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The map label for this gene is pyrR [H]

Identifier: 53720301

GI number: 53720301

Start: 3218726

End: 3219244

Strand: Reverse

Name: pyrR [H]

Synonym: BPSL2691

Alternate gene names: 53720301

Gene position: 3219244-3218726 (Counterclockwise)

Preceding gene: 53720302

Following gene: 53720300

Centisome position: 79.01

GC content: 73.6

Gene sequence:

>519_bases
ATGAGTTCAATTGACGCCGAGGCGCTTTACCGCGTCCTGCTTGACCAGATTCGCGCGGCCTATGGCGACGCCGCGTTCGC
GCAAGCCGGCGGCCCCGTGCTCGCGGGCATCCACAGCGGCGGCGCGTGGCTCGCCGAGCGCCTCGCGCGCGACCTCGGCG
CGCCGGGCTTCGGCGTCGTCAACGTCGCGCTGCACCGCGACGATTACGCGAAGAAGGGGCTGCACAGCCAGGCGAGCCCG
ACGTCGCTGCCGTTCGAAGTCGAAGGGCGGCGCATCGTGCTCGTCGACGACGTACTGTACACCGGGCGCACGGTGCGCGC
GGCGCTCAACGAGCTATACGACTACGGGCGGCCCGCGGCCGTCGAACTCGCGGTGCTCGCCGATCGCGGCGGGCGCGAGC
TGCCGGTCGCGGCGCGCTTCGTCGGCGGCGCGCTCGCCGTCGACGCGGACGCGACGCTCGTGCTCGAGCGCGCGGACGCG
GGACGCTTCACGCTTCGCACCGAGGCGCGCGCGGGCTGA

Upstream 100 bases:

>100_bases
CGCGCGGGCCTGCGCGCGCGCGGCGACGCGGCGGATCGCGTCGATGCGGAAGCCGCCCGCGTCATCCTTCAACAATACCT
CGACGGACTGCCCGATCATC

Downstream 100 bases:

>100_bases
ACGCGCGCGACGCATTCCGGCCGCCCGTGCGCGTCGCGCATCCGGGCGCCGTTTGGCAACACGTTGGAATCACGCACATC
ATGACGACCGACACCTCCGG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSSIDAEALYRVLLDQIRAAYGDAAFAQAGGPVLAGIHSGGAWLAERLARDLGAPGFGVVNVALHRDDYAKKGLHSQASP
TSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAAVELAVLADRGGRELPVAARFVGGALAVDADATLVLERADA
GRFTLRTEARAG

Sequences:

>Translated_172_residues
MSSIDAEALYRVLLDQIRAAYGDAAFAQAGGPVLAGIHSGGAWLAERLARDLGAPGFGVVNVALHRDDYAKKGLHSQASP
TSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAAVELAVLADRGGRELPVAARFVGGALAVDADATLVLERADA
GRFTLRTEARAG
>Mature_171_residues
SSIDAEALYRVLLDQIRAAYGDAAFAQAGGPVLAGIHSGGAWLAERLARDLGAPGFGVVNVALHRDDYAKKGLHSQASPT
SLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAAVELAVLADRGGRELPVAARFVGGALAVDADATLVLERADAG
RFTLRTEARAG

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 18130; Mature: 17998

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIDAEALYRVLLDQIRAAYGDAAFAQAGGPVLAGIHSGGAWLAERLARDLGAPGFGVV
CCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEE
NVALHRDDYAKKGLHSQASPTSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAA
EEEEECCHHHHHCCCCCCCCCCCCEEECCCEEEEECCCHHCCHHHHHHHHHHHHCCCCCC
VELAVLADRGGRELPVAARFVGGALAVDADATLVLERADAGRFTLRTEARAG
EEEEEEECCCCCCCCHHHHHHCCEEEECCCCEEEEEECCCCCEEEECCCCCC
>Mature Secondary Structure 
SSIDAEALYRVLLDQIRAAYGDAAFAQAGGPVLAGIHSGGAWLAERLARDLGAPGFGVV
CCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEE
NVALHRDDYAKKGLHSQASPTSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAA
EEEEECCHHHHHCCCCCCCCCCCCEEECCCEEEEECCCHHCCHHHHHHHHHHHHCCCCCC
VELAVLADRGGRELPVAARFVGGALAVDADATLVLERADAGRFTLRTEARAG
EEEEEEECCCCCCCCHHHHHHCCEEEECCCCEEEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]