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The map label for this gene is mraW [H]

Identifier: 53720643

GI number: 53720643

Start: 3615182

End: 3616123

Strand: Reverse

Name: mraW [H]

Synonym: BPSL3033

Alternate gene names: 53720643

Gene position: 3616123-3615182 (Counterclockwise)

Preceding gene: 53720644

Following gene: 53720642

Centisome position: 88.75

GC content: 65.61

Gene sequence:

>942_bases
ATGGGAAACGAATTCCAGCATCGCACGGTGCTGTTGGATGAAGCGGTCGATGCGCTCGTGACGCGGCCCGACGGCGTGTA
TGTCGACGGCACGTTCGGGCGCGGCGGCCATAGCCGCGCGGTGCTCGCGCGCCTGGGCTACGCGGGACGGCTGATCGCGT
TCGACAAGGATCCGCGCGCGATCGAGACGGCCGAGAGCATCGAGGATGCGCGGTTCGAGATCGTCCATGACAGTTTCGCG
GCGATGAAGGGCGCACTCGATGCGCGCGGAATAGGGCGGGTGTCGGGCGTGCTGCTGGATCTGGGCGTGTCTTCGCCGCA
GGTGGACGATCCGGCGCGCGGCTTCAGCTTCCGCGCGAACGGTCCGCTCGACATGCGGATGGACCCGACGCGTGGCGAAT
CGGCGGCCGAGTGGCTCGCACGGGCGTCGGTGCAGGAATTGACGGAGGTGATACGAGATTATGGGGAAGAACGGTTTGCT
TTTCAGATTGCAAAGGCGATTGTTGCTCGCCGGGCAGAGTCCGACCGTCTCGGGCCTCTCGACAGCACGGGCGAGCTTGC
CCAAATCGTGGGTCACGTCGTCAAGACCCGTGAGAAGGGTAAGGATCCGGCAACCCGCACCTTTCAGGCTATACGGATTC
ACGTCAATCAAGAGCTTGCGGACCTGCAAGTCGTTCTAGAGGCAGCACTGTCGTTGTTGGAGCAAGGGGGCCGGCTGGTG
GTCATCAGCTTTCATTCGCTCGAGGACCGGATCGTCAAGCGATTCCTGCAGGCGCACGCAAGCGCGCCTGCGGTCGACCG
CCGCCTGCCGATTCGCGCGGCCGACCTGCCCCGCCCGCCGCTCAAGCTGCTCGGCCGGATGTTCCCGAACGACGCGGAAG
TCGCGGCCAATCCGCGTGCCCGTTCGGCGGTGATGCGCATCGCGGAGCGCGTCGCGCCATGA

Upstream 100 bases:

>100_bases
CGCAGACCTACACCGCGAAGGAGCAGGCGGCGATGGCGCAGGGCATGCCCGAAGCGCTGAAGAATTTCACGTTCTGATTG
CGGTGAGGAAGACGCCCGCG

Downstream 100 bases:

>100_bases
GCCGCCTCAATATCTTCCTGCTGATCATCGTGATGGGATGCGCGCTGTCGGTCGTCAATTCGACGAACCAGCAGCGGCAG
ATCTTCATCCAGTTGCAGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGYAGRLIAFDKDPRAIETAESIEDARFEIVHDSFA
AMKGALDARGIGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP

Sequences:

>Translated_313_residues
MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGYAGRLIAFDKDPRAIETAESIEDARFEIVHDSFA
AMKGALDARGIGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP
>Mature_312_residues
GNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGYAGRLIAFDKDPRAIETAESIEDARFEIVHDSFAA
MKGALDARGIGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAF
QIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLVV
ISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=37.5739644970414, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI165377202, Length=198, Percent_Identity=37.8787878787879, Blast_Score=115, Evalue=5e-26,
Organism=Escherichia coli, GI1786270, Length=315, Percent_Identity=53.968253968254, Blast_Score=335, Evalue=2e-93,
Organism=Drosophila melanogaster, GI62472493, Length=331, Percent_Identity=36.5558912386707, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28571637, Length=331, Percent_Identity=36.5558912386707, Blast_Score=168, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34209; Mature: 34078

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGYAGRLIAFDKDPRA
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCH
IETAESIEDARFEIVHDSFAAMKGALDARGIGRVSGVLLDLGVSSPQVDDPARGFSFRAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCEEECC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
RSAVMRIAERVAP
HHHHHHHHHHHCC
>Mature Secondary Structure 
GNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGYAGRLIAFDKDPRA
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCH
IETAESIEDARFEIVHDSFAAMKGALDARGIGRVSGVLLDLGVSSPQVDDPARGFSFRAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCEEECC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
RSAVMRIAERVAP
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA