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The map label for this gene is recQ [H]

Identifier: 53720827

GI number: 53720827

Start: 3814140

End: 3816074

Strand: Reverse

Name: recQ [H]

Synonym: BPSL3219

Alternate gene names: 53720827

Gene position: 3816074-3814140 (Counterclockwise)

Preceding gene: 53720828

Following gene: 53720826

Centisome position: 93.66

GC content: 67.65

Gene sequence:

>1935_bases
GTGCGACCTTCGTCCACCTTTCGCGGCGGCGACGTTGGTAAAATTCACGCCACCGCCCCTTTTCGCAGCCCATCCATCTC
CAGATCCATGTCCCGTTCGCTCGAAATTCTCAACGAAGTCTTCGGCTATCCCGCCTTCCGAGGTCAACAGGGCGAGATCG
TCGAGCACGTTGCGGCGGGCGGCGACTGTCTCGTGCTGATGCCCACGGGCGGCGGCAAGTCGCTCTGCTACCAGATTCCG
GCGCTCGTGCGCAGCGAAGCGGGCCGCGGCGCGGGCATCGTCGTGTCGCCGCTCATCGCGCTGATGCAGGATCAGGTCGC
CGCATTGTCCGAGGTCGGCGTGCGCGCCGCGTATCTGAACTCGACGCTGTCGGGGGCCGAGGCGGCCGCGACCGAACGCG
CGCTGCGCGACGGCGACATCGATCTGCTCTACGTCGCGCCCGAGCGGCTGATGACGCCGCGCTTCCTCGATCTGCTCGAG
CGCGCGCGCATCGGGCTTTTCGCGATCGACGAGGCGCACTGCGTATCGCAGTGGGGGCACGATTTCCGGCCCGAGTACAT
TCAGTTGTCGGTGCTGCACGAGCGCTTTCCGGACGTGCCGCGGATCGCGCTGACCGCGACCGCCGATGCGATCACCCGCG
ACGAGATCGTGCAGCGTCTGGCGCTCGACGACGCGCGAATCTTCGTGTCGAGCTTCGACCGGCCGAACATCCGCTACCGG
ATCGTCGAAAAGGACAACGCGCGCTCGCAGTTGCTCGACTTCATTCGCGCCGAGCATACGAACGCCGACGGTACGACCGA
CGCCGGCGTCGTGTACTGCCTGTCGCGCCGCAAGGTCGAGGAGACGGCCGAATGGCTGAAGGCGCAAGGGGTTCGTGCGC
TGCCGTATCACGCGGGAATGGAGTTCGAGATCCGGCAGAAGCACCAGGAGATGTTCCAGCGCGAGGAAGGGGTCGTGATG
TGCGCGACGATCGCATTCGGCATGGGCATCGACAAGCCGGACGTGCGCTTCGTCGCACACCTGGATCTGCCGAAGAGCGT
CGAAGGCTATTACCAGGAGACCGGACGCGCGGGGCGCGACGGCCTGCCGGCGAACGCGTGGATGGCGTACGGGCTCGGCG
ACGTCGTTCAGCAGCGCAAGATGATCGACGAATCGGAAGCCGACGACACGCACAAGCGTGTCCAGACGTCGAAGCTCGAC
GCGCTGCTCGGGCTGTGCGAGACGGCATCGTGCCGCCGCGTGCGGCTCCTCGCGTATTTCGGCGAGACGAGCGGCCCGTG
CGGCAACTGCGACACCTGCCTCGAGCCGCCGGCGACATGGGACGCGACGCGCGAAGCGCAGATGGCGCTGTCGTGCGTAT
TCCGCGCGCAGCGCGCAAGCGGCTTCAATTTCGGCGCGAGCCATCTGATCGAAGTGCTGCGCGGTGCGCGGACCGAGAAG
GTCCAGCAACGCGGCCACGACAGTCTCAGCACGTTCGGCATCGGCGCCGAGTTGTCCGAAGCCGAATGGCGCGCGATCTT
CCGGCAGCTCGTCGCGTTCGGCTATCTCGCCGTCGACCACGGCGGCTTCGGCGCGCTCGTGCTGACGGAGGCGAGCAAGC
CGGTGCTCAAGGGCGAGGAGAAGGTCACGCTGCGCCGCTACGTGAAGCCGGCGCGCACACGGCAGTCCTCCGGCCGCAGC
GGCGCGCGCGTCGATCCGACGGCCGGCATGAGCGCGCGCGAGCGCGCGTGCTGGGAGCGCCTGCGCGCGTGGCGCGCGGA
AACGGCGAAGAGCGACGGCGTGCCTGCGTACGTGATCTTCCACGACGCGACGCTCGCGGAGATCGCGCGCAACGCGCCCG
AATCGATCGACGATCTGCGCCATATCCCCGGAATCGGCGCGCGCAAGCTCGATCGCTTCGGCGACGAGATTCTCGAGGTC
GTCGAATCGGCCTGA

Upstream 100 bases:

>100_bases
AGCCGCCTTGCCTTGCCGGCCGATGGAGCCGCCCGGTTTCGACCGGGCGGCTTTTTTTATGCGTGCGCGGCGTGGGCCGC
GCGTCGGCCGAATGGACGAC

Downstream 100 bases:

>100_bases
GCAGGCCGCCCGCCTTCGCATTCCGGCACCAAAAATCACGCAAGCTGTTGACTCGCTTGGGATTTTCGGAATATCATGCC
GGGTTCCGGTTCTCGGTGGG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MRPSSTFRGGDVGKIHATAPFRSPSISRSMSRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIP
ALVRSEAGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLE
RARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVM
CATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLD
ALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEK
VQQRGHDSLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRS
GARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEV
VESA

Sequences:

>Translated_644_residues
MRPSSTFRGGDVGKIHATAPFRSPSISRSMSRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIP
ALVRSEAGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLE
RARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVM
CATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLD
ALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEK
VQQRGHDSLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRS
GARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEV
VESA
>Mature_644_residues
MRPSSTFRGGDVGKIHATAPFRSPSISRSMSRSLEILNEVFGYPAFRGQQGEIVEHVAAGGDCLVLMPTGGGKSLCYQIP
ALVRSEAGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLNSTLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLE
RARIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGMEFEIRQKHQEMFQREEGVVM
CATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLD
ALLGLCETASCRRVRLLAYFGETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEK
VQQRGHDSLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEEKVTLRRYVKPARTRQSSGRS
GARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIFHDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEV
VESA

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=650, Percent_Identity=34.4615384615385, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI14591902, Length=416, Percent_Identity=37.5, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI14591904, Length=416, Percent_Identity=37.5, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI148612816, Length=447, Percent_Identity=39.1498881431767, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI169218196, Length=606, Percent_Identity=32.1782178217822, Blast_Score=260, Evalue=4e-69,
Organism=Homo sapiens, GI110735439, Length=606, Percent_Identity=32.1782178217822, Blast_Score=258, Evalue=9e-69,
Organism=Homo sapiens, GI51242947, Length=415, Percent_Identity=39.5180722891566, Blast_Score=252, Evalue=1e-66,
Organism=Homo sapiens, GI51242943, Length=415, Percent_Identity=39.5180722891566, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI284005309, Length=347, Percent_Identity=36.5994236311239, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI148613856, Length=347, Percent_Identity=25.6484149855908, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI38201710, Length=347, Percent_Identity=25.6484149855908, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI4758138, Length=346, Percent_Identity=25.1445086705202, Blast_Score=71, Evalue=4e-12,
Organism=Escherichia coli, GI48994977, Length=614, Percent_Identity=44.7882736156352, Blast_Score=532, Evalue=1e-152,
Organism=Escherichia coli, GI87082221, Length=346, Percent_Identity=24.2774566473988, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=663, Percent_Identity=35.1432880844646, Blast_Score=340, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI71987997, Length=410, Percent_Identity=40, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI71987993, Length=410, Percent_Identity=40, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI32564293, Length=698, Percent_Identity=29.7994269340974, Blast_Score=285, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17552866, Length=448, Percent_Identity=36.6071428571429, Blast_Score=255, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17510309, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510307, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995514, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995718, Length=336, Percent_Identity=23.5119047619048, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71987143, Length=331, Percent_Identity=25.6797583081571, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=350, Percent_Identity=24, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=542, Percent_Identity=35.4243542435424, Blast_Score=350, Evalue=4e-97,
Organism=Saccharomyces cerevisiae, GI6325138, Length=335, Percent_Identity=25.0746268656716, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324778, Length=232, Percent_Identity=27.1551724137931, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646066, Length=642, Percent_Identity=36.4485981308411, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=456, Percent_Identity=37.0614035087719, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24664230, Length=437, Percent_Identity=37.7574370709382, Blast_Score=265, Evalue=7e-71,
Organism=Drosophila melanogaster, GI62472181, Length=437, Percent_Identity=37.7574370709382, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI21358123, Length=370, Percent_Identity=34.3243243243243, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI28574962, Length=354, Percent_Identity=24.8587570621469, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 70914; Mature: 70914

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSSTFRGGDVGKIHATAPFRSPSISRSMSRSLEILNEVFGYPAFRGQQGEIVEHVAAG
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
GDCLVLMPTGGGKSLCYQIPALVRSEAGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLN
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLERARIGLFAIDEAHCVSQWGH
HHCCCHHHHHHHHHHCCCCEEEEEECHHHHCCHHHHHHHHHHCCCEEEECHHHHHHHCCC
DFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
CCCCCCEEEHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGM
EEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
EFEIRQKHQEMFQREEGVVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRD
CHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCC
GLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLDALLGLCETASCRRVRLLAYF
CCCCHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHH
VQQRGHDSLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEE
HHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCH
KVTLRRYVKPARTRQSSGRSGARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIF
HHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
HDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEVVESA
ECCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPSSTFRGGDVGKIHATAPFRSPSISRSMSRSLEILNEVFGYPAFRGQQGEIVEHVAAG
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
GDCLVLMPTGGGKSLCYQIPALVRSEAGRGAGIVVSPLIALMQDQVAALSEVGVRAAYLN
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLSGAEAAATERALRDGDIDLLYVAPERLMTPRFLDLLERARIGLFAIDEAHCVSQWGH
HHCCCHHHHHHHHHHCCCCEEEEEECHHHHCCHHHHHHHHHHCCCEEEECHHHHHHHCCC
DFRPEYIQLSVLHERFPDVPRIALTATADAITRDEIVQRLALDDARIFVSSFDRPNIRYR
CCCCCCEEEHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IVEKDNARSQLLDFIRAEHTNADGTTDAGVVYCLSRRKVEETAEWLKAQGVRALPYHAGM
EEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
EFEIRQKHQEMFQREEGVVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRD
CHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCC
GLPANAWMAYGLGDVVQQRKMIDESEADDTHKRVQTSKLDALLGLCETASCRRVRLLAYF
CCCCHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GETSGPCGNCDTCLEPPATWDATREAQMALSCVFRAQRASGFNFGASHLIEVLRGARTEK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHH
VQQRGHDSLSTFGIGAELSEAEWRAIFRQLVAFGYLAVDHGGFGALVLTEASKPVLKGEE
HHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCH
KVTLRRYVKPARTRQSSGRSGARVDPTAGMSARERACWERLRAWRAETAKSDGVPAYVIF
HHHHHHHHCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
HDATLAEIARNAPESIDDLRHIPGIGARKLDRFGDEILEVVESA
ECCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]