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The map label for this gene is panC

Identifier: 53718633

GI number: 53718633

Start: 1148576

End: 1149415

Strand: Reverse

Name: panC

Synonym: BPSL0991

Alternate gene names: 53718633

Gene position: 1149415-1148576 (Counterclockwise)

Preceding gene: 53718634

Following gene: 53718632

Centisome position: 28.21

GC content: 68.33

Gene sequence:

>840_bases
ATGAAAGTCATCAGCTCGATCCAGGAACTGCGCGACCAGCTGCGCGGCCAGAACCGCACGGCGTTCGTGCCGACGATGGG
CAACCTGCACGACGGGCACCTGTCGCTGATGCGGCTCGCGCGCCAGCACGGCGATCCGGTTGTCGCGAGCATCTTCGTGA
ACCGGCTCCAGTTCGGCCCGAACGAGGACTTCGACCAATACCCGCGCACGCTGCAGGACGACATCGAGAAACTGCAGAAG
GAAAACGTCTACGTGCTGTTCGCGCCGACCGAGCGCGACATGTATCCCGAGCCGCAGGAATATCGCGTGCAGCCGCCGCA
CGATCTCGGCGACATCCTCGAAGGCGAGTTCCGCCCGGGCTTCTTCACCGGCGTGTGCACGGTCGTCACGAAGCTGATGG
CATGCGTGCAGCCGCGCGTCGCGGTGTTCGGCAAGAAGGACTACCAGCAGTTGATGATCGTGCGGCGGATGTGCCAGCAG
CTCGCGCTGCCCGTCGAGATCATCGCGGCCGAGACCGTGCGCGACGCCGACGGCCTCGCGCTGTCGTCGCGCAACCGCTA
TCTGAGCGAGGCCGAGCGCGCGGAGGCGCCCGAGCTCGCGAAGACGCTCGCGCAGGTGCGCTCCGCGGTGCTGGGCGGCG
AGCGCGATCTCGCGGCGATCGAGCAGCGCGCGCTCGCGCACCTCGCCGCGCGCGGCTGGAAGCCCGATTACGTGTCGATC
CGCCGGCGCGCGAACCTCGTCGCGCCGAGCGCGGCGCACATCGAAGCGGGCGAGCCGCTCGTCGTGCTCACGGCCGCGAA
GCTCGGCGCGACGCGCCTCATCGACAATCTGGAAATCTGA

Upstream 100 bases:

>100_bases
ATCGCCGACGCTCGACGCCCTGCGCGTTCCGGCCACGACGATCCCGACCACGCCGCCCTCGCGCGGCCAACGCGCGCACC
GCGCGAGGAACCGCCCACTC

Downstream 100 bases:

>100_bases
CGGCCGGCCACGCAGCCGCCGCCTTTCGTCTGGTAGCACCAAGGGAGCCATCATGCAGCGCCACATGCTGAAATCGAAGA
TCCACCGCGCGGCGGTCACG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDQYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVEIIAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSI
RRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI

Sequences:

>Translated_279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDQYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVEIIAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSI
RRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI
>Mature_279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDQYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVEIIAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSI
RRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=282, Percent_Identity=44.6808510638298, Blast_Score=220, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322046, Length=295, Percent_Identity=36.9491525423729, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_BURM7 (A3MLN2)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001081168.1
- ProteinModelPortal:   A3MLN2
- SMR:   A3MLN2
- GeneID:   4894719
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_1624
- TIGR:   BMA10247_1624
- HOGENOM:   HBG428839
- OMA:   RLIDNFT
- ProtClustDB:   PRK00380
- BioCyc:   BMAL320389:BMA10247_1624-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 31207; Mature: 31207

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: ACT_SITE 33-33 BINDING 57-57 BINDING 57-57 BINDING 150-150 BINDING 173-173

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDQYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPG
CCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHCCCCCCCCHHHHHCCCCCCC
FFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIIAAETVRDADGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSI
ECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
RRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI
HHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDQYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPG
CCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHCCCCCCCCHHHHHCCCCCCC
FFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIIAAETVRDADGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSI
ECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
RRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI
HHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA