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The map label for this gene is waaM

Identifier: 52843134

GI number: 52843134

Start: 3325915

End: 3326751

Strand: Reverse

Name: waaM

Synonym: lpg2940

Alternate gene names: 52843134

Gene position: 3326751-3325915 (Counterclockwise)

Preceding gene: 52843135

Following gene: 52843133

Centisome position: 97.91

GC content: 37.28

Gene sequence:

>837_bases
ATGACTAACCACTATTTGTCCAAACTCCGAGTGACTTTTGCAGGGCTTCTTTTTTACTGGATTTTGCCTCTTCGTAAGCA
AATTGTATTGAGTAATATCGACCTCGTTTTTAAAAATTCAGCGACTCCTGCTGAAAAAACAAGATTAGCCAAAGCGTTTT
ACTCTCATGTCGCATCTAATTTAAAAGAACTCATTTGGATGGGTTGGGCAAGTTCTAAAGGATTGACTAATAAGATAGAG
ATTCATGGTTTAGAGCATTTGGAAAGCGCTGTGAGTCAGAATAAAGGGGTTTTTCTGCTCACTGGTCATTTAGGTAATTG
GGAATTAGCTTATACTTTAGGTTTTTCTCGCCTGATGCCTCAATATGGGCAATTTAATATCATCAGACGACCCATTAAAA
TAAAATGGCTGGAATCAATATTGTTTAATAGGATGATACGCTATGGATTAACAATTACCAGCAGCATTAGTGCGCCAAAA
AAAATAAATCAAGCCTTAAGAAACAAGGAATTAGTACTTTTTACACTCGATCAGCATGCGAAATTGGAAAATAAATCAGG
AATCGCTGTCGAGTTTTTTGGCCTTCATGCTGGGACATACCGAAGTTTGGCCTTTTTTGCCCATAAACATCAAACACCAG
TAGTCCCCGTATCCGGCTATAGGCTACACAACGGCAAGCACGTTATTAAATTTCATCCAGAAATAGAATGGGAATTTCAT
GTCGATAAAGAACAAGCTATCTACAGAAATACTCTTCGCTATAATCAAATGCTTGAAAAATTAATTTTGGAATATCCGGA
GCAATGGTGGTGGGTTCATAGACGATGGAAATTATAA

Upstream 100 bases:

>100_bases
ACTCTTGTCGAAAACACTCAGCTTTATAATAAAAGATTGGAAGAGATGTTATTGCCTTACCCTGAGCAATGGTTATGGTC
ATACAAACGTTGGAAAAATA

Downstream 100 bases:

>100_bases
GCTAAAAATGTAAAGAAACCCAAATATTATTTTACAAAATGAAAATGAATATTTTTCAAATGTTGATGTCATCAAAAAAT
CATCTGGTTTATTTAGGATG

Product: lipid A lauroyl acyltransferase

Products: KDO2-(lauroyl)-lipid IVA [C]

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Lipd A Biosynthesis Related Exported Protein; Bacterial Lipid A Biosynthesis Acyltransferase; Lipid A Lauroyl Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily; Lauroyl Acyltransferase; Lipid A Biosynthesis Lauroyl; Dodecanoyltransferase LpxL

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTNHYLSKLRVTFAGLLFYWILPLRKQIVLSNIDLVFKNSATPAEKTRLAKAFYSHVASNLKELIWMGWASSKGLTNKIE
IHGLEHLESAVSQNKGVFLLTGHLGNWELAYTLGFSRLMPQYGQFNIIRRPIKIKWLESILFNRMIRYGLTITSSISAPK
KINQALRNKELVLFTLDQHAKLENKSGIAVEFFGLHAGTYRSLAFFAHKHQTPVVPVSGYRLHNGKHVIKFHPEIEWEFH
VDKEQAIYRNTLRYNQMLEKLILEYPEQWWWVHRRWKL

Sequences:

>Translated_278_residues
MTNHYLSKLRVTFAGLLFYWILPLRKQIVLSNIDLVFKNSATPAEKTRLAKAFYSHVASNLKELIWMGWASSKGLTNKIE
IHGLEHLESAVSQNKGVFLLTGHLGNWELAYTLGFSRLMPQYGQFNIIRRPIKIKWLESILFNRMIRYGLTITSSISAPK
KINQALRNKELVLFTLDQHAKLENKSGIAVEFFGLHAGTYRSLAFFAHKHQTPVVPVSGYRLHNGKHVIKFHPEIEWEFH
VDKEQAIYRNTLRYNQMLEKLILEYPEQWWWVHRRWKL
>Mature_277_residues
TNHYLSKLRVTFAGLLFYWILPLRKQIVLSNIDLVFKNSATPAEKTRLAKAFYSHVASNLKELIWMGWASSKGLTNKIEI
HGLEHLESAVSQNKGVFLLTGHLGNWELAYTLGFSRLMPQYGQFNIIRRPIKIKWLESILFNRMIRYGLTITSSISAPKK
INQALRNKELVLFTLDQHAKLENKSGIAVEFFGLHAGTYRSLAFFAHKHQTPVVPVSGYRLHNGKHVIKFHPEIEWEFHV
DKEQAIYRNTLRYNQMLEKLILEYPEQWWWVHRRWKL

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 32612; Mature: 32481

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHYLSKLRVTFAGLLFYWILPLRKQIVLSNIDLVFKNSATPAEKTRLAKAFYSHVASN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHH
LKELIWMGWASSKGLTNKIEIHGLEHLESAVSQNKGVFLLTGHLGNWELAYTLGFSRLMP
HHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECHHHHCC
QYGQFNIIRRPIKIKWLESILFNRMIRYGLTITSSISAPKKINQALRNKELVLFTLDQHA
CCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHCCCCEEEEECCCCC
KLENKSGIAVEFFGLHAGTYRSLAFFAHKHQTPVVPVSGYRLHNGKHVIKFHPEIEWEFH
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECCCEEEECCCEEEEECCCEEEEEE
VDKEQAIYRNTLRYNQMLEKLILEYPEQWWWVHRRWKL
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHEEECC
>Mature Secondary Structure 
TNHYLSKLRVTFAGLLFYWILPLRKQIVLSNIDLVFKNSATPAEKTRLAKAFYSHVASN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHH
LKELIWMGWASSKGLTNKIEIHGLEHLESAVSQNKGVFLLTGHLGNWELAYTLGFSRLMP
HHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECHHHHCC
QYGQFNIIRRPIKIKWLESILFNRMIRYGLTITSSISAPKKINQALRNKELVLFTLDQHA
CCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHCCCCEEEEECCCCC
KLENKSGIAVEFFGLHAGTYRSLAFFAHKHQTPVVPVSGYRLHNGKHVIKFHPEIEWEFH
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECCCEEEECCCEEEEECCCEEEEEE
VDKEQAIYRNTLRYNQMLEKLILEYPEQWWWVHRRWKL
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; lauroyl-ACP [C]

Specific reaction: KDO2-lipid IVA + lauroyl-ACP = KDO2-(lauroyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA