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The map label for this gene is 53718069

Identifier: 53718069

GI number: 53718069

Start: 468950

End: 469729

Strand: Reverse

Name: 53718069

Synonym: BPSL0430

Alternate gene names: NA

Gene position: 469729-468950 (Counterclockwise)

Preceding gene: 53718071

Following gene: 53718067

Centisome position: 11.53

GC content: 69.36

Gene sequence:

>780_bases
ATGGCCTTGCTGCCCGGCACCCTCACCATTCCCGACAGGCGCGAACACGCGCGGCACCGGCTGCTGATGTTCCATCACGC
ATGCGGCTCCGCGACGAACTATTTTCGATGGGCCGCCGCGTTTGCGCCGCATATCGAAGTCTGGCTCGTCGAGCTGCCGG
GGCGAGGCCGCAGCCTCAGGCACGGTGCGTTCGACGCACTGCCGCCGCTGCGCGACTACCTGCGCGAGCTCGCCCCCGAA
CTCCCCGCCGAATATTCGATCTTCGGCCACAGCATGGGCGCGCTCGTCGCGTACTGCTTCGCGCAAGACATGATGCAGCT
CGGGCGCGCGCCGCGCTGGCTCGGCGTATCGGGCGCCGATTCACCGTTCGCCGCGTCGCGGCGCCGCGCGTTCCCGGTCC
ATCAGCGCCCCGATGCGGCGATCGTCGAGCACCTCGCGACGCTCGGCGGCACGCCGCCTGAAGTTTTCGCGCACGACGAG
TTGCGCGCGATGCTGCTGCAACTCGCGAAGGCCGACTTCCGGATTGTCGAGGCGTTCTTTCCGCTCGCGTCGGCCACGCC
GCTGCCCGTGCCCGTCACGGTCTTCGCCGGCGCGCAAGACACGGTGCTGTCCGAGGGCGGGCTGCAGGACTGGCAGCGCG
CGTCGACGCTGCCGATCGAGCGCGAAACGTTCGACGGCGGGCATTTCTACCTGCTCGATACGCCGTGCGCCATCCATGAC
GCGATTGGCGCGGCGCTGGCGAGACACGAACGGCAGGCGAGCGTCCCCGCCGTTCTATAG

Upstream 100 bases:

>100_bases
GCCCTTCGGCGGGCATCGCCCCGCGTCCCGCGCCCCGAGCATTCGCGGCGCCGCCGGACCGCCCGAAGACTTGCCTTCCC
TGACACTGGAGCGATCGCGC

Downstream 100 bases:

>100_bases
CCGAAGGGGAAAAGCGGCGGCCGGCGCGCGCGCCGCGGTGCGCAGCGCATCGTGCCGGCCGGGCGCGCGATCGCGCGCCT
GCCCCCTCCCGAAGCCCCGC

Product: putative thioesterase

Products: NA

Alternate protein names: ORF-1; Protein X [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MALLPGTLTIPDRREHARHRLLMFHHACGSATNYFRWAAAFAPHIEVWLVELPGRGRSLRHGAFDALPPLRDYLRELAPE
LPAEYSIFGHSMGALVAYCFAQDMMQLGRAPRWLGVSGADSPFAASRRRAFPVHQRPDAAIVEHLATLGGTPPEVFAHDE
LRAMLLQLAKADFRIVEAFFPLASATPLPVPVTVFAGAQDTVLSEGGLQDWQRASTLPIERETFDGGHFYLLDTPCAIHD
AIGAALARHERQASVPAVL

Sequences:

>Translated_259_residues
MALLPGTLTIPDRREHARHRLLMFHHACGSATNYFRWAAAFAPHIEVWLVELPGRGRSLRHGAFDALPPLRDYLRELAPE
LPAEYSIFGHSMGALVAYCFAQDMMQLGRAPRWLGVSGADSPFAASRRRAFPVHQRPDAAIVEHLATLGGTPPEVFAHDE
LRAMLLQLAKADFRIVEAFFPLASATPLPVPVTVFAGAQDTVLSEGGLQDWQRASTLPIERETFDGGHFYLLDTPCAIHD
AIGAALARHERQASVPAVL
>Mature_258_residues
ALLPGTLTIPDRREHARHRLLMFHHACGSATNYFRWAAAFAPHIEVWLVELPGRGRSLRHGAFDALPPLRDYLRELAPEL
PAEYSIFGHSMGALVAYCFAQDMMQLGRAPRWLGVSGADSPFAASRRRAFPVHQRPDAAIVEHLATLGGTPPEVFAHDEL
RAMLLQLAKADFRIVEAFFPLASATPLPVPVTVFAGAQDTVLSEGGLQDWQRASTLPIERETFDGGHFYLLDTPCAIHDA
IGAALARHERQASVPAVL

Specific function: Probable thioesterase involved in the biosynthesis of candicidin. Could release the macrolide ring from the polyketide synthase [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR010693
- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF06902 DUF1271; PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28454; Mature: 28323

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLPGTLTIPDRREHARHRLLMFHHACGSATNYFRWAAAFAPHIEVWLVELPGRGRSLR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCC
HGAFDALPPLRDYLRELAPELPAEYSIFGHSMGALVAYCFAQDMMQLGRAPRWLGVSGAD
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
SPFAASRRRAFPVHQRPDAAIVEHLATLGGTPPEVFAHDELRAMLLQLAKADFRIVEAFF
CCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLASATPLPVPVTVFAGAQDTVLSEGGLQDWQRASTLPIERETFDGGHFYLLDTPCAIHD
HHCCCCCCCCCEEEECCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHH
AIGAALARHERQASVPAVL
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALLPGTLTIPDRREHARHRLLMFHHACGSATNYFRWAAAFAPHIEVWLVELPGRGRSLR
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCC
HGAFDALPPLRDYLRELAPELPAEYSIFGHSMGALVAYCFAQDMMQLGRAPRWLGVSGAD
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
SPFAASRRRAFPVHQRPDAAIVEHLATLGGTPPEVFAHDELRAMLLQLAKADFRIVEAFF
CCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLASATPLPVPVTVFAGAQDTVLSEGGLQDWQRASTLPIERETFDGGHFYLLDTPCAIHD
HHCCCCCCCCCEEEECCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHH
AIGAALARHERQASVPAVL
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]