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The map label for this gene is corA

Identifier: 52843073

GI number: 52843073

Start: 3257398

End: 3258462

Strand: Direct

Name: corA

Synonym: lpg2878

Alternate gene names: 52843073

Gene position: 3257398-3258462 (Clockwise)

Preceding gene: 52843071

Following gene: 52843078

Centisome position: 95.87

GC content: 35.31

Gene sequence:

>1065_bases
ATGAATACTCATAAAACAAAGGCTTCAGCAAAAGCGGGACTCTTACCGGGGACTGCCGTATATATAGGCGAACACCCACC
GCAACCAACTCAAGTAACGATACATATTTATGACAAAAAAAATTATAAGCGTTTAGATTCCTTCGATACCCGACAAGTGA
AAGAGGCCTATGAAGCTGGACATAATATTTGGATAGATATTTCAGGTCTTGCAGACATCGAGAAAATTACTAAAATTTGC
TCAGAATACAACATACACCCCTTGGTTATCGAGGATTTGCTTAATACCAGACAAAGACCCAAACTGGATATTGTAGACGA
TTATATTTTTGTTGTTTTTAAATTATTACAATCCCCTCCCGATCACTTATCTTACAATACAGAACAGTTCTGTTTAATCA
TCAAGCAAAAACTTTTACTCACATTCAGAGAATCTGAAAAATATAATTTATCTTCCATTTATCAACGCCTTAATGGAGAG
CACTCGTTAACCAGAGAATATGGAAGTGATTATTTGACCTATCTGATCATGGACTATATTGTTGATGATTATTTCAACTT
TGTCGAAACTTCAGCCCAACTGCTTGAAACCTTGGAAGATCAATTAATTAATAAACCAGAAACGATTAGGTTACAAGCGT
TATACACCATCAAAAGAAGAACCATTACCCTCAGAAAAATCATTCCTCCTTTGAGAGATATTGTCCATTTGTTGCTTACA
GACGATGGGGGGTTAATCAATAAAAAGTATAATCTTTACTTCCGGGACTTATATGATCATTGCATTCGCCTGGTAGAATC
GATCGATTTGCATAGAGAAATGTCGGCAAGTATGCTAGACATATACCTGTCTACTATAAATAATCGCATGAATGAATCCA
TGAAAATTCTGACCTTGTTTGCCAGTATTTTTATTCCTTTAAGTTTTATTGCCGGGGTTTATGGAATGAATTTTAAATTT
ATGCCTGAGCTGGATTGGCGATACGGTTACCCTATGATTCTGGTTACCATGGTACTTCTGGCAATACTCATGCTGTATTT
TTTTAAACGAAAAAAATTATTTTAA

Upstream 100 bases:

>100_bases
AGCCCTTTGCATAGCAAGATAAACGAGAGTCGTCAACTGTCGACTTAAACGATGACTAAATGATAAGTTAATAAGAAAAT
AAATAAACTGAGATAACTTC

Downstream 100 bases:

>100_bases
GTGGCGGAAAGCGCCCCATTTACAACCTGCATAATATCATCGATAGAACTGGGTAGGGTCTTTACCGGGCAACACACTTC
TGTTGCCCTCTTGTCAGAAA

Product: cobalt/magnesium uptake transporter

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNTHKTKASAKAGLLPGTAVYIGEHPPQPTQVTIHIYDKKNYKRLDSFDTRQVKEAYEAGHNIWIDISGLADIEKITKIC
SEYNIHPLVIEDLLNTRQRPKLDIVDDYIFVVFKLLQSPPDHLSYNTEQFCLIIKQKLLLTFRESEKYNLSSIYQRLNGE
HSLTREYGSDYLTYLIMDYIVDDYFNFVETSAQLLETLEDQLINKPETIRLQALYTIKRRTITLRKIIPPLRDIVHLLLT
DDGGLINKKYNLYFRDLYDHCIRLVESIDLHREMSASMLDIYLSTINNRMNESMKILTLFASIFIPLSFIAGVYGMNFKF
MPELDWRYGYPMILVTMVLLAILMLYFFKRKKLF

Sequences:

>Translated_354_residues
MNTHKTKASAKAGLLPGTAVYIGEHPPQPTQVTIHIYDKKNYKRLDSFDTRQVKEAYEAGHNIWIDISGLADIEKITKIC
SEYNIHPLVIEDLLNTRQRPKLDIVDDYIFVVFKLLQSPPDHLSYNTEQFCLIIKQKLLLTFRESEKYNLSSIYQRLNGE
HSLTREYGSDYLTYLIMDYIVDDYFNFVETSAQLLETLEDQLINKPETIRLQALYTIKRRTITLRKIIPPLRDIVHLLLT
DDGGLINKKYNLYFRDLYDHCIRLVESIDLHREMSASMLDIYLSTINNRMNESMKILTLFASIFIPLSFIAGVYGMNFKF
MPELDWRYGYPMILVTMVLLAILMLYFFKRKKLF
>Mature_354_residues
MNTHKTKASAKAGLLPGTAVYIGEHPPQPTQVTIHIYDKKNYKRLDSFDTRQVKEAYEAGHNIWIDISGLADIEKITKIC
SEYNIHPLVIEDLLNTRQRPKLDIVDDYIFVVFKLLQSPPDHLSYNTEQFCLIIKQKLLLTFRESEKYNLSSIYQRLNGE
HSLTREYGSDYLTYLIMDYIVDDYFNFVETSAQLLETLEDQLINKPETIRLQALYTIKRRTITLRKIIPPLRDIVHLLLT
DDGGLINKKYNLYFRDLYDHCIRLVESIDLHREMSASMLDIYLSTINNRMNESMKILTLFASIFIPLSFIAGVYGMNFKF
MPELDWRYGYPMILVTMVLLAILMLYFFKRKKLF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=74, Percent_Identity=37.8378378378378, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41586; Mature: 41586

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHKTKASAKAGLLPGTAVYIGEHPPQPTQVTIHIYDKKNYKRLDSFDTRQVKEAYEAG
CCCCCCCHHHCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHCCCHHHHHHHHHHCC
HNIWIDISGLADIEKITKICSEYNIHPLVIEDLLNTRQRPKLDIVDDYIFVVFKLLQSPP
CEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
DHLSYNTEQFCLIIKQKLLLTFRESEKYNLSSIYQRLNGEHSLTREYGSDYLTYLIMDYI
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDDYFNFVETSAQLLETLEDQLINKPETIRLQALYTIKRRTITLRKIIPPLRDIVHLLLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DDGGLINKKYNLYFRDLYDHCIRLVESIDLHREMSASMLDIYLSTINNRMNESMKILTLF
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIFIPLSFIAGVYGMNFKFMPELDWRYGYPMILVTMVLLAILMLYFFKRKKLF
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTHKTKASAKAGLLPGTAVYIGEHPPQPTQVTIHIYDKKNYKRLDSFDTRQVKEAYEAG
CCCCCCCHHHCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHCCCHHHHHHHHHHCC
HNIWIDISGLADIEKITKICSEYNIHPLVIEDLLNTRQRPKLDIVDDYIFVVFKLLQSPP
CEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
DHLSYNTEQFCLIIKQKLLLTFRESEKYNLSSIYQRLNGEHSLTREYGSDYLTYLIMDYI
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDDYFNFVETSAQLLETLEDQLINKPETIRLQALYTIKRRTITLRKIIPPLRDIVHLLLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DDGGLINKKYNLYFRDLYDHCIRLVESIDLHREMSASMLDIYLSTINNRMNESMKILTLF
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIFIPLSFIAGVYGMNFKFMPELDWRYGYPMILVTMVLLAILMLYFFKRKKLF
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]