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The map label for this gene is ubiA [H]

Identifier: 53720469

GI number: 53720469

Start: 3422301

End: 3423251

Strand: Reverse

Name: ubiA [H]

Synonym: BPSL2861

Alternate gene names: 53720469

Gene position: 3423251-3422301 (Counterclockwise)

Preceding gene: 53720470

Following gene: 53720465

Centisome position: 84.02

GC content: 66.04

Gene sequence:

>951_bases
ATGGCGCGGCCCGGCGTTTTGCCGCGAATCCCGCGCGGTTCTACAATGCCGGGGTTACGATCGAGGGCTCGCCGCCCGTT
CTCGCCGATGCTCGCCCGTTTTCCCCTCTATTTGCGGCTGATCCGGATGGACAAGCCGATCGGCAGCCTGCTGCTGCTCT
GGCCGACGCTCAATGCGCTGTGGATCGCGTCCGACGGCCATCCTGCGCCGTCGCTCGTCGTGATCTTCGCGCTCGGCACG
CTGCTGATGCGCTCGGCCGGCTGCGCGATCAACGATTACGCCGATCGCGATTTCGACCGCCACGTGAAGCGCACCGCCGA
GCGGCCGCTCACGTCGGGCAAGATCCGCGCATGGGAGGCGATCGCGATCGCGGTCGGCCTCGCGCTCGTGTCGTTTCTGC
TGATCCTGCCGCTCAACGGGCTGACGAAGGAGCTGTCCGTCGTCGCGGTGTTCGTCGCGGCGACCTACCCGTTCATGAAG
CGCTTCTTCGCGATTCCGCAGGCGTATCTCGGCATCGCGTTCGGCTTCGGGATTCCGATGGCGTTCGCGGCCGTGCAGGA
TACGGTGCCGATGATCGCTTGGGCGATGCTCGCGGCCAACGTGTTCTGGTCGGTTGCGTACGACACCGCGTATGCGATGG
TCGATCGCGACGACGATCTGAAGATCGGCATGCGCACGTCGGCGATCACGTTCGGCCGCCATGACGTGCTCGCGATCATG
CTCTGCTACGCGGCGATGCTCGGCATCTACGTGTGGCTCGGCGCGGCGCTGCATTTCGGTTGGCCGTATTGGGCGGGCTG
GGCGGCGGCGGCCGGCTGCTCGATCTACCATTACACGCTGATCAAGGATCGCGAGCGGATGGCGTGCTTCGCCGCGTTCA
GGCACAACAACTGGTTGGGCGGCGTGCTTTTCGCGGGGATCGCCGCGCATTACGCGCTCGCCGTGCGGTAA

Upstream 100 bases:

>100_bases
CGCGGCGGCGCCGCACGCGCCTCGGCTGCCTGCCCGTTTCGCGCCCGGCCGTCGGGCAGGGCGGCCGCCCGAACGCAAGC
GGAAACGACAAAAAAGGGCG

Downstream 100 bases:

>100_bases
GCGGCGAGCCGGCGGGCGCGGTGCGCTCGGGCGCGATCGGGAAGCGGCCTGCGGGCCGCTTTCTTTTTGGGGCGATGCTT
TGGGGGGCGAGGCGGGCGTG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MARPGVLPRIPRGSTMPGLRSRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFALGT
LLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMK
RFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIM
LCYAAMLGIYVWLGAALHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR

Sequences:

>Translated_316_residues
MARPGVLPRIPRGSTMPGLRSRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFALGT
LLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMK
RFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIM
LCYAAMLGIYVWLGAALHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR
>Mature_315_residues
ARPGVLPRIPRGSTMPGLRSRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNALWIASDGHPAPSLVVIFALGTL
LMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEAIAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKR
FFAIPQAYLGIAFGFGIPMAFAAVQDTVPMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIML
CYAAMLGIYVWLGAALHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLGGVLFAGIAAHYALAVR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=313, Percent_Identity=32.2683706070287, Blast_Score=151, Evalue=6e-37,
Organism=Escherichia coli, GI1790473, Length=273, Percent_Identity=53.1135531135531, Blast_Score=278, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17553718, Length=281, Percent_Identity=33.8078291814947, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI32565247, Length=280, Percent_Identity=32.1428571428571, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17553720, Length=337, Percent_Identity=28.7833827893175, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=40.8759124087591, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=40.6015037593985, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324370, Length=309, Percent_Identity=28.1553398058252, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355567, Length=299, Percent_Identity=32.1070234113712, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 34889; Mature: 34758

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPGVLPRIPRGSTMPGLRSRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNAL
CCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEHCCCCCEE
WIASDGHPAPSLVVIFALGTLLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEA
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCHHHHH
IAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAAVQDTVPMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCEEECCHHHHHHHH
LCYAAMLGIYVWLGAALHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCCCCHH
GVLFAGIAAHYALAVR
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARPGVLPRIPRGSTMPGLRSRARRPFSPMLARFPLYLRLIRMDKPIGSLLLLWPTLNAL
CCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEHCCCCCEE
WIASDGHPAPSLVVIFALGTLLMRSAGCAINDYADRDFDRHVKRTAERPLTSGKIRAWEA
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCHHHHH
IAIAVGLALVSFLLILPLNGLTKELSVVAVFVAATYPFMKRFFAIPQAYLGIAFGFGIPM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAAVQDTVPMIAWAMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCEEECCHHHHHHHH
LCYAAMLGIYVWLGAALHFGWPYWAGWAAAAGCSIYHYTLIKDRERMACFAAFRHNNWLG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCCCCHH
GVLFAGIAAHYALAVR
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA