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The map label for this gene is oxaA [H]

Identifier: 52843195

GI number: 52843195

Start: 3395275

End: 3396945

Strand: Reverse

Name: oxaA [H]

Synonym: lpg3002

Alternate gene names: 52843195

Gene position: 3396945-3395275 (Counterclockwise)

Preceding gene: 52843196

Following gene: 52843194

Centisome position: 99.98

GC content: 36.68

Gene sequence:

>1671_bases
ATGGATATACGACGTATAGTTTTATATATGGCGCTTGCGCTTATTGGTTTATCACTTTGGAACGCTTGGCAAATTGATTA
TCCAGCCAAACAACCAGTTGAAGAGAAGACAGCAAGCCAATTAACATCAGATGGGCATTTGTTACCACAAATAATTCCTT
CTAATGCAGAGCAACCCGTAACTTTGAAAGCAGAGGAAAAAGCAAGCAGCGGTAAACAATTGATTCAGGTTAAAACAGAT
GTTTTGGATGTCGACATTGATTTAAAAAATGGAGATATTGTTAAAGGTTTATTGCTTGATTATCCACTAAGTGTTGAAGA
TAAAAATAAACCATTCCCTCTCTTGCAAAATCAGGCCAGCCAGAGATATGTAGCGAACAGTAGCCTTTTTGTTTTAGATG
GCCAGACACCACAATCATTGGATTTTGATTTTACATCAGAAAAAGAATATTACGAATTGAAACCTGATCAAAACCAGCTG
ATAGTCACTCTAAATGGCAAAAGCGAAGACGGTTTGGATGTGAAAAAAGAATTTGTTTTTACAAAGGGAAGTTATTTAAT
CGAAGTCAATTACAAGATAGCCAATACCGGTAATTCGTTATGGAAAGGGTATTTTAATACCCAGTTATTGCGCAGTTCTC
CCAAAGAAGACAAATCGAGTATTTTTCATATTGGCTCGTATACAGGTGCTTCCTTTTCAAATCCTGGAAAAAATCGTTAC
CAAAAAGTTAGTTTCAGTGACATGAGCAAATCTAACCTGGATGTGGATGCAAAAGGTGGTTGGATTGCTATGCAACAACA
CTATTTTTTGAGTGCTTGGGTTCCCAATGCGGATAGTGAAAACAAGTTTTATACATTAGCTACGGATAAAGATTATACTA
TTGGAGCAGTAAGCCAGCCTATTACGGTCAAACCAAAAGAAGATAAAATTGTAGGATCCAAATTATACATAGGACCAGAA
ATTACCAGTGTTTTAAAAGGCATATCCCCATCTCTGGATTTAACGGTGGACTATGGCATTTTGTGGTTCTTGTCTTCGTT
ATTATTTTCTTTAATGAAAGCAATTTATACTGTTGTTGGGAATTGGGGCTGGTCAATTGTTCTTGTGACTGTCCTAATTA
AATTGGCATTTTATCGATTATCAGCTACAAGCTATAAATCCATGGCTAGTATGCGGAAGTTGCAGCCTAAGTTGCAAGCT
TTGCGTGAGCGATATGGTGATGATAAAGCTAAAATAAGCCAAGCTACCATGGAACTTTATAAGCAAGAAAAAGTAAATCC
TTTAGGCGGCTGTTTACCTATATTAATTCAAATTCCAGTTTTTATAGCGCTCTATTGGGTTTTACTGGAAAGTGTTGAGT
TAAGACAAGCTCCATTTATATTTTGGATAAATGATTTGGCTTCAGCAGATCCTTACCATGTTCTTCCATTGATCATGGGA
GCAACCATGTTGATTCAGCAAAAGCTCAATCCAGCACCAGCTGATCCAATGCAAGCTAAGGTAATGATGTTTTTACCCAT
ATTATTTACCGGACTGTTCTGGAATTTTCCTTCTGGTCTGGTTTTGTACTGGATTGTGAATAATACTTTATCAATATTAC
AGCAATGGTACATCACCAGAAAATACTCAGATGAAAAGCCAGCTAAAAAGGTTGTTGCCACAGCAAAATAA

Upstream 100 bases:

>100_bases
AGGTTTATTGATGGCACTTAACAGATTGTCTCGTTGCCATCCATGGTCAAAAGGTGGCTATGATCCTTTATTTCCTAACG
ATAAGAATTGAGAATATTTA

Downstream 100 bases:

>100_bases
ATGTCAATAGATACCATTGTTGCTATCGCTACCCCGCCAGGACGAGGCGGGGTAGGAATCGTCAGAATATCAGGTCCAAA
TGCTTATGCTATAGCCCTTT

Product: inner membrane protein, 60 kDa

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MDIRRIVLYMALALIGLSLWNAWQIDYPAKQPVEEKTASQLTSDGHLLPQIIPSNAEQPVTLKAEEKASSGKQLIQVKTD
VLDVDIDLKNGDIVKGLLLDYPLSVEDKNKPFPLLQNQASQRYVANSSLFVLDGQTPQSLDFDFTSEKEYYELKPDQNQL
IVTLNGKSEDGLDVKKEFVFTKGSYLIEVNYKIANTGNSLWKGYFNTQLLRSSPKEDKSSIFHIGSYTGASFSNPGKNRY
QKVSFSDMSKSNLDVDAKGGWIAMQQHYFLSAWVPNADSENKFYTLATDKDYTIGAVSQPITVKPKEDKIVGSKLYIGPE
ITSVLKGISPSLDLTVDYGILWFLSSLLFSLMKAIYTVVGNWGWSIVLVTVLIKLAFYRLSATSYKSMASMRKLQPKLQA
LRERYGDDKAKISQATMELYKQEKVNPLGGCLPILIQIPVFIALYWVLLESVELRQAPFIFWINDLASADPYHVLPLIMG
ATMLIQQKLNPAPADPMQAKVMMFLPILFTGLFWNFPSGLVLYWIVNNTLSILQQWYITRKYSDEKPAKKVVATAK

Sequences:

>Translated_556_residues
MDIRRIVLYMALALIGLSLWNAWQIDYPAKQPVEEKTASQLTSDGHLLPQIIPSNAEQPVTLKAEEKASSGKQLIQVKTD
VLDVDIDLKNGDIVKGLLLDYPLSVEDKNKPFPLLQNQASQRYVANSSLFVLDGQTPQSLDFDFTSEKEYYELKPDQNQL
IVTLNGKSEDGLDVKKEFVFTKGSYLIEVNYKIANTGNSLWKGYFNTQLLRSSPKEDKSSIFHIGSYTGASFSNPGKNRY
QKVSFSDMSKSNLDVDAKGGWIAMQQHYFLSAWVPNADSENKFYTLATDKDYTIGAVSQPITVKPKEDKIVGSKLYIGPE
ITSVLKGISPSLDLTVDYGILWFLSSLLFSLMKAIYTVVGNWGWSIVLVTVLIKLAFYRLSATSYKSMASMRKLQPKLQA
LRERYGDDKAKISQATMELYKQEKVNPLGGCLPILIQIPVFIALYWVLLESVELRQAPFIFWINDLASADPYHVLPLIMG
ATMLIQQKLNPAPADPMQAKVMMFLPILFTGLFWNFPSGLVLYWIVNNTLSILQQWYITRKYSDEKPAKKVVATAK
>Mature_556_residues
MDIRRIVLYMALALIGLSLWNAWQIDYPAKQPVEEKTASQLTSDGHLLPQIIPSNAEQPVTLKAEEKASSGKQLIQVKTD
VLDVDIDLKNGDIVKGLLLDYPLSVEDKNKPFPLLQNQASQRYVANSSLFVLDGQTPQSLDFDFTSEKEYYELKPDQNQL
IVTLNGKSEDGLDVKKEFVFTKGSYLIEVNYKIANTGNSLWKGYFNTQLLRSSPKEDKSSIFHIGSYTGASFSNPGKNRY
QKVSFSDMSKSNLDVDAKGGWIAMQQHYFLSAWVPNADSENKFYTLATDKDYTIGAVSQPITVKPKEDKIVGSKLYIGPE
ITSVLKGISPSLDLTVDYGILWFLSSLLFSLMKAIYTVVGNWGWSIVLVTVLIKLAFYRLSATSYKSMASMRKLQPKLQA
LRERYGDDKAKISQATMELYKQEKVNPLGGCLPILIQIPVFIALYWVLLESVELRQAPFIFWINDLASADPYHVLPLIMG
ATMLIQQKLNPAPADPMQAKVMMFLPILFTGLFWNFPSGLVLYWIVNNTLSILQQWYITRKYSDEKPAKKVVATAK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=552, Percent_Identity=42.7536231884058, Blast_Score=424, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24662345, Length=192, Percent_Identity=27.6041666666667, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356443, Length=192, Percent_Identity=27.6041666666667, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 62636; Mature: 62636

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRRIVLYMALALIGLSLWNAWQIDYPAKQPVEEKTASQLTSDGHLLPQIIPSNAEQPV
CCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCE
TLKAEEKASSGKQLIQVKTDVLDVDIDLKNGDIVKGLLLDYPLSVEDKNKPFPLLQNQAS
EEEEHHCCCCCCEEEEEEEEEEEEEEECCCCCEEEHHHHCCCCCCCCCCCCCCHHHCCCH
QRYVANSSLFVLDGQTPQSLDFDFTSEKEYYELKPDQNQLIVTLNGKSEDGLDVKKEFVF
HHEEECCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHEEE
TKGSYLIEVNYKIANTGNSLWKGYFNTQLLRSSPKEDKSSIFHIGSYTGASFSNPGKNRY
ECCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCE
QKVSFSDMSKSNLDVDAKGGWIAMQQHYFLSAWVPNADSENKFYTLATDKDYTIGAVSQP
EECCCCCCCCCCCCEECCCCEEEEEECEEEEEECCCCCCCCCEEEEECCCCCEEECCCCC
ITVKPKEDKIVGSKLYIGPEITSVLKGISPSLDLTVDYGILWFLSSLLFSLMKAIYTVVG
EEECCCCCCEECCEEEECHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
NWGWSIVLVTVLIKLAFYRLSATSYKSMASMRKLQPKLQALRERYGDDKAKISQATMELY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KQEKVNPLGGCLPILIQIPVFIALYWVLLESVELRQAPFIFWINDLASADPYHVLPLIMG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCHHHHHHHHH
ATMLIQQKLNPAPADPMQAKVMMFLPILFTGLFWNFPSGLVLYWIVNNTLSILQQWYITR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
KYSDEKPAKKVVATAK
CCCCCCHHHHHHCCCC
>Mature Secondary Structure
MDIRRIVLYMALALIGLSLWNAWQIDYPAKQPVEEKTASQLTSDGHLLPQIIPSNAEQPV
CCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCE
TLKAEEKASSGKQLIQVKTDVLDVDIDLKNGDIVKGLLLDYPLSVEDKNKPFPLLQNQAS
EEEEHHCCCCCCEEEEEEEEEEEEEEECCCCCEEEHHHHCCCCCCCCCCCCCCHHHCCCH
QRYVANSSLFVLDGQTPQSLDFDFTSEKEYYELKPDQNQLIVTLNGKSEDGLDVKKEFVF
HHEEECCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHEEE
TKGSYLIEVNYKIANTGNSLWKGYFNTQLLRSSPKEDKSSIFHIGSYTGASFSNPGKNRY
ECCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCE
QKVSFSDMSKSNLDVDAKGGWIAMQQHYFLSAWVPNADSENKFYTLATDKDYTIGAVSQP
EECCCCCCCCCCCCEECCCCEEEEEECEEEEEECCCCCCCCCEEEEECCCCCEEECCCCC
ITVKPKEDKIVGSKLYIGPEITSVLKGISPSLDLTVDYGILWFLSSLLFSLMKAIYTVVG
EEECCCCCCEECCEEEECHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
NWGWSIVLVTVLIKLAFYRLSATSYKSMASMRKLQPKLQALRERYGDDKAKISQATMELY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KQEKVNPLGGCLPILIQIPVFIALYWVLLESVELRQAPFIFWINDLASADPYHVLPLIMG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCHHHHHHHHH
ATMLIQQKLNPAPADPMQAKVMMFLPILFTGLFWNFPSGLVLYWIVNNTLSILQQWYITR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
KYSDEKPAKKVVATAK
CCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA