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The map label for this gene is degP [H]

Identifier: 53720039

GI number: 53720039

Start: 2939113

End: 2940570

Strand: Reverse

Name: degP [H]

Synonym: BPSL2433

Alternate gene names: 53720039

Gene position: 2940570-2939113 (Counterclockwise)

Preceding gene: 53720040

Following gene: 53720038

Centisome position: 72.17

GC content: 69.41

Gene sequence:

>1458_bases
TTGACGCCGCTTGCCGCGCAATCGGCGACGGCGGCTCCGAATGTCACGACCACGCCCGCCGCAACGGGCGCCGTGCCCGC
GGCGCGCGCGGGCCTGCCCGATTTCGCGGACCTCGTCGAGCGGGTCGGCCCGGCGGTCGTCAACATCCGGACGACGGCGA
ACGTGCCGGCCGATACGCGCGGCGCGCTGCCGCCCGGCCTCGACAACGGCGACATGTCGGAATTCTTCCGCCGCTTCTTC
GGCATTCCGTTGCCGCAGGGGCCGGGCGGGCAGAAGAACGCGCCGAGCACGCCCGATGCGCCCGACACCGAACAGAACCG
CGGCGTGGGCTCGGGCTTCATCCTGTCGCCGGACGGCTATGTGATGACGAACGCGCACGTCGTCGACGACGCGGACACGA
TCTACGTGACGCTCACCGACAAGCGCGAATTCAAGGCAAAGCTCATCGGCGTCGACGAGCGCACGGACGTCGCGATCGTG
AAGATCAACGCGTCGAGCCTGCCGACCGTCGCGATCGGCGATTCGAACCGCGTGCGCGTCGGCGAATGGGTCGTCGCGAT
CGGTTCGCCGTTCGGCCTCGACAACACCGTCACGGCCGGCATCGTCAGCGCAAAGGGCCGCAACACCGGCGACTATCTGC
CGTTCATCCAGACGGACGTCGCGGTCAACCCCGGCAACTCGGGCGGCCCGCTCATCAACATGCAGGGCGAGGTGATCGGC
ATCAACTCGCAGATCTACAGCCGCACGGGCGGCTTCATGGGCATTTCGTTCGCGATTCCGATCGACGAGGCGATGCGCGT
CGCCGAGCAGCTGAAGGCATCGGGCAAGGTCACGCGCGGCCGGATCGCGGTCGCGATCGGCGAGGTGACGAAGGAAGTGG
CGGATTCGATCGGCCTGCCGAAGGCCGAAGGCGCGCTCGTCAGCAGCGTCGAGCCAGGCGGCCCGGCCGACAAGGCGGGC
CTGCAGCCGGGTGACATCATCCTGAAGTTCAACGGCCGTCCGGTGGAGGCGGCGTCGGATCTGCCGCGCATGGTCGGCGA
CACGAAGCCGGGCGCGAAGGCGACGGTGACGGTGTGGCGCAAGGGGCAATCGCGCGATCTGCCGATCACGATCGCGGAAT
TCCCGGCCGACAAGGCCGCGAAGGCCGACAGCCGTCAGGCGCCGCAGCAGAAGCCGCGCAGCAGCGCGCTCGGCCTGACG
GTCAGCGACCTGTCGCCCGAGCAGTTGAAGACGCTCAAGCTGCGCAACGGCGTGCAGATCGACGCGGTCGACGGCCCGGC
CTCGCGCGCGGGGCTGCAGCGCGGCGACATCGTGCTGCGCGTCGGCGACGTCGACATCACGAGCGCGAAGCAGTTCGTCG
ACGTGACGTCGAAGCTCGATCCGCAGCGCGCGGTCGCGGTGCTCGTGCGGCGCGGCGAGAACACGCAGTTCATCCCGATC
CGGCCGCGTCAGAAGTGA

Upstream 100 bases:

>100_bases
GCGTCTGCCATAGAATACAAGGCTTCCAAGTAACCCTTCGGTTTCCGACATGATGAATCCCTCGCTGCGCACCTGGCTCG
TCGCCGCGGCGGTGACGGCC

Downstream 100 bases:

>100_bases
GCGCCGCCGCGCGTTTCACGCTGTACGGCCGCGGCTGGTGCCATTTGTGCGACGAGATGCGAGACGCGCTCGCGCCCGTG
GCGGCCGAATGCTCGGCGAG

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTPLAAQSATAAPNVTTTPAATGAVPAARAGLPDFADLVERVGPAVVNIRTTANVPADTRGALPPGLDNGDMSEFFRRFF
GIPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERTDVAIV
KINASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVNPGNSGGPLINMQGEVIG
INSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLPKAEGALVSSVEPGGPADKAG
LQPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKADSRQAPQQKPRSSALGLT
VSDLSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQRAVAVLVRRGENTQFIPI
RPRQK

Sequences:

>Translated_485_residues
MTPLAAQSATAAPNVTTTPAATGAVPAARAGLPDFADLVERVGPAVVNIRTTANVPADTRGALPPGLDNGDMSEFFRRFF
GIPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERTDVAIV
KINASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVNPGNSGGPLINMQGEVIG
INSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLPKAEGALVSSVEPGGPADKAG
LQPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKADSRQAPQQKPRSSALGLT
VSDLSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQRAVAVLVRRGENTQFIPI
RPRQK
>Mature_484_residues
TPLAAQSATAAPNVTTTPAATGAVPAARAGLPDFADLVERVGPAVVNIRTTANVPADTRGALPPGLDNGDMSEFFRRFFG
IPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERTDVAIVK
INASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVNPGNSGGPLINMQGEVIGI
NSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLPKAEGALVSSVEPGGPADKAGL
QPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKADSRQAPQQKPRSSALGLTV
SDLSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQRAVAVLVRRGENTQFIPIR
PRQK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=355, Percent_Identity=34.6478873239437, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI22129776, Length=356, Percent_Identity=33.7078651685393, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=36, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=39.8406374501992, Blast_Score=146, Evalue=5e-35,
Organism=Escherichia coli, GI1789629, Length=488, Percent_Identity=34.8360655737705, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1786356, Length=490, Percent_Identity=33.6734693877551, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789630, Length=277, Percent_Identity=39.7111913357401, Blast_Score=193, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=37.4045801526718, Blast_Score=159, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 50683; Mature: 50552

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLAAQSATAAPNVTTTPAATGAVPAARAGLPDFADLVERVGPAVVNIRTTANVPADTR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCEEEEEEEECCCCCCCC
GALPPGLDNGDMSEFFRRFFGIPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGY
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEECCCCE
VMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERTDVAIVKINASSLPTVAIGDSNRVRV
EEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCEEE
GEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVNPGNSGGPLINMQGEVIG
CEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCCCCEEEECCCEEE
INSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLP
ECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCEECCEEEEEHHHHHHHHHHHCCCC
KAEGALVSSVEPGGPADKAGLQPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWR
CCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEEE
KGQSRDLPITIAEFPADKAAKADSRQAPQQKPRSSALGLTVSDLSPEQLKTLKLRNGVQI
CCCCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCHHCEEEEECCCHHHHHHHHHCCCCEE
DAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQRAVAVLVRRGENTQFIPI
EECCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHEECCCCCEEEEC
RPRQK
CCCCC
>Mature Secondary Structure 
TPLAAQSATAAPNVTTTPAATGAVPAARAGLPDFADLVERVGPAVVNIRTTANVPADTR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCEEEEEEEECCCCCCCC
GALPPGLDNGDMSEFFRRFFGIPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGY
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEECCCCE
VMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERTDVAIVKINASSLPTVAIGDSNRVRV
EEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCEEE
GEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVNPGNSGGPLINMQGEVIG
CEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCCCCEEEECCCEEE
INSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLP
ECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCEECCEEEEEHHHHHHHHHHHCCCC
KAEGALVSSVEPGGPADKAGLQPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWR
CCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEEE
KGQSRDLPITIAEFPADKAAKADSRQAPQQKPRSSALGLTVSDLSPEQLKTLKLRNGVQI
CCCCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCHHCEEEEECCCHHHHHHHHHCCCCEE
DAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQRAVAVLVRRGENTQFIPI
EECCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHEECCCCCEEEEC
RPRQK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]