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The map label for this gene is queC [H]

Identifier: 52843081

GI number: 52843081

Start: 3266369

End: 3267070

Strand: Reverse

Name: queC [H]

Synonym: lpg2886

Alternate gene names: 52843081

Gene position: 3267070-3266369 (Counterclockwise)

Preceding gene: 52843088

Following gene: 52843080

Centisome position: 96.15

GC content: 43.16

Gene sequence:

>702_bases
TTGAGGTTTTGCATTATGAAAAAAGCTGTGGTCTTGCTTTCTGGCGGTTTGGATTCAACGACTTGTCTCGCGTTGGCTAA
ATCTCAGGGGTTTGCTTGTTATGCATTAAGCTTTTCTTACGGCCAGAGGCATTCCGCAGAACTGTGTGCCGCAACTCGAA
TTGCGAAACATATGGGTGCAGCTGATCATAAAATAGTCACCCTGGATATCGCTTTATTTGGTGGCTCCGCTTTGACTGAT
GCATCTATTGAGGTCCCCGAATTCAAGGAAAGCCCGGAAATACCAGTCACCTATGTCCCAGCCCGTAATACTATTTTTTT
GGCTATGGCTTTGGGTTATGCTGAATCAATTGGTGCCAGAGATATTTTTATTGGTGCCAGTTCTGTTGATTATTCCCATT
ATCCTGATTGTCGCCCGGAGTTTATTGAATCTTTCCAATCTTTGGCAAACTTGGCAACGAAAGCAGGAATTGAAGGCGAT
CGCTTTACTATCAATGCTCCTCTGCAATATCTGAGCAAAGTGCAGACTATTCAATTAGGTACTGAACTTGGTGTTGATTA
CGGATTAACGGTTTCCTGCTATCAAGCGAATGAAGCAGGTGAAGCTTGCGGACAGTGTGATAGCTGTACTTTTAGAAAGC
GGGGTTTTAAGAGTGCTGGAGTAGATGATCCCACTCGATATCAAAAATGTGTTCATATTTAA

Upstream 100 bases:

>100_bases
ATTATTGGATATAGAGGTGTCGTCATCACATTCCATATTGTGGCATAATTGACCTGCATTTTAGCAGGAATTTTTAAGAG
CAAGCAATTGTTCCAATTTT

Downstream 100 bases:

>100_bases
CCCACACAGTTAAATTAATGATATAATCCCTGAAATTTTGGTTTGGAGTTTTTTATGTGGGATAAAATCAAAGAATGGTA
TAAAAATAACAAGAGCTATT

Product: ExsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRFCIMKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMGAADHKIVTLDIALFGGSALTD
ASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGD
RFTINAPLQYLSKVQTIQLGTELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVDDPTRYQKCVHI

Sequences:

>Translated_233_residues
MRFCIMKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMGAADHKIVTLDIALFGGSALTD
ASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGD
RFTINAPLQYLSKVQTIQLGTELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVDDPTRYQKCVHI
>Mature_233_residues
MRFCIMKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMGAADHKIVTLDIALFGGSALTD
ASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGD
RFTINAPLQYLSKVQTIQLGTELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVDDPTRYQKCVHI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=38.3259911894273, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25128; Mature: 25128

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFCIMKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMGA
CCCHHHHHEEEEEECCCCCHHHEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCC
ADHKIVTLDIALFGGSALTDASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGAR
CCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHHHHHCCCC
DIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTINAPLQYLSKVQTIQLG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHEEEH
TELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVDDPTRYQKCVHI
HHHCCCCCCEEEEEECCCHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MRFCIMKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMGA
CCCHHHHHEEEEEECCCCCHHHEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCC
ADHKIVTLDIALFGGSALTDASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGAR
CCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHHHHHCCCC
DIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTINAPLQYLSKVQTIQLG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHEEEH
TELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVDDPTRYQKCVHI
HHHCCCCCCEEEEEECCCHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA