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The map label for this gene is abgR [H]

Identifier: 53719682

GI number: 53719682

Start: 2475308

End: 2476240

Strand: Reverse

Name: abgR [H]

Synonym: BPSL2069

Alternate gene names: 53719682

Gene position: 2476240-2475308 (Counterclockwise)

Preceding gene: 53719683

Following gene: 53719681

Centisome position: 60.77

GC content: 66.88

Gene sequence:

>933_bases
ATGAAAGTATCGCTGCGTCATTTACGTGCGTTCGTGGCGGTGGCTCGGGAAGGCAGCTTCACGGCCGCCGCGGGCGCGCT
GTGCCTCACGCAGTCGACGCTGACGAAGACGATCCGCGAGTTCGAACAGGCGCTCGGCGTGCACGTGTTCGAGCGCAATA
CGCGGCGCATCGCGCTCACGCCGTACGGCGCGGCGTTCCTCGTCGACGCGGTGAGAATCCTGAACGACCTCGATCTCGCG
CTCGACGGCGTCAACCAGCAACTCCTCGGAAACAGCGGCACCGTACGCGTCGCAAGCGGCCTCGCGTTCGCGTCGACGGT
CATGCCGTGCGTGATCCGGGCCTTGCACGCGCAGGAGCCCGGCATTCACGTGGACTTGCTCGACGACACGAGTGGCGGCG
TGATCCGGCGGATCGAATCCGGCGAGGTCGACGTGGGGATCGGCTCGTACGTCGGCATGGCCGGCAACGCGCTGAGCGTG
AGGCGCATCCTGAGCGCGCGTCTGGGCGTGCTGTTTCCGGTCGGCTATCCGAAGATTCCGTCGCGGCCCACGCTCGCCAG
CCTGAACGAGATTCCGATCCTGCGCGACTCGGACGAGTCGAGCATCGCCGCCGCGTTCCGGCAGCAGGCGCCCGATCTCT
GGGAGCGGATGAGGCGAAAGGTGTCCGTCACGAATCTCGATTTGCAGCTCGCGCTGGTTCGCGAGGGCATCGGCGCGTGC
ATCGTGTCGGCATTGGCGGCGTCGCATCCGTCCGCGCGGGGGATGCCGTATCGCCTGCTCGTCGAGCCGGAAATGACGCG
GGACGTCTATGTGTTCACTCGCCGCGACGTGTCGCTGCTGCCGGCCGCCGCGCGGTTCGTCGACATTCTGATGAACGTGC
TTCCGTCGATCGATTTCGCCGAGGGCGTCGTACTCGCTTGCGACGGCGCGTGA

Upstream 100 bases:

>100_bases
ATGGCCGGTTGGACGTTTGGCGGTGCAATGAGCGCGGTGTCGCAAAGGCGGGCTCATGGCCGCTGAATGGATGGGCTGCG
ACCGGTTTCGCGCAAATTCG

Downstream 100 bases:

>100_bases
ACGCCACGCGCCGCGAGCGTGCGGCGCGACAGCCCTTGCCGGCCTTTGTCGAACCACCGCGCGTGCGTCGAAGCGCGGCG
AACCGCCGTGCGCCGCGTTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALTPYGAAFLVDAVRILNDLDLA
LDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDVGIGSYVGMAGNALSV
RRILSARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTNLDLQLALVREGIGAC
IVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFAEGVVLACDGA

Sequences:

>Translated_310_residues
MKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALTPYGAAFLVDAVRILNDLDLA
LDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDVGIGSYVGMAGNALSV
RRILSARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTNLDLQLALVREGIGAC
IVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFAEGVVLACDGA
>Mature_310_residues
MKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALTPYGAAFLVDAVRILNDLDLA
LDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEPGIHVDLLDDTSGGVIRRIESGEVDVGIGSYVGMAGNALSV
RRILSARLGVLFPVGYPKIPSRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTNLDLQLALVREGIGAC
IVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFAEGVVLACDGA

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=183, Percent_Identity=28.9617486338798, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693105, Length=299, Percent_Identity=26.7558528428094, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081904, Length=147, Percent_Identity=34.6938775510204, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI157672245, Length=296, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=165, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788887, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787879, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082132, Length=178, Percent_Identity=32.5842696629214, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=122, Percent_Identity=33.6065573770492, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788296, Length=195, Percent_Identity=27.1794871794872, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=131, Percent_Identity=28.2442748091603, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788626, Length=162, Percent_Identity=29.6296296296296, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33344; Mature: 33344

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALT
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEC
PYGAAFLVDAVRILNDLDLALDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEP
CCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCC
GIHVDLLDDTSGGVIRRIESGEVDVGIGSYVGMAGNALSVRRILSARLGVLFPVGYPKIP
CCEEEEEECCCCCEEEEECCCCEEECCCHHHCCCCCHHHHHHHHHHHHCEEEECCCCCCC
SRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTNLDLQLALVREGIGAC
CCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
IVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFA
HHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGVVLACDGA
CCEEEEECCC
>Mature Secondary Structure
MKVSLRHLRAFVAVAREGSFTAAAGALCLTQSTLTKTIREFEQALGVHVFERNTRRIALT
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEC
PYGAAFLVDAVRILNDLDLALDGVNQQLLGNSGTVRVASGLAFASTVMPCVIRALHAQEP
CCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCC
GIHVDLLDDTSGGVIRRIESGEVDVGIGSYVGMAGNALSVRRILSARLGVLFPVGYPKIP
CCEEEEEECCCCCEEEEECCCCEEECCCHHHCCCCCHHHHHHHHHHHHCEEEECCCCCCC
SRPTLASLNEIPILRDSDESSIAAAFRQQAPDLWERMRRKVSVTNLDLQLALVREGIGAC
CCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
IVSALAASHPSARGMPYRLLVEPEMTRDVYVFTRRDVSLLPAAARFVDILMNVLPSIDFA
HHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGVVLACDGA
CCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]