Click here to switch to the map view.

The map label for this gene is rhtC [H]

Identifier: 53717883

GI number: 53717883

Start: 252590

End: 253243

Strand: Reverse

Name: rhtC [H]

Synonym: BPSL0242

Alternate gene names: 53717883

Gene position: 253243-252590 (Counterclockwise)

Preceding gene: 53717884

Following gene: 53717882

Centisome position: 6.22

GC content: 72.78

Gene sequence:

>654_bases
ATGAACCTGCTGCCGATCCTGCTGCAAATCGCCGCCGTCTACCTCCTCGCGCTCGTCACGCCGGGCCCGAACATCTTCAT
GATCTCGCAGCTGTCGCTGTCGGGCCGTCGCGGCCTCGGCGCCGTGTCGGCGCTCGGCGTCGGCACCGCGTCGCTCACGT
GGGCGACGCTCGCGATGCTCGGCGTCGCGGCCGTGCTGCATCAGCTCGCCTGGCTGTACGAGGCGATCCGGATCGGCGGC
GCGGTCTATCTCGCGTATTTCGGCATCAAGCTGCTGCGCGCGAGCGCGCAGCGCGACCCCGCGCCGGCGGCCGGCCTCGC
GGACGACGCGGGCGCCCTCCCGAGCCCGCCCGCGACGCGCGATTACCTGCGCGCGTACCGCACGGGCCTCTTCACGTGCC
TGACGAACCCGAAATCGTGCGTGTTCTGGACGAGCGTGTTCGCGGCGATGATGCCCGCGCACGTGCCGCTGTGGTTCAGC
GGCGCGACGCTGCTGACGATCGGCGCGATGTCGGGCGGCTGGTATTGCGGCGTCGCGTACCTGTTCGCGAATCCGCGCGC
GCAGCGCGGCTACCGGCGCGTGCGGCGCCCGCTCGACGCGCTGTGCGGCGCGGCGCTCGTCGGCCTCGGCGCGAAGCTCG
CGGCCGACCGGTAA

Upstream 100 bases:

>100_bases
CGTACGTCGCGCGGCTGCGGCTCGACCCGGCGTGAGCACGGCGGCGCGCGGCGCGCTACATTAACGGCTTGGCTTGCTCC
TGCGTCGACCCCGCGCCACC

Downstream 100 bases:

>100_bases
CGGCCGCCGGGCGGCAATTCGTTGCGCCAAATCCGCGCGCCGCTCGGGGGCCGAGCCCGCGCGTGCCTCAAGCAGGGTAA
AATAGCAAGTTCCTCAATCG

Product: LysE type translocator

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNLLPILLQIAAVYLLALVTPGPNIFMISQLSLSGRRGLGAVSALGVGTASLTWATLAMLGVAAVLHQLAWLYEAIRIGG
AVYLAYFGIKLLRASAQRDPAPAAGLADDAGALPSPPATRDYLRAYRTGLFTCLTNPKSCVFWTSVFAAMMPAHVPLWFS
GATLLTIGAMSGGWYCGVAYLFANPRAQRGYRRVRRPLDALCGAALVGLGAKLAADR

Sequences:

>Translated_217_residues
MNLLPILLQIAAVYLLALVTPGPNIFMISQLSLSGRRGLGAVSALGVGTASLTWATLAMLGVAAVLHQLAWLYEAIRIGG
AVYLAYFGIKLLRASAQRDPAPAAGLADDAGALPSPPATRDYLRAYRTGLFTCLTNPKSCVFWTSVFAAMMPAHVPLWFS
GATLLTIGAMSGGWYCGVAYLFANPRAQRGYRRVRRPLDALCGAALVGLGAKLAADR
>Mature_217_residues
MNLLPILLQIAAVYLLALVTPGPNIFMISQLSLSGRRGLGAVSALGVGTASLTWATLAMLGVAAVLHQLAWLYEAIRIGG
AVYLAYFGIKLLRASAQRDPAPAAGLADDAGALPSPPATRDYLRAYRTGLFTCLTNPKSCVFWTSVFAAMMPAHVPLWFS
GATLLTIGAMSGGWYCGVAYLFANPRAQRGYRRVRRPLDALCGAALVGLGAKLAADR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=219, Percent_Identity=31.0502283105023, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786522, Length=194, Percent_Identity=26.2886597938144, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788099, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22896; Mature: 22896

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLPILLQIAAVYLLALVTPGPNIFMISQLSLSGRRGLGAVSALGVGTASLTWATLAML
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHH
GVAAVLHQLAWLYEAIRIGGAVYLAYFGIKLLRASAQRDPAPAAGLADDAGALPSPPATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
DYLRAYRTGLFTCLTNPKSCVFWTSVFAAMMPAHVPLWFSGATLLTIGAMSGGWYCGVAY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHEEEECCCCCHHHHHHH
LFANPRAQRGYRRVRRPLDALCGAALVGLGAKLAADR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MNLLPILLQIAAVYLLALVTPGPNIFMISQLSLSGRRGLGAVSALGVGTASLTWATLAML
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHH
GVAAVLHQLAWLYEAIRIGGAVYLAYFGIKLLRASAQRDPAPAAGLADDAGALPSPPATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
DYLRAYRTGLFTCLTNPKSCVFWTSVFAAMMPAHVPLWFSGATLLTIGAMSGGWYCGVAY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHEEEECCCCCHHHHHHH
LFANPRAQRGYRRVRRPLDALCGAALVGLGAKLAADR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]