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The map label for this gene is kdgR [H]

Identifier: 53720580

GI number: 53720580

Start: 3544753

End: 3545670

Strand: Reverse

Name: kdgR [H]

Synonym: BPSL2972

Alternate gene names: 53720580

Gene position: 3545670-3544753 (Counterclockwise)

Preceding gene: 53720581

Following gene: 53720579

Centisome position: 87.02

GC content: 70.37

Gene sequence:

>918_bases
ATGAACAAAACGCCCATGACGCTCGCCTTGAACGGCGCGACCGCTGACCGCCCCGACACGCCGGGCATGCCCGACGCGAC
GCTCGCCGACAGCATCGGCGCGACCAGCACGCCGCTCGATCTCGCCGCGCAGCAGGCGGGCACGCAAACGCTGCTGCGCG
GGCTCGCGATTCTCGAGGCGGTCGCGGGCGGCGCGCGCGACATGCGCGCGATCGGCGCCGCGCTCGGCACGACGCGCAGC
ACGACGCACCGTCTCGTCAGCAGCCTCGTGCAGGCGCGCTATCTGCGCCAGGTGCAAGGCGGCTATCTGCTCGGCCCGAA
GCTGATCGAGCTTGGCACGATCGCGCTCGAGCAGATGCCGCTCACGGCGGTCGCGCGCCCGCATCTCGAGGCGCTCGCGC
AAGCGACGCTCGACACGATCCACCTCGGCGTGCGCGACGGCGACGACGTGCTCTACATCGACAAGATTCCCGGCACGCGC
GGCCTGGAGATGCGCTCGCGGATCGGTCACCGGATGCCGCTCGCGTCGACGGGGATCGGCAAGGCGATGATGCTCGACCT
CGATCCCGACACGTGGCGCTCGCTGTTCGACGCGTCCAAGCGCGCGCTCGCGGGGGTGAACTTCAAGCCGGATCGCCGGC
CCGACGTCGGCACGTTCCTGCAGCGAATGGCGCACTATGCGGCGGGCGGCTACACGTTCGATCTCGAGGAAAACGAAACG
TCGATTCGCTGCGTCGCCGCGCCGGTGCGCGATGCGTCGGGCGCGATCGTCGCCGCGCTGTCGGTCGCAAGCACGATTCC
GTACATGTCGCTCGACCGGATGAACGAGCTCGTGCCGCTCGTGCAGCGCGGCGCGCGCGCGATTTCGGCCGATCTCGGCT
GGAGCGCGCCGCAGGCGACGCGCAGGATCAAGCGATGA

Upstream 100 bases:

>100_bases
CGCCCCCCTACAATCCGAAGCACATCGAAACGCTTCGGCAGATGTGCGGCCGCCGGAAATCTCCGGCGCGCGCGTCTGGT
TCGCCGGAGTTCATCGCACC

Downstream 100 bases:

>100_bases
CGGCGCAAGCGAGCACGCCCGCGCTCATCGGGCTCGACTGGGGCACGACGTCGCTGCGCGCGTACCTGTTCGCCGCCGAC
GGCTCGGTGCTCGACACGCG

Product: IclR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNKTPMTLALNGATADRPDTPGMPDATLADSIGATSTPLDLAAQQAGTQTLLRGLAILEAVAGGARDMRAIGAALGTTRS
TTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTR
GLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRSLFDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENET
SIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMNELVPLVQRGARAISADLGWSAPQATRRIKR

Sequences:

>Translated_305_residues
MNKTPMTLALNGATADRPDTPGMPDATLADSIGATSTPLDLAAQQAGTQTLLRGLAILEAVAGGARDMRAIGAALGTTRS
TTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTR
GLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRSLFDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENET
SIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMNELVPLVQRGARAISADLGWSAPQATRRIKR
>Mature_305_residues
MNKTPMTLALNGATADRPDTPGMPDATLADSIGATSTPLDLAAQQAGTQTLLRGLAILEAVAGGARDMRAIGAALGTTRS
TTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTR
GLEMRSRIGHRMPLASTGIGKAMMLDLDPDTWRSLFDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENET
SIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMNELVPLVQRGARAISADLGWSAPQATRRIKR

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=262, Percent_Identity=33.206106870229, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789999, Length=259, Percent_Identity=32.4324324324324, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786468, Length=252, Percent_Identity=30.1587301587302, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786715, Length=256, Percent_Identity=28.515625, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788581, Length=249, Percent_Identity=29.718875502008, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790752, Length=256, Percent_Identity=25, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 32535; Mature: 32535

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTPMTLALNGATADRPDTPGMPDATLADSIGATSTPLDLAAQQAGTQTLLRGLAILEA
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAGGARDMRAIGAALGTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMP
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCC
LTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRIGHRMPLASTGIG
HHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCC
KAMMLDLDPDTWRSLFDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENET
CEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
SIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMNELVPLVQRGARAISADLGWSAPQAT
EEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RRIKR
HHHCC
>Mature Secondary Structure
MNKTPMTLALNGATADRPDTPGMPDATLADSIGATSTPLDLAAQQAGTQTLLRGLAILEA
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAGGARDMRAIGAALGTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMP
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCC
LTAVARPHLEALAQATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRIGHRMPLASTGIG
HHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCC
KAMMLDLDPDTWRSLFDASKRALAGVNFKPDRRPDVGTFLQRMAHYAAGGYTFDLEENET
CEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
SIRCVAAPVRDASGAIVAALSVASTIPYMSLDRMNELVPLVQRGARAISADLGWSAPQAT
EEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RRIKR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]