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The map label for this gene is phoP [H]

Identifier: 53719678

GI number: 53719678

Start: 2471650

End: 2472360

Strand: Reverse

Name: phoP [H]

Synonym: BPSL2065

Alternate gene names: 53719678

Gene position: 2472360-2471650 (Counterclockwise)

Preceding gene: 53719679

Following gene: 53719677

Centisome position: 60.68

GC content: 64.56

Gene sequence:

>711_bases
TTGTCGAGACAAAAAGTGGTGCTTATTTACCTGATCGAGGACGACGAGGTCCAGGCGCGGTGTTACGCGGCCATCCTGCA
GCATGCCGGTTACAGCGTGCGCGTCCTGCCGGACGGCGAGCGCGCGTTGCGCGAGATACAGCGCGCGGCGCCCGACCTGA
TCGTGCTGGACCGGCGCCTGCCGGACATCGACGGCCTGGAGATCATCGCGTGGGTGCGCGAGCGCTGCGCGCCGCTGCCG
ATACTCGTGCTGACCAACGCGGTGCTCGAGACCGATCTCGTCGAAGCGCTCGAGGCGGGCGCCGACGACTATCTGATCAA
GCCGCCACGAGAACGGGAATTCGTCGCCCGCGTCAATGCGCTTCGCCGCCGCGCGAGCATCAGCAAGCAATTCGAAGGCA
CGATCGAAATCGGCGGCTACCGGATCGCGACCGTCGAGCGCGCCGTCTATCTCGCGGGCGAGCGCATTCCGTTGTCGCCG
AAGGAGTACGAGATCGTCGAGTTGCTCGCGCGGCACGTCGGGCAGGTCGTGCCGCGCAAGACCATCATCAGCCGCGTCTG
GGGGCGCGCGGCCGAGGAGGAAGTTTCCCGTTCGCTCGATACTCACATCTACCGCATCCGCAGGAAGATGAATCTGTCGC
GCCGCAATGGCGCGATGCTTCGCGTCATCTATACGCATGGATTCCGGCTGGACGATTTTAGCCATGTGTGA

Upstream 100 bases:

>100_bases
AGTCCTTCGGATTCCTGGCTGTTCAAGCAGTGCACGATTCCGGCTTGCCCGTTCCTCGAGGTTCGGGGGGCGGTTCGTCG
GGCTGCTGCGTGGTCGCTGG

Downstream 100 bases:

>100_bases
TTGCTTATTCGAGATAGCGGCGCGCGTGAGACAAGTGCCGTTTCTAATTGGATGACGATATTTTTGAGATATTGAATGTG
CGGCGCGCGGCGATGGCGAG

Product: putative two component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSRQKVVLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGLEIIAWVRERCAPLP
ILVLTNAVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSP
KEYEIVELLARHVGQVVPRKTIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV

Sequences:

>Translated_236_residues
MSRQKVVLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGLEIIAWVRERCAPLP
ILVLTNAVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSP
KEYEIVELLARHVGQVVPRKTIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV
>Mature_235_residues
SRQKVVLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGLEIIAWVRERCAPLPI
LVLTNAVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPK
EYEIVELLARHVGQVVPRKTIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=206, Percent_Identity=33.0097087378641, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=31.0810810810811, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=33.0357142857143, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082012, Length=203, Percent_Identity=33.0049261083744, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790860, Length=204, Percent_Identity=33.8235294117647, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=28.5067873303167, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=30.3571428571429, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786911, Length=202, Percent_Identity=31.1881188118812, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=204, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=215, Percent_Identity=31.6279069767442, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787229, Length=214, Percent_Identity=34.5794392523364, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI145693140, Length=212, Percent_Identity=31.6037735849057, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=25.3275109170306, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790437, Length=100, Percent_Identity=32, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=100, Percent_Identity=31, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27033; Mature: 26902

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQKVVLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRL
CCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEECCCC
PDIDGLEIIAWVRERCAPLPILVLTNAVLETDLVEALEAGADDYLIKPPREREFVARVNA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHH
LRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPKEYEIVELLARHVGQVVPRK
HHHHHHHHHHCCCEEEECCEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
TIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEECCCCCCC
>Mature Secondary Structure 
SRQKVVLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRL
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEECCCC
PDIDGLEIIAWVRERCAPLPILVLTNAVLETDLVEALEAGADDYLIKPPREREFVARVNA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHH
LRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPKEYEIVELLARHVGQVVPRK
HHHHHHHHHHCCCEEEECCEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
TIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]