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The map label for this gene is sir1 [H]

Identifier: 53718957

GI number: 53718957

Start: 1539904

End: 1541721

Strand: Reverse

Name: sir1 [H]

Synonym: BPSL1319

Alternate gene names: 53718957

Gene position: 1541721-1539904 (Counterclockwise)

Preceding gene: 53718959

Following gene: 53718956

Centisome position: 37.84

GC content: 70.35

Gene sequence:

>1818_bases
ATGTACCGATACACCGAATTCGACAAGGCGTTCGTGCGCAACCGCGCCGCCCAGTTTCGCGACCAGCTCGAACGCTGGCG
GCAAGGCGCGCTCAGCGAGGACGCATTCCGCCCGCTGCGGCTGCAGAACGGCTGGTATGTGCAGCGCCACGCGCCGATGC
TGCGCGTCGCGGTGCCGTACGGCGAGCTGTCGAGCGCGCAGATCCGCATGCTCGCGCGCATCGCGCGCGACTATGACGTG
CCGGAGCCGGCGCGCTACCGCGCCGCCTGCGACGCGCAGGCGCGGCTCGGCACCGTGCGCCTGCCGACGCGCAACGCGCA
TTTCACGACGCGCACGAACGTGCAGTTCAACTGGATCCCGCTCGAGAAGGCGGCCGACGTGATGGACCTGCTCGCGACCG
TCGACATGCACGGCATCCAGACGAGCGGCAACTGCATCCGCAACATCTCGTGCGACGAGCGCGCGGGCGTCGCGCCCGAC
GAAATCGCCGATCCGCGGCCGTTCGCCGAAGTGATGCGCCAATGGACGACGCTGCATCCCGAATTCGCGTTCCTGCCGCG
CAAGTTCAAGATCGCGATCACGGGCGCGGCCGACGATCGCGCGGCGACCGACTGGCACGATGTCGGCTTAAGGCTCGTGC
GCGACGCGGCGGGCGAACTCGGCTTTCGCGTGAGCGTCGGCGGCGGCATGGGGCGCACGCCGATGACGGCCACGCTCGTG
CGCGCATTCGTGCCGTGGCGGCACGTGATGAACTACATCGAGGCGATCGTGCGCGTGTACAACCGCTACGGCCGCCGCGA
CAACAGGTACAAGGCGCGCATCAAGATCCTCGTGAAGGCCGAGGGCCAGCGCTACATCGACGACGTCGACGAGGAATTCC
GGCAGATCGTCGAGCACGACGGCGGCCCGCATACGATCGAGCAGGCGGAGTTCGACCGCGTAGGCGCGTCGTTCGTGCCG
CCCGTGCCGCCGCCGTGCGCGGCCGGGCGCCACGCAAAGACCGATATCGACGCCGACATGGACGCGGCGCTCGCGCGCAT
GCGCACGCTCGCCGGCGCACAGCCCGCGTTCGCGCGCTGGCTCGAGCGCAACGTCGCGCCGCACCGGGATCCCGCGCGGC
GGATCGTCACGCTGTCGTTCAAGCGCAGGCATCAGGCGCCCGGCGATGCGTCGCCCGAGCAGCTCGACGCACTCGCGCAC
CTCGCCGAGCGCTTTTCCGCCGGCGAGGCGCGCGTCACGCACGCGCAGAACGTCGTGCTGCCGTGGGTGCGCGCGATCGA
TCTGCACGCGCTGTGGGAAGCCGCGCGCGACGCGGGCCTCGCGAGCGCGAACGTGCGGCTGTTGACCGACATGATCGCGT
GCCCCGGCGGCGATTTCTGCGCGCTCGCGAACGCGCGCTCGATCCCGATCGCCGATGCGATCGCCGAACGCTTCGACGAT
CTCGACGAGTTGCACGACATCGGCGACGTCGACCTGCACGTGAGCGGCTGCATCAACTCGTGCGGCCATCATCACAGCGG
CCACATCGGCATCCTCGGCGTCGACAAGGACGGCGACGAGTGGTACCAGGTGACGCTCGGCGGCTCCGACGGCACGGCCG
CGAACGGCCCCGCGCAGCCGGGCAAGGTGATCGGGCCGTCGTTCTCGGCCGACGAGATCGTCGACGTCGTCGACGCGCTC
GTCGCCACCTATCTGCGCGTGCGGCGAACCGAGGCCGGGCGCGTCGAACGCTTCATCGACGCGTACCGCCGCGTCGGCCC
CGAGCCCTTCAAGGCCGCCGCGAACGCGGCGCGCCATCCCGAGACGAGTGTCGCATGA

Upstream 100 bases:

>100_bases
GCCGCGCGCCCTACGCTTGGTGATCCTCGCGCCGCCGATGCGGCGCCTCGCAACCGACACGCGCGACCGCGCGCGTGCCG
CCCCACCGCATTGCCCGGCC

Downstream 100 bases:

>100_bases
GCCCGCCGAACCGCATCCGCCTGCTGAGCGCGAGCGCCCACGGCGACGAGACGCGCGCCGCGCCCGCCCGCGACGGCGCG
CCGCTCGCCATCGCGAACGA

Product: putative nitrite/sulfite reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAPMLRVAVPYGELSSAQIRMLARIARDYDV
PEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLATVDMHGIQTSGNCIRNISCDERAGVAPD
EIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRLVRDAAGELGFRVSVGGGMGRTPMTATLV
RAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEEFRQIVEHDGGPHTIEQAEFDRVGASFVP
PVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPARRIVTLSFKRRHQAPGDASPEQLDALAH
LAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMIACPGGDFCALANARSIPIADAIAERFDD
LDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGTAANGPAQPGKVIGPSFSADEIVDVVDAL
VATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA

Sequences:

>Translated_605_residues
MYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAPMLRVAVPYGELSSAQIRMLARIARDYDV
PEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLATVDMHGIQTSGNCIRNISCDERAGVAPD
EIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRLVRDAAGELGFRVSVGGGMGRTPMTATLV
RAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEEFRQIVEHDGGPHTIEQAEFDRVGASFVP
PVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPARRIVTLSFKRRHQAPGDASPEQLDALAH
LAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMIACPGGDFCALANARSIPIADAIAERFDD
LDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGTAANGPAQPGKVIGPSFSADEIVDVVDAL
VATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA
>Mature_605_residues
MYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAPMLRVAVPYGELSSAQIRMLARIARDYDV
PEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIPLEKAADVMDLLATVDMHGIQTSGNCIRNISCDERAGVAPD
EIADPRPFAEVMRQWTTLHPEFAFLPRKFKIAITGAADDRAATDWHDVGLRLVRDAAGELGFRVSVGGGMGRTPMTATLV
RAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEEFRQIVEHDGGPHTIEQAEFDRVGASFVP
PVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARWLERNVAPHRDPARRIVTLSFKRRHQAPGDASPEQLDALAH
LAERFSAGEARVTHAQNVVLPWVRAIDLHALWEAARDAGLASANVRLLTDMIACPGGDFCALANARSIPIADAIAERFDD
LDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGTAANGPAQPGKVIGPSFSADEIVDVVDAL
VATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHPETSVA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 67183; Mature: 67183

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAPMLRVAVPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEECCCEEEEEECC
GELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIP
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCCEEECCCCCCCEEEECCEEEEEEE
LEKAADVMDLLATVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHP
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCC
EFAFLPRKFKIAITGAADDRAATDWHDVGLRLVRDAAGELGFRVSVGGGMGRTPMTATLV
CHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
RAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEEFRQIVEHD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHCC
GGPHTIEQAEFDRVGASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARW
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
LERNVAPHRDPARRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVL
HHHCCCCCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHH
PWVRAIDLHALWEAARDAGLASANVRLLTDMIACPGGDFCALANARSIPIADAIAERFDD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH
LDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGTAANGPAQP
HHHHHCCCCCEEEHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCC
GKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
ETSVA
CCCCC
>Mature Secondary Structure
MYRYTEFDKAFVRNRAAQFRDQLERWRQGALSEDAFRPLRLQNGWYVQRHAPMLRVAVPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEECCCEEEEEECC
GELSSAQIRMLARIARDYDVPEPARYRAACDAQARLGTVRLPTRNAHFTTRTNVQFNWIP
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCCEEECCCCCCCEEEECCEEEEEEE
LEKAADVMDLLATVDMHGIQTSGNCIRNISCDERAGVAPDEIADPRPFAEVMRQWTTLHP
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCC
EFAFLPRKFKIAITGAADDRAATDWHDVGLRLVRDAAGELGFRVSVGGGMGRTPMTATLV
CHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
RAFVPWRHVMNYIEAIVRVYNRYGRRDNRYKARIKILVKAEGQRYIDDVDEEFRQIVEHD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHCC
GGPHTIEQAEFDRVGASFVPPVPPPCAAGRHAKTDIDADMDAALARMRTLAGAQPAFARW
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
LERNVAPHRDPARRIVTLSFKRRHQAPGDASPEQLDALAHLAERFSAGEARVTHAQNVVL
HHHCCCCCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHH
PWVRAIDLHALWEAARDAGLASANVRLLTDMIACPGGDFCALANARSIPIADAIAERFDD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH
LDELHDIGDVDLHVSGCINSCGHHHSGHIGILGVDKDGDEWYQVTLGGSDGTAANGPAQP
HHHHHCCCCCEEEHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCC
GKVIGPSFSADEIVDVVDALVATYLRVRRTEAGRVERFIDAYRRVGPEPFKAAANAARHP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
ETSVA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA