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The map label for this gene is argS [H]

Identifier: 53718023

GI number: 53718023

Start: 414152

End: 415936

Strand: Reverse

Name: argS [H]

Synonym: BPSL0383

Alternate gene names: 53718023

Gene position: 415936-414152 (Counterclockwise)

Preceding gene: 53718025

Following gene: 53718022

Centisome position: 10.21

GC content: 68.29

Gene sequence:

>1785_bases
ATGCTGCCTGCTCAAAAACATACTCTCGAAACCCTGCTCGAAAACAGCGTGAAGCAGGTCGTCCAGGCGTCGAAGGGCGA
CGCCGACGCCGCGTTCGTCCTCCCCGCGATCGCGCTCGAGCGCCCGAAGGTCGCCGCGCACGGCGACGTCGCGTGCAACG
TCGCGCTGCAGCTCGCGAAGCCGCTCGGCGCGAATCCGCGCCAGCTCGCCGAACAGATCGTCGCCGCGCTCACCGCGCAG
CCCGAGGCGGCGGGCCTCGTCGACGCGGCCGAGATCGCCGGGCCCGGCTTCATCAACCTGCGCCTCACGCCCGCGTCGAA
GCAGGCGGTGATCGGCGCGGTGCTCGCGCAAGGCCGCGCGTTCGGCGCGTCCGAGCGCGACCACGGCAAGCGCGTGCTGC
TCGAATTCGTGTCCGCGAACCCGACGGGCCCGCTGCACGTCGGCCACGGCCGGCAGGCCGCGCTCGGCGACGCGCTCGCG
AACGTGCTCGCGAGCCAGGGCTACGCGGTGCACCGCGAGTTCTACTACAACGACGCCGGCGTGCAAATCGGCAATCTCGC
GATCTCGACGCAGGCGCGCGCCCGCGGCCTGAAGCCCGGCGACGCCGGCTGGCCGGAGGCCGCGTACAACGGCGAGTACA
TCGCCGACATCGCGCGCGACTACCTGAACGGCGAGACCGTCGCCGCGAGCGACGGCGAGCCGGTGACGGGCAAGCGCGAC
GTCGAGGATCTCGAGGCGATCCGCAAGTTCGCGGTCACGTACCTGCGCCGCGAGCAGGACATGGATCTGAAGGCGTTCGG
CGTGAAATTCGACCAGTACTACCTGGAATCGTCGCTCTACACGGAAGGCCGCGTCGAGAAAACCGTCGACGCGCTGATCG
CGGCCGGCATGACCTACGAGCAGGAAGGCGCGCTGTGGCTGCGCACGACCGACGAAGGCGACGACAAGGACCGCGTGATG
CGCAAGACGGACGGCACGTACACGTACTTCGTGCCGGATGTCGCGTACCACGTGACGAAGTGGGAGCGCGGCTTCACGAA
GGTCATCAACATTCAGGGCTCGGACCACCACGGCACGATCGCGCGCGTGCGCGCGGGCCTGCAGGGGCTGCACATCGGGA
TTCCGAAGGGCTACCCGGACTACGTGCTGCACAAGATGGTCACGGTGATGCGCGACGGCCAGGAAGTGAAGATCTCCAAG
CGCGCGGGCAGCTACGTGACGGTGCGCGACCTGATCGAATGGTCGGGCGGCGCGACGCCGGGCTCGGAAGGCTCGCCCGA
GCTGCTCGACGAGGCGACGATCACGCGCGGGCGCGACGCGGTGCGCTTCTTCCTGATTTCCCGCAAGGCGGACACCGAAT
TCGTGTTCGACATCGATCTCGCGCTGAAACAGAACGACGAAAACCCGGTCTACTACGTGCAGTACGCGCACGCGCGGATC
TGCTCGGTGATCAACGAATGGAAGTCGCGCTACGGCGCGACCGACGCGCTGCTGCCGGGCGCCGATCTCTCGCCGCTCGA
CAGCAAGCAGGCAATGGCGCTGATGCAAAAGCTCGCCGAATATCCGGACGTGCTCGCGCACGCGGCCGGCGAGCTCGCGC
CGCATGCGGTCGCGTTCTACCTGCGCGAGCTCGCGAGCGAGTTTCACTCGTTCTACAATGCGGAGCGCGTTCTCGTCGAC
GAACAAGCGCCGCGCACCGCGCGCGTCGCGCTCCTCGCGGCGACGCGCCAGGTGCTCGAAAACGGTCTCGCGATGCTCGG
CGTATCCGCGCCCAGCAAGATGTGA

Upstream 100 bases:

>100_bases
ATTAGCACCTGTTAAAATTCAGCGATCCCTGAAACGCGCGCCCTGCGGCGCGACGGCGCCCCGGCCACGCGGGCCGCCGC
CAACGATATCCTCGACCAGC

Downstream 100 bases:

>100_bases
ATCCGAGACCCTCGGCCAAGCGCCGCGGCGCAGCGCGTCGCGGCTGTTTCACGAAAACTTTCGCAGGTGACTCAAGCAAT
GGCAAAACCCCGCCGCACGT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAKPLGANPRQLAEQIVAALTAQ
PEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRAFGASERDHGKRVLLEFVSANPTGPLHVGHGRQAALGDALA
NVLASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRD
VEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYEQEGALWLRTTDEGDDKDRVM
RKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISK
RAGSYVTVRDLIEWSGGATPGSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARI
CSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFYLRELASEFHSFYNAERVLVD
EQAPRTARVALLAATRQVLENGLAMLGVSAPSKM

Sequences:

>Translated_594_residues
MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAKPLGANPRQLAEQIVAALTAQ
PEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRAFGASERDHGKRVLLEFVSANPTGPLHVGHGRQAALGDALA
NVLASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRD
VEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYEQEGALWLRTTDEGDDKDRVM
RKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISK
RAGSYVTVRDLIEWSGGATPGSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARI
CSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFYLRELASEFHSFYNAERVLVD
EQAPRTARVALLAATRQVLENGLAMLGVSAPSKM
>Mature_594_residues
MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAKPLGANPRQLAEQIVAALTAQ
PEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRAFGASERDHGKRVLLEFVSANPTGPLHVGHGRQAALGDALA
NVLASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRD
VEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYEQEGALWLRTTDEGDDKDRVM
RKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISK
RAGSYVTVRDLIEWSGGATPGSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARI
CSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFYLRELASEFHSFYNAERVLVD
EQAPRTARVALLAATRQVLENGLAMLGVSAPSKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=595, Percent_Identity=22.8571428571429, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1788184, Length=609, Percent_Identity=26.4367816091954, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71985061, Length=614, Percent_Identity=24.7557003257329, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71985068, Length=578, Percent_Identity=24.5674740484429, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320548, Length=616, Percent_Identity=26.6233766233766, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6321883, Length=580, Percent_Identity=24.8275862068966, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI18859963, Length=582, Percent_Identity=23.5395189003436, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571570, Length=493, Percent_Identity=21.9066937119675, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64521; Mature: 64521

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
PLGANPRQLAEQIVAALTAQPEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCC
FGASERDHGKRVLLEFVSANPTGPLHVGHGRQAALGDALANVLASQGYAVHREFYYNDAG
CCCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCC
VQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRD
CEECCEEEECHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCC
VEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYE
HHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEE
QEGALWLRTTDEGDDKDRVMRKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTI
CCCCEEEEECCCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHCCCEEEEEECCCCCCCHH
ARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISKRAGSYVTVRDLIEWSGGATP
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCCC
GSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARI
CCCCCHHHHHHHHHHCCCHHEEEEEEECCCCCEEEEEEEEEEECCCCCCEEEEEEHHHHH
CSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFY
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRELASEFHSFYNAERVLVDEQAPRTARVALLAATRQVLENGLAMLGVSAPSKM
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
PLGANPRQLAEQIVAALTAQPEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCC
FGASERDHGKRVLLEFVSANPTGPLHVGHGRQAALGDALANVLASQGYAVHREFYYNDAG
CCCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCC
VQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRD
CEECCEEEECHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCC
VEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYE
HHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEE
QEGALWLRTTDEGDDKDRVMRKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTI
CCCCEEEEECCCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHCCCEEEEEECCCCCCCHH
ARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISKRAGSYVTVRDLIEWSGGATP
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCCC
GSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARI
CCCCCHHHHHHHHHHCCCHHEEEEEEECCCCCEEEEEEEEEEECCCCCCEEEEEEHHHHH
CSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFY
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRELASEFHSFYNAERVLVDEQAPRTARVALLAATRQVLENGLAMLGVSAPSKM
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA