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The map label for this gene is ucpA [C]

Identifier: 53718020

GI number: 53718020

Start: 411739

End: 412518

Strand: Reverse

Name: ucpA [C]

Synonym: BPSL0380

Alternate gene names: 53718020

Gene position: 412518-411739 (Counterclockwise)

Preceding gene: 53718021

Following gene: 53718018

Centisome position: 10.12

GC content: 70.64

Gene sequence:

>780_bases
ATGAACGCCCCTGCCCCGCTCAAGGTCTTCATCACCGGCGCCTCCAGCGGGCTCGGCCTCGCGCTCGCCGCCGAATACGC
GCGGCACGGCGCGACGCTCGGCCTCGTCGCCCGGCGCGCCGACGCGCTCGCCGAGTTCGCGCCACGCTTTCCCAAGGCCT
CGATCTCGATCTACCCGGCCGACGTGCGCGACGCCGATGCGCTCGCGCTCGCCGCGTCGCGCTTCGTCGCCGCGCACGGG
TGCCCCGACGTCGTGATCGCGAACGCCGGCATCAGCAAGGGCGCGATCACGGGCGAAGGCGATCTGGCCGCGTTCCGCGA
GATCATGGACGTCAACTACTACGGGATGATCGCGACGTTCGAGCCGTTCATCGCGCCGATGACGGCCGCGCGGCGCGGCA
CGCTCGTCGGCATCGCGAGCGTGGCCGGCGTGCGCGGGCTGCCGGGCTCGGGCGCGTACAGCGCGTCGAAGGCGGCGGCG
ATCAAGTATCTCGAGGCGCTGAGGGTCGAGCTGCGGCCCGCGCAAGTCGCGGTCGTGACGATCGCGCCCGGCTACATCCG
CACGCCGTTGACCGAGCACAACCCGTATCCGATGCCGTTCCTGATGGATGCGGACCGCTTCGCGAAGCGCGCGGCGCTCG
CGATCTCGCAGAAAACCGCGTTTCGCGTGATTCCATGGCAGATGGGCATCGTCGCGAAGCTGCTGCACGTGATGCCGCGC
TGGCTGTACGATCGCCTGTTCGAGAAGGCGCCGCGCAAACCCAGGGCGAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
GGCCCGGCGTACACGAACAGCCTCGAAGGCACCGCGCAAGTGCTCGACTTCCTCGTCAAGCAAGTGCAGGACAAGAAGCT
GTAATCCCCATCGCGCCGGC

Downstream 100 bases:

>100_bases
GCGGGGCCGACGCCGGCGCGCGCCGCGATCCGCACGCACGACGGCGGCGAGCCGCCCTGCCGCCCTGCGCGACACCGTTC
ATCCATTCGCCCGTTCGTCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNAPAPLKVFITGASSGLGLALAAEYARHGATLGLVARRADALAEFAPRFPKASISIYPADVRDADALALAASRFVAAHG
CPDVVIANAGISKGAITGEGDLAAFREIMDVNYYGMIATFEPFIAPMTAARRGTLVGIASVAGVRGLPGSGAYSASKAAA
IKYLEALRVELRPAQVAVVTIAPGYIRTPLTEHNPYPMPFLMDADRFAKRAALAISQKTAFRVIPWQMGIVAKLLHVMPR
WLYDRLFEKAPRKPRAKAG

Sequences:

>Translated_259_residues
MNAPAPLKVFITGASSGLGLALAAEYARHGATLGLVARRADALAEFAPRFPKASISIYPADVRDADALALAASRFVAAHG
CPDVVIANAGISKGAITGEGDLAAFREIMDVNYYGMIATFEPFIAPMTAARRGTLVGIASVAGVRGLPGSGAYSASKAAA
IKYLEALRVELRPAQVAVVTIAPGYIRTPLTEHNPYPMPFLMDADRFAKRAALAISQKTAFRVIPWQMGIVAKLLHVMPR
WLYDRLFEKAPRKPRAKAG
>Mature_259_residues
MNAPAPLKVFITGASSGLGLALAAEYARHGATLGLVARRADALAEFAPRFPKASISIYPADVRDADALALAASRFVAAHG
CPDVVIANAGISKGAITGEGDLAAFREIMDVNYYGMIATFEPFIAPMTAARRGTLVGIASVAGVRGLPGSGAYSASKAAA
IKYLEALRVELRPAQVAVVTIAPGYIRTPLTEHNPYPMPFLMDADRFAKRAALAISQKTAFRVIPWQMGIVAKLLHVMPR
WLYDRLFEKAPRKPRAKAG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=31.9371727748691, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=28.125, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI157739938, Length=196, Percent_Identity=29.0816326530612, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI40807363, Length=255, Percent_Identity=28.6274509803922, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503817, Length=205, Percent_Identity=30.7317073170732, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI223718074, Length=198, Percent_Identity=32.8282828282828, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI7657478, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4758504, Length=205, Percent_Identity=33.1707317073171, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=31.7948717948718, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786701, Length=186, Percent_Identity=30.1075268817204, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=24.5810055865922, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=26.3736263736264, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=243, Percent_Identity=26.7489711934156, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17570069, Length=186, Percent_Identity=33.8709677419355, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71997402, Length=186, Percent_Identity=31.7204301075269, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=227, Percent_Identity=27.7533039647577, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17507613, Length=199, Percent_Identity=28.1407035175879, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=199, Percent_Identity=28.1407035175879, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=203, Percent_Identity=28.0788177339901, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=189, Percent_Identity=28.042328042328, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=29.4736842105263, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=202, Percent_Identity=28.7128712871287, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=27.9569892473118, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=190, Percent_Identity=32.1052631578947, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=29.8429319371728, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=32.8125, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=231, Percent_Identity=31.1688311688312, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357041, Length=185, Percent_Identity=31.3513513513514, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281364892, Length=212, Percent_Identity=29.2452830188679, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644339, Length=210, Percent_Identity=30.4761904761905, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=205, Percent_Identity=28.780487804878, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24649181, Length=252, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355631, Length=204, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24580925, Length=194, Percent_Identity=29.8969072164948, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641388, Length=195, Percent_Identity=32.8205128205128, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007236, Length=208, Percent_Identity=27.4038461538462, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=29.2929292929293, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24581726, Length=203, Percent_Identity=26.1083743842365, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27503; Mature: 27503

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPAPLKVFITGASSGLGLALAAEYARHGATLGLVARRADALAEFAPRFPKASISIYPA
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
DVRDADALALAASRFVAAHGCPDVVIANAGISKGAITGEGDLAAFREIMDVNYYGMIATF
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEH
EPFIAPMTAARRGTLVGIASVAGVRGLPGSGAYSASKAAAIKYLEALRVELRPAQVAVVT
HHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
IAPGYIRTPLTEHNPYPMPFLMDADRFAKRAALAISQKTAFRVIPWQMGIVAKLLHVMPR
ECCCHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHH
WLYDRLFEKAPRKPRAKAG
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNAPAPLKVFITGASSGLGLALAAEYARHGATLGLVARRADALAEFAPRFPKASISIYPA
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
DVRDADALALAASRFVAAHGCPDVVIANAGISKGAITGEGDLAAFREIMDVNYYGMIATF
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEH
EPFIAPMTAARRGTLVGIASVAGVRGLPGSGAYSASKAAAIKYLEALRVELRPAQVAVVT
HHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
IAPGYIRTPLTEHNPYPMPFLMDADRFAKRAALAISQKTAFRVIPWQMGIVAKLLHVMPR
ECCCHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHH
WLYDRLFEKAPRKPRAKAG
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]