGGGCAAGGACGCGGTCGGCCAGCTCGTGCTGTCGGCCGCGCACCACGGCGGCAACATCGTGATCGAGGTCAG
CGACGACGGCGCGGGCCTGAACCGCGAGCGGATCCTCGCGAAGGCGGCCAAGCAGGGGATGCAGATCTCCGAGAACATCA
GCGACGACGAAGTGTGGAACCTGATCTTCGCGCCGGGCTTCTCGACCGCCGAAGTCGTGACCGACGTGTCGGGCCGCGGC
GTCGGGATGGACGTCGTCAAGCGCAACATCCAGTCGATGGGCGGGCACGTCGAGATTTCGTCGCAGGCCGGCCGCGGCAC
GACGACGCGCATCGTGCTGCCGCTCACGCTCGCGATTCTCGACGGGATGTCGGTGAAGGTCGGCAACGAGATCTTCATCC
TGCCGCTGAACTTCGTGATGGAGTCGCTGCAGCCCGCGGCCGACGACATCTACACGATCGGCAACGGCGAGCGCGTCGTG
CGCGTGCGCGGCGAGTACCTACCGCTCGTCGCGCTGCACGAGGTGTTCTCGGTGGACGACGCGCGCACCGATCCGACGCA
GGGCATCGTCACGATCATGCAGACGGAAGGCCGCCGCTTCGCGATGCTGATCGACGAGCTGGTGGGCCAGCAGCAGGTGG
TCGTCAAGAACCTCGAGACGAACTACCGCAAGGTGTACGGCATTTCGGCCGCGACGATTCTCGGCGACGGCAGCGTCGCG
CTGATCGTCGACGTCGCGGCGCTCAATCGCGAGACCCGCGCGGCGCACGGCGCGCATTCGAGCGCCGCGCTCGCCGCGTC
CTAA

Upstream 100 bases:

>100_bases
AAGCCGATCGACCCGGACGCGCTGATCGAGCTCGTCGCGGCGCTTTCGGCGTCGTCGAGCCTCTCGTGACGAACACGACG
TTTTTAGGCGGTGAACCGGC

Downstream 100 bases:

>100_bases
CTTACGTGATCCATCGATCAGGGGGCTAACGTGTCCGAAGTCCAAACGAATCATCCGGCCGCGCCGAACGCGGCCAGCCG
CCGCGACGCCGAACAGGGCG

Product: chemotaxis two-component sensor kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 747; Mature: 746

Protein sequence:

>747_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVASPDPEDLAAIFRAAHSIKGGAATFGFTALTETTHILESLLDRARNHE
LTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAICAKLERLKASASGAPAAPVAAAEPVPAATAAPATSAMGLFG
APEHVVEQAVEAAHPVAGAPEAAAGGDGPHLKITLTGVDDKDQELLTEELGNLGRIVGRTKTGDALALWLETDVSSDDIV
AVCCFVIDESQIAIGRGTAPGAGDAQAAPAARQPGEAAPEPAAEQAAPEPAAAQPAAAPVADARPAAPAAAPSAPAPAAA
PAAQAAASAAAQHQDDRKPRPAVAASAEGSSIRVGVEKVDQLINLVGELVITQAMLAETTSAFDPALHDRLYNGMAQLER
NARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVEAR
RAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWNLIFAPGFSTAEVVTDVSGRG
VGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGNEIFILPLNFVMESLQPAADDIYTIGNGERVV
RVRGEYLPLVALHEVFSVDDARTDPTQGIVTIMQTEGRRFAMLIDELVGQQQVVVKNLETNYRKVYGISAATILGDGSVA
LIVDVAALNRETRAAHGAHSSAALAAS

Sequences:

>Translated_747_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVASPDPEDLAAIFRAAHSIKGGAATFGFTALTETTHILESLLDRARNHE
LTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAICAKLERLKASASGAPAAPVAAAEPVPAATAAPATSAMGLFG
APEHVVEQAVEAAHPVAGAPEAAAGGDGPHLKITLTGVDDKDQELLTEELGNLGRIVGRTKTGDALALWLETDVSSDDIV
AVCCFVIDESQIAIGRGTAPGAGDAQAAPAARQPGEAAPEPAAEQAAPEPAAAQPAAAPVADARPAAPAAAPSAPAPAAA
PAAQAAASAAAQHQDDRKPRPAVAASAEGSSIRVGVEKVDQLINLVGELVITQAMLAETTSAFDPALHDRLYNGMAQLER
NARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVEAR
RAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWNLIFAPGFSTAEVVTDVSGRG
VGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGNEIFILPLNFVMESLQPAADDIYTIGNGERVV
RVRGEYLPLVALHEVFSVDDARTDPTQGIVTIMQTEGRRFAMLIDELVGQQQVVVKNLETNYRKVYGISAATILGDGSVA
LIVDVAALNRETRAAHGAHSSAALAAS
>Mature_746_residues
TLDITQFYQTFFDEADELLAQMEQLLLNLDVASPDPEDLAAIFRAAHSIKGGAATFGFTALTETTHILESLLDRARNHEL
TLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAICAKLERLKASASGAPAAPVAAAEPVPAATAAPATSAMGLFGA
PEHVVEQAVEAAHPVAGAPEAAAGGDGPHLKITLTGVDDKDQELLTEELGNLGRIVGRTKTGDALALWLETDVSSDDIVA
VCCFVIDESQIAIGRGTAPGAGDAQAAPAARQPGEAAPEPAAEQAAPEPAAAQPAAAPVADARPAAPAAAPSAPAPAAAP
AAQAAASAAAQHQDDRKPRPAVAASAEGSSIRVGVEKVDQLINLVGELVITQAMLAETTSAFDPALHDRLYNGMAQLERN
ARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVEARR
AAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWNLIFAPGFSTAEVVTDVSGRGV
GMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGNEIFILPLNFVMESLQPAADDIYTIGNGERVVR
VRGEYLPLVALHEVFSVDDARTDPTQGIVTIMQTEGRRFAMLIDELVGQQQVVVKNLETNYRKVYGISAATILGDGSVAL
IVDVAALNRETRAAHGAHSSAALAAS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=741, Percent_Identity=55.8704453441296, Blast_Score=762, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78193; Mature: 78062

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVASPDPEDLAAIFRAAHSIKGGAATFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ALTETTHILESLLDRARNHELTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AKLERLKASASGAPAAPVAAAEPVPAATAAPATSAMGLFGAPEHVVEQAVEAAHPVAGAP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCC
EAAAGGDGPHLKITLTGVDDKDQELLTEELGNLGRIVGRTKTGDALALWLETDVSSDDIV
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHH
AVCCFVIDESQIAIGRGTAPGAGDAQAAPAARQPGEAAPEPAAEQAAPEPAAAQPAAAPV
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
ADARPAAPAAAPSAPAPAAAPAAQAAASAAAQHQDDRKPRPAVAASAEGSSIRVGVEKVD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEECHHHHH
QLINLVGELVITQAMLAETTSAFDPALHDRLYNGMAQLERNARDLQEAVMSIRMMPMDYV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVEAR
HHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWN
HHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHHCCCCCHHHEE
LIFAPGFSTAEVVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAIL
EEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEHHHHHHHHH
DGMSVKVGNEIFILPLNFVMESLQPAADDIYTIGNGERVVRVRGEYLPLVALHEVFSVDD
CCCEEEECCEEEEEEHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCCC
ARTDPTQGIVTIMQTEGRRFAMLIDELVGQQQVVVKNLETNYRKVYGISAATILGDGSVA
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCHHHEECCEEEEEECCCCEE
LIVDVAALNRETRAAHGAHSSAALAAS
EEEEHHHHCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TLDITQFYQTFFDEADELLAQMEQLLLNLDVASPDPEDLAAIFRAAHSIKGGAATFGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ALTETTHILESLLDRARNHELTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AKLERLKASASGAPAAPVAAAEPVPAATAAPATSAMGLFGAPEHVVEQAVEAAHPVAGAP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCC
EAAAGGDGPHLKITLTGVDDKDQELLTEELGNLGRIVGRTKTGDALALWLETDVSSDDIV
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHH
AVCCFVIDESQIAIGRGTAPGAGDAQAAPAARQPGEAAPEPAAEQAAPEPAAAQPAAAPV
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
ADARPAAPAAAPSAPAPAAAPAAQAAASAAAQHQDDRKPRPAVAASAEGSSIRVGVEKVD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEECHHHHH
QLINLVGELVITQAMLAETTSAFDPALHDRLYNGMAQLERNARDLQEAVMSIRMMPMDYV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVEAR
HHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQISENISDDEVWN
HHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCHHCCCCCHHHEE
LIFAPGFSTAEVVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAIL
EEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEHHHHHHHHH
DGMSVKVGNEIFILPLNFVMESLQPAADDIYTIGNGERVVRVRGEYLPLVALHEVFSVDD
CCCEEEECCEEEEEEHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCCC
ARTDPTQGIVTIMQTEGRRFAMLIDELVGQQQVVVKNLETNYRKVYGISAATILGDGSVA
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCHHHEECCEEEEEECCCCEE
LIVDVAALNRETRAAHGAHSSAALAAS
EEEEHHHHCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]