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The map label for this gene is hisC [H]

Identifier: 53719338

GI number: 53719338

Start: 2030608

End: 2031618

Strand: Reverse

Name: hisC [H]

Synonym: BPSL1724

Alternate gene names: 53719338

Gene position: 2031618-2030608 (Counterclockwise)

Preceding gene: 53719339

Following gene: 53719337

Centisome position: 49.86

GC content: 64.49

Gene sequence:

>1011_bases
GTGAGCGTTGGCGAGGCAATGGATACCGAAGTGCGGGCGGCGGCGCAAGCCGTCTGCCTGGCGTTCAATGAAAACCCGGA
AGCGGTGGAGCCGCGCGTGCAGGCCGCGATTGCTGCCGCGGCCGCGCGGATCAATCGCTACCCGTTTGACGCCGAACCGC
GCGTCATGCGCAAGCTCGCCGAGCATTTCAGCTGTCCCGAGGACAACCTGATGCTGGTGCGCGGCATCGACGAATGCTTC
GATCGAATCAGCGCCGAATTTTCGTCGATGCGCTTCGTTACCGCATGGCCGGGCTTCGACGGCTATCGCGCACGCATCGC
CGTCAGCGGGCTGAGACACTTCGAAATCGGCCTGACCGACGATCTGCTGCTCGATCCGAACGATCTCGCCCAAGTCTCGC
GTGACGATTGCGTCGTGCTCGCCAATCCTTCGAATCCGACCGGCCAGGCGCTGAGCGCGGGCGAGCTCGATCAATTGAGG
CAGCGCGCGGGCAAGTTGCTGATCGACGAAACCTACGTCGATTATTCGTCGTTTCGCGCCCGCGGCCTGGCTTACGGCGA
GAACGAACTGGTGTTTCGTTCGTTCTCGAAATCCTACGGCCTCGCCGGCTTGCGGCTCGGCGCGCTGTTCGGGCCGAGCG
AGCTGATTGCCGCGATGAAGCGCAAGCAGTGGTTCTGCAACGTCGGCACGCTCGATCTGCATGCGCTCGAAGCCGCGCTC
GACAACGATCGCGCACGTGAGGCGCACATCGCGAAGACGCTCGCGCAGCGCCGCCGCGTCGCCGACGCGCTGCGCGGGCT
CGGCTACCGCGTCGCGTCGTCCGAGGCCAATTTCGTGCTCGTCGAAAACGCCGCCGGCGAGCGCACGCTGCGGTTCCTGC
GCGAACGGGGCATTCAGGTGAAGGACGCCGGCCAGTTCGGACTTCACCACCACATCAGAATCAGCATCGGCCGTGAAGAG
GACAACGATCGGTTGCTCGCGGCGCTGGCCGAATATTCCGACCACTCATAA

Upstream 100 bases:

>100_bases
GAAAACGAGCGGGCCGGCCTGAATCCGCCCCCGCGCTAAAGCCCGTGCGCACGATGCATCGGGCAGGAATCGACAAATCA
GAATCGGCAAGGATGAAATC

Downstream 100 bases:

>100_bases
GGTGACTCCATGACCGCTGCAACGTCCGTGCGTGCGCAAGCGCGCGAAGAAGACCTGTCTGTCAAAGAAATCCTGGATTC
GCGCTGGTTTCAGCCCGAGA

Product: putative histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSVGEAMDTEVRAAAQAVCLAFNENPEAVEPRVQAAIAAAAARINRYPFDAEPRVMRKLAEHFSCPEDNLMLVRGIDECF
DRISAEFSSMRFVTAWPGFDGYRARIAVSGLRHFEIGLTDDLLLDPNDLAQVSRDDCVVLANPSNPTGQALSAGELDQLR
QRAGKLLIDETYVDYSSFRARGLAYGENELVFRSFSKSYGLAGLRLGALFGPSELIAAMKRKQWFCNVGTLDLHALEAAL
DNDRAREAHIAKTLAQRRRVADALRGLGYRVASSEANFVLVENAAGERTLRFLRERGIQVKDAGQFGLHHHIRISIGREE
DNDRLLAALAEYSDHS

Sequences:

>Translated_336_residues
MSVGEAMDTEVRAAAQAVCLAFNENPEAVEPRVQAAIAAAAARINRYPFDAEPRVMRKLAEHFSCPEDNLMLVRGIDECF
DRISAEFSSMRFVTAWPGFDGYRARIAVSGLRHFEIGLTDDLLLDPNDLAQVSRDDCVVLANPSNPTGQALSAGELDQLR
QRAGKLLIDETYVDYSSFRARGLAYGENELVFRSFSKSYGLAGLRLGALFGPSELIAAMKRKQWFCNVGTLDLHALEAAL
DNDRAREAHIAKTLAQRRRVADALRGLGYRVASSEANFVLVENAAGERTLRFLRERGIQVKDAGQFGLHHHIRISIGREE
DNDRLLAALAEYSDHS
>Mature_335_residues
SVGEAMDTEVRAAAQAVCLAFNENPEAVEPRVQAAIAAAAARINRYPFDAEPRVMRKLAEHFSCPEDNLMLVRGIDECFD
RISAEFSSMRFVTAWPGFDGYRARIAVSGLRHFEIGLTDDLLLDPNDLAQVSRDDCVVLANPSNPTGQALSAGELDQLRQ
RAGKLLIDETYVDYSSFRARGLAYGENELVFRSFSKSYGLAGLRLGALFGPSELIAAMKRKQWFCNVGTLDLHALEAALD
NDRAREAHIAKTLAQRRRVADALRGLGYRVASSEANFVLVENAAGERTLRFLRERGIQVKDAGQFGLHHHIRISIGREED
NDRLLAALAEYSDHS

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=327, Percent_Identity=24.7706422018349, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322075, Length=356, Percent_Identity=23.314606741573, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 37184; Mature: 37053

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGEAMDTEVRAAAQAVCLAFNENPEAVEPRVQAAIAAAAARINRYPFDAEPRVMRKLA
CCCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
EHFSCPEDNLMLVRGIDECFDRISAEFSSMRFVTAWPGFDGYRARIAVSGLRHFEIGLTD
HHCCCCCCCEEEEECHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEECCEEEECCCCC
DLLLDPNDLAQVSRDDCVVLANPSNPTGQALSAGELDQLRQRAGKLLIDETYVDYSSFRA
CEEECCHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEHHHHCHHHHHH
RGLAYGENELVFRSFSKSYGLAGLRLGALFGPSELIAAMKRKQWFCNVGTLDLHALEAAL
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHEECCCCCHHHHHHHHH
DNDRAREAHIAKTLAQRRRVADALRGLGYRVASSEANFVLVENAAGERTLRFLRERGIQV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCHHHHHHHHHCCCEE
KDAGQFGLHHHIRISIGREEDNDRLLAALAEYSDHS
EECCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVGEAMDTEVRAAAQAVCLAFNENPEAVEPRVQAAIAAAAARINRYPFDAEPRVMRKLA
CCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
EHFSCPEDNLMLVRGIDECFDRISAEFSSMRFVTAWPGFDGYRARIAVSGLRHFEIGLTD
HHCCCCCCCEEEEECHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEECCEEEECCCCC
DLLLDPNDLAQVSRDDCVVLANPSNPTGQALSAGELDQLRQRAGKLLIDETYVDYSSFRA
CEEECCHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEHHHHCHHHHHH
RGLAYGENELVFRSFSKSYGLAGLRLGALFGPSELIAAMKRKQWFCNVGTLDLHALEAAL
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHEECCCCCHHHHHHHHH
DNDRAREAHIAKTLAQRRRVADALRGLGYRVASSEANFVLVENAAGERTLRFLRERGIQV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCHHHHHHHHHCCCEE
KDAGQFGLHHHIRISIGREEDNDRLLAALAEYSDHS
EECCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA