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The map label for this gene is nhaA [H]

Identifier: 53720054

GI number: 53720054

Start: 2951945

End: 2952946

Strand: Reverse

Name: nhaA [H]

Synonym: BPSL2448

Alternate gene names: 53720054

Gene position: 2952946-2951945 (Counterclockwise)

Preceding gene: 53720055

Following gene: 53720051

Centisome position: 72.47

GC content: 68.16

Gene sequence:

>1002_bases
ATGTCCGATCAAATCAATCCGCCCGATTCGTCTTCGTCCCCCGCTGCGAACGCCGCCCCCCGAGAACCGAGTTGGGAGCG
CGCCGTGCTCGAGCGCGTCGCGCTCGCGGCGATCAAGGAGCAGCGCGCCGCGCGGCGCTGGAGGATCTTCTTTCGCTTCG
CGTTCCTCGCCGTGCTCGGCGCGCTCGCGTTCGCGTTCCTCAGCGTGTCCGGCGACGGCGGCAAGCTCGCGAGCGGCCGC
CACACGGCGGTCGTGACGATCGACGGCGAGATCGCCGCGAGCACCAACGCGAACGCCGAGGACATCAACACGGCGCTCGA
CAGCGCGTTCGAGGATTCGGGCACGGTCGGCGTCGTGCTGAAGATCAACAGCCCGGGCGGCAGCCCGGTGCAGGCGGGCA
TCGTCTACGACGAGATCCGGCGGCTGCGCAAGAAGTATCCGGCGAAGCCGCTTTACGTCGTCGTCTCCGACATGTGCGCG
TCGGGCGGCTACTACATCGCGGCGGCGGCGGACAAGATCTACGTCGACAAGGCGAGCATCGTCGGCTCGATCGGCGTGCT
GATGGACGGGTTCGGCTTCACCGGCCTGATGGGCAAGCTGGGCGTCGAGCGGCGCCTGCATACGTCGGGCGAGAACAAGG
GCTTCTTCGATCCGTTCTCGCCGGAGACGCCGAAGATGGATGCGCACGCGCAGGAAATGCTCGACGAGATCCACGCGCAG
TTCATCAAGGCGGTGAAGGACGGCCGCGGCGCGCGCCTGCACGAATCGCCGGACATTTTCTCCGGGCTTTTCTGGACGGG
TGCGAAGAGCATCGAGCTCGGCCTCGCCGACGATTACGGGACGACCGATACCGTCGCGCGCGACGTGCTGAAGGCGCCCG
ACCTCGTCGACTACACGGTCAAGGAAAGCCTGACCGATCGCGTCGCGCGCCGCTTCGGCGCGGCGCTCGGCAAGGCCGCG
CTGAAGGCGGCCGTCGCCGGCGGCGAGCTGAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGTCCGGGTCGACGAGCGCGACACGCCCGACGGCCGCGCGGTGTTCTGGCTGCCCGACGGCGATTTGCGGCCGGCCCCTT
CTGACCACTGACTTTCACGC

Downstream 100 bases:

>100_bases
AGGCGCGGGCCGCTTCGCGCGGCTCGCGCCGGTTCGCGTCAGCTCGCGAGCAGCAGGAAGATCGCGGGGCGCTTGTGCAG
ATCGGGCACGGGCGCCTTTT

Product: peptidase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSDQINPPDSSSSPAANAAPREPSWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGGKLASGR
HTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCA
SGGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAA
LKAAVAGGELKLR

Sequences:

>Translated_333_residues
MSDQINPPDSSSSPAANAAPREPSWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGGKLASGR
HTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCA
SGGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAA
LKAAVAGGELKLR
>Mature_332_residues
SDQINPPDSSSSPAANAAPREPSWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLGALAFAFLSVSGDGGKLASGRH
TAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVLKINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCAS
GGYYIAAAADKIYVDKASIVGSIGVLMDGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQF
IKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDTVARDVLKAPDLVDYTVKESLTDRVARRFGAALGKAAL
KAAVAGGELKLR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=221, Percent_Identity=33.4841628959276, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 35485; Mature: 35353

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQINPPDSSSSPAANAAPREPSWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAFAFLSVSGDGGKLASGRHTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVL
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
KINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCASGGYYIAAAADKIYVDKASI
EEECCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCEEEEEECCEEEEEHHHH
VGSIGVLMDGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDTVARDVLKAPDLVDYTV
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHH
KESLTDRVARRFGAALGKAALKAAVAGGELKLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure 
SDQINPPDSSSSPAANAAPREPSWERAVLERVALAAIKEQRAARRWRIFFRFAFLAVLG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAFAFLSVSGDGGKLASGRHTAVVTIDGEIAASTNANAEDINTALDSAFEDSGTVGVVL
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
KINSPGGSPVQAGIVYDEIRRLRKKYPAKPLYVVVSDMCASGGYYIAAAADKIYVDKASI
EEECCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCEEEEEECCEEEEEHHHH
VGSIGVLMDGFGFTGLMGKLGVERRLHTSGENKGFFDPFSPETPKMDAHAQEMLDEIHAQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FIKAVKDGRGARLHESPDIFSGLFWTGAKSIELGLADDYGTTDTVARDVLKAPDLVDYTV
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHH
KESLTDRVARRFGAALGKAALKAAVAGGELKLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA