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The map label for this gene is ygfU [H]

Identifier: 53718455

GI number: 53718455

Start: 949498

End: 950943

Strand: Reverse

Name: ygfU [H]

Synonym: BPSL0817

Alternate gene names: 53718455

Gene position: 950943-949498 (Counterclockwise)

Preceding gene: 53718457

Following gene: 53718451

Centisome position: 23.34

GC content: 64.8

Gene sequence:

>1446_bases
GTGCTCTTGTTGCGATTCGTCAATGCGCATAACGTTGAACCACCGTCAAAACAAAATCATGGAGTGAGACAGATGCAATC
GAACACGGTCCATCCGTGCGACGAGGTGTTACCGTCCGGCAAGCTGCTGACGCTCGGGCTGCAGCACGTTCTCGTCATGT
ACGCAGGCGCCGTCGCGGTGCCGCTCATCGTCGGCGGGGCGCTCAAGCTGCCGAAAGACCAGATCGCGTTCCTCATCAGC
GCGGACCTGTTCGCGTGCGGAATCGCGACACTGATCCAGACGCTCGGCGTGTGGCTCTTCGGCATCCGCCTGCCCGTCAT
CATGGGCTGCACGTTCGCGGCGGTCGGCCCGATGATCGCGATCGGCACGAATCCCGGCCTCGGCATCCTCGATATCTTCG
GCTCGACGATCGCCGCGGGCGCGATCGGCATCGTGCTCGCGCCGATGATCGGCAAGCTGCTGCGCTTCTTTCCGCCCGTC
GTCGTCGGCACCGTGATCTCGGTGATCGGCCTGTCGCTGATGGAAGTCGGCATCAACTGGGCGGCGGGCGGCGTCGGCAA
TCCGAACTACGGCGACCCGGTCTATCTCGGCCTGTCGTTCATCGTGCTCGCACTGATCCTCGCCATCAACAAGTTCGGCC
GCGGCTTCGTCGCGAACATCTCGGTGCTGCTCGGCATGATCGCGGGCTTCGCGATCGCGTTCGCCGCGGGCCGCGTGAAC
ACCGACGGCGTCGCGGCGGCGCCGTGGGTCGGCTTCGTCGCGCCGTTCCATTTCGGACTCCCGCATTTCGATCCGCTATC
GATCGCGACGATGGTGATCGTGATGTTCGTCACGTTCATCGAATCGACCGGGATGTTCCTCGCGGTCGGCGACATGGTCG
AGCGGCCCGTCGATCAGGAAACGCTCGTGCGCGGGCTGCGCGTCGACGGGCTCGGCACGCTGATCGGCGGCATCTTCAAT
TCGTTTCCGCACACGTCGTTCTCGCAGAACGTCGGGTTGATCGGCGTGACGGGCGTGAAGAGCCGCTTCGTCTGCGCGAC
GGGCGGCATGATCCTCGTGCTGCTCGGGCTCTTTCCGAAGATGGCGCAGCTCGTCGCGTCGGTGCCGCCGTTCGTGCTCG
GCGGCGCGGGCATCGTGATGTTCGGAATGGTGGCCGCCAACGGCGTGAAGGTGCTGTCGAAGGTCGACTTCGTGCGCAAC
CACCACAATCTGTTCATCGTCGCGGTGAGCGTCGGCCTCGGGCTCGTGCCCGTCGTGTCGCCGAACTTCTTCTCGAAGCT
CCCCGCCGCGTTCGCGCCGATCCTCCACAGCGGGATCCTGCTCGCGTCGGTGTCGGCCGTCGTGCTCAATATCGTGTTCA
ACGGCATGAAGGGCGAGAAGGATGCGCGCTGCGACATTCGCCGCGCGGGACGCGATTTCGACGGGCAGCCGGCCGATCTG
CATTGA

Upstream 100 bases:

>100_bases
AACGGCGACACTCACCCGCACGCGCAGGTCCCGAGATGAACGCATCGCTCCGATACACCCGGCGCGCATATCGACGCAGC
GAAGCACGGAATAGGAACCG

Downstream 100 bases:

>100_bases
GCGGGCGCCGCGGCTGCTCGGCCGGCGACGCGGCGACGCTCGCGATCGAACGGGCGCGCTGTCTCACGGCGCGCCGTCGA
TGTCGAACGTCGATCCCGCA

Product: putative permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MLLLRFVNAHNVEPPSKQNHGVRQMQSNTVHPCDEVLPSGKLLTLGLQHVLVMYAGAVAVPLIVGGALKLPKDQIAFLIS
ADLFACGIATLIQTLGVWLFGIRLPVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGAIGIVLAPMIGKLLRFFPPV
VVGTVISVIGLSLMEVGINWAAGGVGNPNYGDPVYLGLSFIVLALILAINKFGRGFVANISVLLGMIAGFAIAFAAGRVN
TDGVAAAPWVGFVAPFHFGLPHFDPLSIATMVIVMFVTFIESTGMFLAVGDMVERPVDQETLVRGLRVDGLGTLIGGIFN
SFPHTSFSQNVGLIGVTGVKSRFVCATGGMILVLLGLFPKMAQLVASVPPFVLGGAGIVMFGMVAANGVKVLSKVDFVRN
HHNLFIVAVSVGLGLVPVVSPNFFSKLPAAFAPILHSGILLASVSAVVLNIVFNGMKGEKDARCDIRRAGRDFDGQPADL
H

Sequences:

>Translated_481_residues
MLLLRFVNAHNVEPPSKQNHGVRQMQSNTVHPCDEVLPSGKLLTLGLQHVLVMYAGAVAVPLIVGGALKLPKDQIAFLIS
ADLFACGIATLIQTLGVWLFGIRLPVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGAIGIVLAPMIGKLLRFFPPV
VVGTVISVIGLSLMEVGINWAAGGVGNPNYGDPVYLGLSFIVLALILAINKFGRGFVANISVLLGMIAGFAIAFAAGRVN
TDGVAAAPWVGFVAPFHFGLPHFDPLSIATMVIVMFVTFIESTGMFLAVGDMVERPVDQETLVRGLRVDGLGTLIGGIFN
SFPHTSFSQNVGLIGVTGVKSRFVCATGGMILVLLGLFPKMAQLVASVPPFVLGGAGIVMFGMVAANGVKVLSKVDFVRN
HHNLFIVAVSVGLGLVPVVSPNFFSKLPAAFAPILHSGILLASVSAVVLNIVFNGMKGEKDARCDIRRAGRDFDGQPADL
H
>Mature_481_residues
MLLLRFVNAHNVEPPSKQNHGVRQMQSNTVHPCDEVLPSGKLLTLGLQHVLVMYAGAVAVPLIVGGALKLPKDQIAFLIS
ADLFACGIATLIQTLGVWLFGIRLPVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGAIGIVLAPMIGKLLRFFPPV
VVGTVISVIGLSLMEVGINWAAGGVGNPNYGDPVYLGLSFIVLALILAINKFGRGFVANISVLLGMIAGFAIAFAAGRVN
TDGVAAAPWVGFVAPFHFGLPHFDPLSIATMVIVMFVTFIESTGMFLAVGDMVERPVDQETLVRGLRVDGLGTLIGGIFN
SFPHTSFSQNVGLIGVTGVKSRFVCATGGMILVLLGLFPKMAQLVASVPPFVLGGAGIVMFGMVAANGVKVLSKVDFVRN
HHNLFIVAVSVGLGLVPVVSPNFFSKLPAAFAPILHSGILLASVSAVVLNIVFNGMKGEKDARCDIRRAGRDFDGQPADL
H

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=467, Percent_Identity=27.4089935760171, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI40316845, Length=467, Percent_Identity=27.4089935760171, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI44680145, Length=484, Percent_Identity=25.8264462809917, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI44680143, Length=488, Percent_Identity=25.6147540983607, Blast_Score=109, Evalue=7e-24,
Organism=Escherichia coli, GI87082181, Length=437, Percent_Identity=59.0389016018307, Blast_Score=520, Evalue=1e-148,
Organism=Escherichia coli, GI1790087, Length=454, Percent_Identity=31.4977973568282, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87082178, Length=457, Percent_Identity=29.1028446389497, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788843, Length=384, Percent_Identity=28.3854166666667, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI87081818, Length=412, Percent_Identity=29.6116504854369, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17558856, Length=496, Percent_Identity=26.4112903225806, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541904, Length=458, Percent_Identity=22.9257641921397, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17542262, Length=438, Percent_Identity=24.2009132420091, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=195, Percent_Identity=29.7435897435897, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=194, Percent_Identity=28.3505154639175, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356175, Length=475, Percent_Identity=25.0526315789474, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50248; Mature: 50248

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLRFVNAHNVEPPSKQNHGVRQMQSNTVHPCDEVLPSGKLLTLGLQHVLVMYAGAVAV
CEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
PLIVGGALKLPKDQIAFLISADLFACGIATLIQTLGVWLFGIRLPVIMGCTFAAVGPMIA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
IGTNPGLGILDIFGSTIAAGAIGIVLAPMIGKLLRFFPPVVVGTVISVIGLSLMEVGINW
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
AAGGVGNPNYGDPVYLGLSFIVLALILAINKFGRGFVANISVLLGMIAGFAIAFAAGRVN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TDGVAAAPWVGFVAPFHFGLPHFDPLSIATMVIVMFVTFIESTGMFLAVGDMVERPVDQE
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCHH
TLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFVCATGGMILVLLGLFPK
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHH
MAQLVASVPPFVLGGAGIVMFGMVAANGVKVLSKVDFVRNHHNLFIVAVSVGLGLVPVVS
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCC
PNFFSKLPAAFAPILHSGILLASVSAVVLNIVFNGMKGEKDARCDIRRAGRDFDGQPADL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCC
H
C
>Mature Secondary Structure
MLLLRFVNAHNVEPPSKQNHGVRQMQSNTVHPCDEVLPSGKLLTLGLQHVLVMYAGAVAV
CEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
PLIVGGALKLPKDQIAFLISADLFACGIATLIQTLGVWLFGIRLPVIMGCTFAAVGPMIA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
IGTNPGLGILDIFGSTIAAGAIGIVLAPMIGKLLRFFPPVVVGTVISVIGLSLMEVGINW
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
AAGGVGNPNYGDPVYLGLSFIVLALILAINKFGRGFVANISVLLGMIAGFAIAFAAGRVN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TDGVAAAPWVGFVAPFHFGLPHFDPLSIATMVIVMFVTFIESTGMFLAVGDMVERPVDQE
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCHH
TLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFVCATGGMILVLLGLFPK
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHH
MAQLVASVPPFVLGGAGIVMFGMVAANGVKVLSKVDFVRNHHNLFIVAVSVGLGLVPVVS
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCC
PNFFSKLPAAFAPILHSGILLASVSAVVLNIVFNGMKGEKDARCDIRRAGRDFDGQPADL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]