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The map label for this gene is hscB

Identifier: 53719896

GI number: 53719896

Start: 2754661

End: 2755188

Strand: Reverse

Name: hscB

Synonym: BPSL2286

Alternate gene names: 53719896

Gene position: 2755188-2754661 (Counterclockwise)

Preceding gene: 53719897

Following gene: 53719895

Centisome position: 67.62

GC content: 67.99

Gene sequence:

>528_bases
ATGGTTTCGTTGAAGGACAGCCACTTCGATCTCTTTCATTTGCCGGCGCGATTCGCGCTCGACGAGCCGACGCTCGACGC
CGCGTACCGCGCCGTGCAGTCGCAGGTGCACCCGGATCGCTTCGCCGCCGCGGGCGACGCGCAAAAGCGCATCGCCATGC
AATGGGCGACGCGCGCGAACGAGGCATATCAGACGCTGCGCGATCCGCTCAAGCGGGCGACGTACCTGCTGCACCTGCGC
GGCGTCGATGTCGGCGCGGAGAACAACACGGCGATGGAGCCGGCGTTCCTGATGCAGCAGATGGAGTGGCGCGAGCGCAT
CGAGGATGCGGCGGGCGCGAAGAACGTCGACGCGCTCGACGCGCTTCTCGCCGAATTGCGCGACGAGCGGCGCGCGCGCC
TCGCGAAGCTGGGTGCGCTGCTCGACAGCGGCTCGGACCAGGGCGCGGCCGAGGCCGTGCGCCAACTGATGTTCGTCGAG
CGCGTATCGGCCGAGATCGGCGCTCAGATCGAGCGTCTCGAACACTAA

Upstream 100 bases:

>100_bases
CGGGGCGGGCAAGAGGCGGCGCGGGCCGCCTTTTTAATGGGCGGCACTTCGGTCGACGTGCCGCGGTCGACAACGAGTTG
AGCGCGAGAGCGACTACGCG

Downstream 100 bases:

>100_bases
CCGCGCGCTTTACGCACGCGATGCAAGCGGGGCTTCGGCCCTCATCGAACACACGAGATGGCTTTACTGCAAATTTCCGA
ACCCGGCATGGCGCCCGCGC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLR
GVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVE
RVSAEIGAQIERLEH

Sequences:

>Translated_175_residues
MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLR
GVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVE
RVSAEIGAQIERLEH
>Mature_175_residues
MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLR
GVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVE
RVSAEIGAQIERLEH

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=164, Percent_Identity=26.219512195122, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788876, Length=157, Percent_Identity=36.9426751592357, Blast_Score=110, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17541320, Length=144, Percent_Identity=26.3888888888889, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161084223, Length=168, Percent_Identity=31.547619047619, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_BURMA (Q62IZ4)

Other databases:

- EMBL:   CP000010
- RefSeq:   YP_103325.1
- ProteinModelPortal:   Q62IZ4
- SMR:   Q62IZ4
- GeneID:   3088438
- GenomeReviews:   CP000010_GR
- KEGG:   bma:BMA1705
- TIGR:   BMA1705
- HOGENOM:   HBG751004
- OMA:   AQRVAMQ
- PhylomeDB:   Q62IZ4
- ProtClustDB:   PRK03578
- BioCyc:   BMAL243160:BMA_1705-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- PANTHER:   PTHR11821
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 19583; Mature: 19583

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRAN
CCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
EAYQTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRAN
CCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
EAYQTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA