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The map label for this gene is 52843060

Identifier: 52843060

GI number: 52843060

Start: 3241975

End: 3242469

Strand: Direct

Name: 52843060

Synonym: lpg2865

Alternate gene names: NA

Gene position: 3241975-3242469 (Clockwise)

Preceding gene: 52843059

Following gene: 52843061

Centisome position: 95.42

GC content: 35.35

Gene sequence:

>495_bases
ATGAAAAAATATCTGACTACTGTGGAATTACAGAAAGAATCCATGAAGTTTTCTGCCGGGCATACCACCATCTTTTCGGC
AACAGAAAGAGAGCCTTTGCATGGTCATATGTATTCTGTTTATTTGGCTCTAACTACCTGGGTAGAAGAAAATGGTATGA
CTTTTGATTACCGTTATTACAAAGAGCGGATTCATAAATTATGCCGCTACTTAAATCAAACTTTTCTTATGCCACAATTT
TCACCTTTTTTAGAATACTCGGAAGATGAAGAATATTATTATTTCATCTTCAATAAGAAAAAAATCCCTTTTCTTAAAGA
AGATATCACCTTAATGCCCTTAACCAATATTACCGTGGAAGAGTTATCACGCTGGTTTGTTAATGAACTGATTAAAGAAA
AAGAGGAGTTAGATAATCATCGTATCGAAAAAGTAGTAGTCAAAGTGTTTTCCGCGCCCGGCCAATCAGCGAGTCATGAA
TGGCTTAGAAGTTAA

Upstream 100 bases:

>100_bases
GTGAAATGGGAGAGCTATTCAAAGTCATTGCGTTAACCAAAGATCTGGAAATTGATTTAAATGGTTTTCTGATAAATGAT
AAGAGAGTGAATTTATAATT

Downstream 100 bases:

>100_bases
ATGAACGATATTTATCAGGTTTGTATCCCCCATACCAATCGAGATTGTTTTGATTACGAAGCCCTGGATTTAACTCCATG
CATTGGCGGAAGAGTATGGG

Product: 6-pyruvoyl tetrahydropterin synthase, putative

Products: 6-pyruvoyl-5,6,7,8-tetrahydropterin; triphosphate

Alternate protein names: 6-Pyruvoyl Tetrahydropterin Synthase; 6-Pyruvoyl-Tetrahydropterin Synthase

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKKYLTTVELQKESMKFSAGHTTIFSATEREPLHGHMYSVYLALTTWVEENGMTFDYRYYKERIHKLCRYLNQTFLMPQF
SPFLEYSEDEEYYYFIFNKKKIPFLKEDITLMPLTNITVEELSRWFVNELIKEKEELDNHRIEKVVVKVFSAPGQSASHE
WLRS

Sequences:

>Translated_164_residues
MKKYLTTVELQKESMKFSAGHTTIFSATEREPLHGHMYSVYLALTTWVEENGMTFDYRYYKERIHKLCRYLNQTFLMPQF
SPFLEYSEDEEYYYFIFNKKKIPFLKEDITLMPLTNITVEELSRWFVNELIKEKEELDNHRIEKVVVKVFSAPGQSASHE
WLRS
>Mature_164_residues
MKKYLTTVELQKESMKFSAGHTTIFSATEREPLHGHMYSVYLALTTWVEENGMTFDYRYYKERIHKLCRYLNQTFLMPQF
SPFLEYSEDEEYYYFIFNKKKIPFLKEDITLMPLTNITVEELSRWFVNELIKEKEELDNHRIEKVVVKVFSAPGQSASHE
WLRS

Specific function: Unknown

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.3.12

Molecular weight: Translated: 19777; Mature: 19777

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYLTTVELQKESMKFSAGHTTIFSATEREPLHGHMYSVYLALTTWVEENGMTFDYRYY
CCCCHHHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHH
KERIHKLCRYLNQTFLMPQFSPFLEYSEDEEYYYFIFNKKKIPFLKEDITLMPLTNITVE
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHCCEEEEEECCCCHH
ELSRWFVNELIKEKEELDNHRIEKVVVKVFSAPGQSASHEWLRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC
>Mature Secondary Structure
MKKYLTTVELQKESMKFSAGHTTIFSATEREPLHGHMYSVYLALTTWVEENGMTFDYRYY
CCCCHHHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHH
KERIHKLCRYLNQTFLMPQFSPFLEYSEDEEYYYFIFNKKKIPFLKEDITLMPLTNITVE
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHCCEEEEEECCCCHH
ELSRWFVNELIKEKEELDNHRIEKVVVKVFSAPGQSASHEWLRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin

Specific reaction: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA