Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 53718346

GI number: 53718346

Start: 801764

End: 803647

Strand: Reverse

Name: zraS [C]

Synonym: BPSL0703

Alternate gene names: 53718346

Gene position: 803647-801764 (Counterclockwise)

Preceding gene: 53718347

Following gene: 53718344

Centisome position: 19.72

GC content: 69.85

Gene sequence:

>1884_bases
ATGCATGGCACCTTCAATCTGCCGCTCGTCGCGCTGTCGCTCGCGATCGCAACGCTTGCGTCATACACGGCGCTCGACCT
GAGCGCGCTCATCACGCTCCTCGACCAGCCCCGGATGCGCCGCGCGTGGCTCGCGGGCGGCGCGGCCGCGATGGGCACGG
GCATCTGGGCGATGCACTTCGTCGGCATGCTCGCGTTCTCGCTGCCGATCCCGCTCGGCTACGATTTCGGCCACACGTTC
GCGTCGCTCGCGATCGCGGTGGTCGTGTCGTACTTCGCGCTGAACGCGGTCACGCGCGCCGCGCTCACGCGCGAGCGGCT
CGCGATCGGCGGCGTGCTGATGGGGCTCGGCATCGCGGGCATGCATTACACCGGGATGAGCGCGCTGCGGATGCAGCCCG
CGATCGCCTATGACTTCACGCTGTTCGTCGCATCGATCGCGATCGCGATCGGCGCGTCGACGACCGCGCTGTGGATCGCG
CACCGCTTGAGCAACGAGAACGAGCCGCGCGTGCTCATGAAGCGGATCGCCGCGGCGGGCGTGATGGGGCTCGCGATCAC
CGGCATGCACTACACGGGCATGGCGGCCGCGCATTTCGGGGCGAACGCCGTATGCGGCGCGGCGGGCGAGATCAGCGGCG
CGTGGCTCGGCGCGACGATCGCCCTCTTTACCGTGACGATCCTGAGCGCGACGCTCGTCGTCTCGCGCTTCGATGCGCGC
ACCGCGTTCCTGCGCGGGATGACCGATGCGCTCGAGGAACTCGTCGCGAAGCGCACGAGCGAGCTCGAGGGCGCGCTGCG
GCAATACGAGCGCACGACGCACGTGCTGCAGCGCACGCGCCGGAAAATGGAGCAGGAGATCGACGAGCGCAAGGCCGCGC
AGGCGCGCCTCGAGCACGAGAAGGACGAGCAGCGCCGCCTGATCCGGCGGCTCGAGGAAACGCACGTGCAGTTGCTGCAA
TCGGAGAAGCTCGCGTCGATCGGCCAGCTCGCGGCGGGCGTCGCGCACGAGATCAACAACCCGATCGGCTTCGTCAACGC
GAATCTGAACACGCTGAGGAGCTGGGTCCAGGGCCTGCTCGACGTGATCGCCGTGCAGGAGGCGCTGACGGGCACGCTCG
CGGCCGATGCGCGCGCGCCGCTCGCCGCGGTGGCGCGCGACATCGATCTCGATTACGTGCGCGGCGACATCCTCGCGCTC
ATCGACGAATCGATCGACGGCGCGATGCGCGTGCGGCGCATCGTCTGCGACCTGCGCGACTTCTCGCGGCCGAGCGGCGA
CGCCTGGGCGTTCGCCGATCTGCACGCGAGCCTCGAGAGCACGCTGAACGTCGTCCACAACGAGCTCAAGTACAAGGCGG
ACATCGTGCGCGAGTACGGCGTGCTGCCGCTCGTCGAATGCAACGCCGCGCAGTTGAGCCAGGTGTTCATGAACCTGCTC
GTCAACGCCGCGCAGTCGATCGGCACGCACGGCACGATCACGATTCGCACGACGCACGACGGCGACACCGTGTCGATCTC
GATCGCCGACACAGGCGCCGGCATACCGGAGGACGCGATCGGCCGGATCTTCGATCCGTTCTTCACGACGAAGCCGGTCG
GCCAGGGCACGGGGCTCGGGCTGTCGATCTCGCACGGCATCGTCGAGCATCATGGCGGGCGCATCGACGTCGAGAGCCAC
GTCGGCCGCGGCTCGACGTTGACGGTCACGCTGCCGGTCCGGCGCAAGCCCGAGCCGGCCGCGCGAACGACCGCGGGCGA
CGGCGCGAACAACGTGAACGACGTGCACGCCACGAACGGCGCGAGCGCCGCGCGCGACGCGGCCCGCGCGATCGAGCGCG
CCGCCGCGTCGGCCGCGCCGCTTACGCGCGGCGCGGCTTGCTGA

Upstream 100 bases:

>100_bases
CAGACGACGACGCTAGCCGAAGCCGCGGCGAGCGCCGGGCGCGAATGCTGACGCGCGCGTCGCACCCGCCGCCCGCGCGC
ATCGGGAAAAACCCACGTCC

Downstream 100 bases:

>100_bases
GCACGATCGTCTCGAACAGTTCGTACTCGGCCGTCGGATGCTGGTCGGCGCCCGGCGCGTGATAGTAGTTCACGGTGATC
GTCGAGCGGCCGCCGTGCTC

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MHGTFNLPLVALSLAIATLASYTALDLSALITLLDQPRMRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDFGHTF
ASLAIAVVVSYFALNAVTRAALTRERLAIGGVLMGLGIAGMHYTGMSALRMQPAIAYDFTLFVASIAIAIGASTTALWIA
HRLSNENEPRVLMKRIAAAGVMGLAITGMHYTGMAAAHFGANAVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHEKDEQRRLIRRLEETHVQLLQ
SEKLASIGQLAAGVAHEINNPIGFVNANLNTLRSWVQGLLDVIAVQEALTGTLAADARAPLAAVARDIDLDYVRGDILAL
IDESIDGAMRVRRIVCDLRDFSRPSGDAWAFADLHASLESTLNVVHNELKYKADIVREYGVLPLVECNAAQLSQVFMNLL
VNAAQSIGTHGTITIRTTHDGDTVSISIADTGAGIPEDAIGRIFDPFFTTKPVGQGTGLGLSISHGIVEHHGGRIDVESH
VGRGSTLTVTLPVRRKPEPAARTTAGDGANNVNDVHATNGASAARDAARAIERAAASAAPLTRGAAC

Sequences:

>Translated_627_residues
MHGTFNLPLVALSLAIATLASYTALDLSALITLLDQPRMRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDFGHTF
ASLAIAVVVSYFALNAVTRAALTRERLAIGGVLMGLGIAGMHYTGMSALRMQPAIAYDFTLFVASIAIAIGASTTALWIA
HRLSNENEPRVLMKRIAAAGVMGLAITGMHYTGMAAAHFGANAVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHEKDEQRRLIRRLEETHVQLLQ
SEKLASIGQLAAGVAHEINNPIGFVNANLNTLRSWVQGLLDVIAVQEALTGTLAADARAPLAAVARDIDLDYVRGDILAL
IDESIDGAMRVRRIVCDLRDFSRPSGDAWAFADLHASLESTLNVVHNELKYKADIVREYGVLPLVECNAAQLSQVFMNLL
VNAAQSIGTHGTITIRTTHDGDTVSISIADTGAGIPEDAIGRIFDPFFTTKPVGQGTGLGLSISHGIVEHHGGRIDVESH
VGRGSTLTVTLPVRRKPEPAARTTAGDGANNVNDVHATNGASAARDAARAIERAAASAAPLTRGAAC
>Mature_627_residues
MHGTFNLPLVALSLAIATLASYTALDLSALITLLDQPRMRRAWLAGGAAAMGTGIWAMHFVGMLAFSLPIPLGYDFGHTF
ASLAIAVVVSYFALNAVTRAALTRERLAIGGVLMGLGIAGMHYTGMSALRMQPAIAYDFTLFVASIAIAIGASTTALWIA
HRLSNENEPRVLMKRIAAAGVMGLAITGMHYTGMAAAHFGANAVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHEKDEQRRLIRRLEETHVQLLQ
SEKLASIGQLAAGVAHEINNPIGFVNANLNTLRSWVQGLLDVIAVQEALTGTLAADARAPLAAVARDIDLDYVRGDILAL
IDESIDGAMRVRRIVCDLRDFSRPSGDAWAFADLHASLESTLNVVHNELKYKADIVREYGVLPLVECNAAQLSQVFMNLL
VNAAQSIGTHGTITIRTTHDGDTVSISIADTGAGIPEDAIGRIFDPFFTTKPVGQGTGLGLSISHGIVEHHGGRIDVESH
VGRGSTLTVTLPVRRKPEPAARTTAGDGANNVNDVHATNGASAARDAARAIERAAASAAPLTRGAAC

Specific function: Member Of The Two-Component Regulatory System Zras/Zrar. May Function As A Membrane-Associated Protein Kinase That Phosphorylates Zrar In Response To High Concentrations Of Zinc Or Lead In The Medium. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=279, Percent_Identity=34.4086021505376, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788549, Length=265, Percent_Identity=33.5849056603774, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI145693157, Length=326, Percent_Identity=26.0736196319018, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=27.5303643724696, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790300, Length=286, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=112, Percent_Identity=33.9285714285714, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=26.6094420600858, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788393, Length=109, Percent_Identity=33.9449541284404, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 66735; Mature: 66735

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50924 MHYT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGTFNLPLVALSLAIATLASYTALDLSALITLLDQPRMRRAWLAGGAAAMGTGIWAMHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
VGMLAFSLPIPLGYDFGHTFASLAIAVVVSYFALNAVTRAALTRERLAIGGVLMGLGIAG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHYTGMSALRMQPAIAYDFTLFVASIAIAIGASTTALWIAHRLSNENEPRVLMKRIAAAG
HHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
VMGLAITGMHYTGMAAAHFGANAVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
HHHHHEECCCHHCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KDEQRRLIRRLEETHVQLLQSEKLASIGQLAAGVAHEINNPIGFVNANLNTLRSWVQGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
DVIAVQEALTGTLAADARAPLAAVARDIDLDYVRGDILALIDESIDGAMRVRRIVCDLRD
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSRPSGDAWAFADLHASLESTLNVVHNELKYKADIVREYGVLPLVECNAAQLSQVFMNLL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
VNAAQSIGTHGTITIRTTHDGDTVSISIADTGAGIPEDAIGRIFDPFFTTKPVGQGTGLG
HHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCCCC
LSISHGIVEHHGGRIDVESHVGRGSTLTVTLPVRRKPEPAARTTAGDGANNVNDVHATNG
EECCCCHHHHCCCEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASAARDAARAIERAAASAAPLTRGAAC
CHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHGTFNLPLVALSLAIATLASYTALDLSALITLLDQPRMRRAWLAGGAAAMGTGIWAMHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
VGMLAFSLPIPLGYDFGHTFASLAIAVVVSYFALNAVTRAALTRERLAIGGVLMGLGIAG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHYTGMSALRMQPAIAYDFTLFVASIAIAIGASTTALWIAHRLSNENEPRVLMKRIAAAG
HHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
VMGLAITGMHYTGMAAAHFGANAVCGAAGEISGAWLGATIALFTVTILSATLVVSRFDAR
HHHHHEECCCHHCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFLRGMTDALEELVAKRTSELEGALRQYERTTHVLQRTRRKMEQEIDERKAAQARLEHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KDEQRRLIRRLEETHVQLLQSEKLASIGQLAAGVAHEINNPIGFVNANLNTLRSWVQGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
DVIAVQEALTGTLAADARAPLAAVARDIDLDYVRGDILALIDESIDGAMRVRRIVCDLRD
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSRPSGDAWAFADLHASLESTLNVVHNELKYKADIVREYGVLPLVECNAAQLSQVFMNLL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
VNAAQSIGTHGTITIRTTHDGDTVSISIADTGAGIPEDAIGRIFDPFFTTKPVGQGTGLG
HHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCCCC
LSISHGIVEHHGGRIDVESHVGRGSTLTVTLPVRRKPEPAARTTAGDGANNVNDVHATNG
EECCCCHHHHCCCEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASAARDAARAIERAAASAAPLTRGAAC
CHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]