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The map label for this gene is cbl [H]

Identifier: 53718597

GI number: 53718597

Start: 1112760

End: 1113701

Strand: Reverse

Name: cbl [H]

Synonym: BPSL0955

Alternate gene names: 53718597

Gene position: 1113701-1112760 (Counterclockwise)

Preceding gene: 53718604

Following gene: 53718596

Centisome position: 27.33

GC content: 64.54

Gene sequence:

>942_bases
ATGAACCTGCACCAATTTCGCTTCGTACGCGAGGCCGTCCGGCAGAATTTCAACCTCACGGAAGCCGCGAAGGCGCTGTA
CACGTCGCAGCCCGGGGTTTCGAAGGCGATCATCGAGCTCGAGGACGAGCTCGGCGTCGAGATCTTCACCCGCCACGGCA
AGCGCGTGCGCTCGCTGACCGAGCCGGGCAGGATCATTCTCGCGTCGGTCGAGCGGATCCTCCAGGAGGTCGAAAGCCTT
AAAAGGGTCGGAAAAGATTACGCGGCGCAGGATCAGGGCAACCTGACGATCGCCGCGACGCACACGCAGGCCCGCTACTC
GCTGCCCGCCGCGATCGCCGAGTTCAAGAAGCGCTTTCCGAAAGTCCATCTGTCGATCCTGCAGGGCAGCCCGACGCAGG
TCGCCGAAATGGTGATCCACGATCAGGCGGACCTCGCGATCGCGACGGAGGCGATCGCCGACTACAAGGAGCTCGTGTCG
CTGCCCTGCTTCCAGTGGCACCACGCGGCCGTCGTGCCGGCCGATCACCCGCTGCTCGAGCGCAAGCCGCTGTCGCTCGA
CGATCTCGCGCAGTTCCCGCTCATCACGTACGACGATGCGTTCGCCGGCCGCAAGAAGATCAATCAGGCATTCGCGCTGC
ATCGCCTGACGCCCGACATCGTGCTCGAGGCGATCGACGCGGACGTGATCAAGACCTACGTCGAGCTCGGGCTCGGCGTC
GGCATCATGGCCGACATCGCCTTCAACCCGGAGCGCGACCGCAACCTGCGCGCGATTGCGGTCGGCCATCTGTTCGGCAG
CAACGTGACGCGCGTCGCGCTCAAGCAGGGCGCGTATCTGCGCGGCTATATCTATACGCTCGTCGAGCTGCTGTCGCCGA
CGCTCAATCGCAAGCTCGTCGAAACGGCGCTCAAGGGCGAGGCCGAAACCTACGAGCTGTGA

Upstream 100 bases:

>100_bases
TTACAGATATCCATATTTGAAAAACACGGGGCAATCGTAATAAACTCCCTTTATATTTCAAACGACTAAAAAATTCTGTT
GATATGCGGAAGGGTTATAA

Downstream 100 bases:

>100_bases
CGCGCGCCGCTGGAGGACCGTGCCGCGCGCACCGATCGGACGGTCGGCGTCGAGCTGTCGACGCCCCCCGGCCCGGCGCA
CGCCGACAACCGCGCAGCCG

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHAAVVPADHPLLERKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
GIMADIAFNPERDRNLRAIAVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLVETALKGEAETYEL

Sequences:

>Translated_313_residues
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHAAVVPADHPLLERKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
GIMADIAFNPERDRNLRAIAVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLVETALKGEAETYEL
>Mature_313_residues
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHAAVVPADHPLLERKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
GIMADIAFNPERDRNLRAIAVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLVETALKGEAETYEL

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=308, Percent_Identity=45.4545454545455, Blast_Score=290, Evalue=6e-80,
Organism=Escherichia coli, GI1787530, Length=304, Percent_Identity=44.7368421052632, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI157672245, Length=213, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=26.1224489795918, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788481, Length=247, Percent_Identity=27.5303643724696, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788887, Length=249, Percent_Identity=28.5140562248996, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790399, Length=255, Percent_Identity=24.3137254901961, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=28.8590604026846, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787879, Length=240, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082132, Length=147, Percent_Identity=25.8503401360544, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=23.8095238095238, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34874; Mature: 34874

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHC
EPGRIILASVERILQEVESLKRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
KVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVSLPCFQWHHAAVVPADHPLLE
CEEEHEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
RKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
CCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
GIMADIAFNPERDRNLRAIAVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLV
HHEEEEECCCCCCCCEEEEEEEHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
ETALKGEAETYEL
HHHHCCCCCCCCC
>Mature Secondary Structure
MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHC
EPGRIILASVERILQEVESLKRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
KVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVSLPCFQWHHAAVVPADHPLLE
CEEEHEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
RKPLSLDDLAQFPLITYDDAFAGRKKINQAFALHRLTPDIVLEAIDADVIKTYVELGLGV
CCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
GIMADIAFNPERDRNLRAIAVGHLFGSNVTRVALKQGAYLRGYIYTLVELLSPTLNRKLV
HHEEEEECCCCCCCCEEEEEEEHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
ETALKGEAETYEL
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]