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The map label for this gene is glmS

Identifier: 52843032

GI number: 52843032

Start: 3209200

End: 3211014

Strand: Reverse

Name: glmS

Synonym: lpg2836

Alternate gene names: 52843032

Gene position: 3211014-3209200 (Counterclockwise)

Preceding gene: 52843033

Following gene: 52843031

Centisome position: 94.5

GC content: 40.83

Gene sequence:

>1815_bases
ATGTGCGGGATTATGGGAGCTGTTTCAGAACGGGATATTAGCAAGATTTTATTGGAAGGCTTGCGCCGATTGGAATATAG
AGGGTACGATTCTGCAGGTATTGCTGTCATAGATAGTCAAGATCGTTTAAAGAGAGTAAGAATCCAGGGGAAAGTGCAGA
ATTTGGCGGATGCTATGCAAGAGACCGCTATCGCTGGAAATACAGGTATAGCTCATACTCGTTGGGCGACGCATGGTAAA
CCCTCCGAACAAAATGCTCATCCTCATTTATCTCATGGAGAAATCGCATTAGTTCACAATGGCATTATTGAAAATCATGA
ACATTTGCGTCAACAACTTATTACTTATGGTTATCAATTCACATCTGAAACTGATACAGAGGTTGCTGCGCATTTAATTC
ATTATCATTACCAGCAGCATGAGAATTTATTACTTGCTGTACAAAAAGCTGCTGCAGAAATGCAAGGGGCTTTTGCATTA
GGAGTGATTCATCAGAAAAGACCAGAAGAATTGGTTGCAATTCGTAAAGGGAGTCCTTTGGTTTTGGGATTTGGAATTGG
TGAGAATTTCATTGCATCTGATGCCTTGGCACTCAGATCTTTCGCACAATCAGTTATTTACATGGAAGAGGGTGACAGTG
CTTGTGTCACAACACAGGATATTAAGGTCTATGATTCCAATCGAATACTTGTTCAAAGAGCGGTTCATCCGTTGAACAGT
GATTCTGAGATAGTGAATAAAGGGCCATACAGGCATTTTATGCTGAAAGAAATATTTGAACAATCGAAGGTAATCACAGA
CACGTTAGAAAGTCGAATTAATAGCATTGATGTGCTAAGAGCGAGTTTTGGTGAGAAAGCATCCCATATTTTCCCGGTGG
TAAAAAATATTCACATTGTGGCATGTGGAACCAGTTATCATGCTGGAATGATTGCCAAATATTGGCTTGAATCACTTGCC
GGCTTACCTACACAGGTTGAAATTGCAAGTGAATATCGATACCGAGATGTTGTTGTCCCCGACAATACCTTATTTATCAC
TGTATCTCAGTCAGGAGAAACAGCTGATACTCTTGCTGCCCTATTTAAGGCAAAGCAATCGAATTATTTGGCTAGTTTAG
CTATATGCAATGTTGCAACCAGTACTTTAGTGAGAGAGGCGGATTGTGTTTTTTTAACTCGGGCAGGTATTGAGATTGGT
GTAGCATCTACCAAAGCGTTTACTACACAGTTAGCAGCCTTCCTGATGTTGGCAGCAGCACTTTGTAAGGACAATCGTGC
GCAGGAAGTTTTAAGACAATTACAAGAGCTGCCTGCCTGTTGTGAGCGTGTTTTGCAGATGAATGAAGAAGTCGAATCAT
TGGCTTCTTTGTTTGTAAATAAAGTTCATGCCTTATTTTTAGGTCGAGGGGTTCAATATCCCGTAGCTCTGGAAGGCGCA
TTAAAACTTAAGGAAATATCTTATATACATGCGGAAGCTTATCCTGCCGGTGAATTAAAGCATGGTCCATTGGCTTTGGT
TGATAAGGATATGCCTGTGATTGCAGTAGCCCCTAATGATGAACTTTTAGATAAATTAAAATCCAATTTACATGAAGTGA
GTGCCAGAGGTGGGCAGTTATTTGTATTTGTTGATGATTCACAAAATTGGAAAGCGAATGGCGCTCGTTTAATCAAAGTT
CCATCCTGTGGTGCTTGGCTTGCGCCTATTGTTTACACTATTCCTTTGCAATTGCTGGCCTATCATGTTGCTGTAGCTAA
AGGGACTGATGTGGATCAACCTAGAAACCTTGCAAAATCGGTGACTGTAGAGTGA

Upstream 100 bases:

>100_bases
GCATTCTTATGCGTTTCACTCTTTATCTATATATAGTAGATGAACCAAGAATGAAAAAGCTTATTTCTACAAAAACAGTT
GCTGAAAAGAGGAGCAGGTT

Downstream 100 bases:

>100_bases
ACAAAGGTCAATATTTTTGGAATGAGTTATGGTGCGAGGGACGTATTTCTTTTCATAAAGAAGAAGTAAATCCGGATTTG
ATAGCCTATATCTCTTCCTT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MCGIMGAVSERDISKILLEGLRRLEYRGYDSAGIAVIDSQDRLKRVRIQGKVQNLADAMQETAIAGNTGIAHTRWATHGK
PSEQNAHPHLSHGEIALVHNGIIENHEHLRQQLITYGYQFTSETDTEVAAHLIHYHYQQHENLLLAVQKAAAEMQGAFAL
GVIHQKRPEELVAIRKGSPLVLGFGIGENFIASDALALRSFAQSVIYMEEGDSACVTTQDIKVYDSNRILVQRAVHPLNS
DSEIVNKGPYRHFMLKEIFEQSKVITDTLESRINSIDVLRASFGEKASHIFPVVKNIHIVACGTSYHAGMIAKYWLESLA
GLPTQVEIASEYRYRDVVVPDNTLFITVSQSGETADTLAALFKAKQSNYLASLAICNVATSTLVREADCVFLTRAGIEIG
VASTKAFTTQLAAFLMLAAALCKDNRAQEVLRQLQELPACCERVLQMNEEVESLASLFVNKVHALFLGRGVQYPVALEGA
LKLKEISYIHAEAYPAGELKHGPLALVDKDMPVIAVAPNDELLDKLKSNLHEVSARGGQLFVFVDDSQNWKANGARLIKV
PSCGAWLAPIVYTIPLQLLAYHVAVAKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_604_residues
MCGIMGAVSERDISKILLEGLRRLEYRGYDSAGIAVIDSQDRLKRVRIQGKVQNLADAMQETAIAGNTGIAHTRWATHGK
PSEQNAHPHLSHGEIALVHNGIIENHEHLRQQLITYGYQFTSETDTEVAAHLIHYHYQQHENLLLAVQKAAAEMQGAFAL
GVIHQKRPEELVAIRKGSPLVLGFGIGENFIASDALALRSFAQSVIYMEEGDSACVTTQDIKVYDSNRILVQRAVHPLNS
DSEIVNKGPYRHFMLKEIFEQSKVITDTLESRINSIDVLRASFGEKASHIFPVVKNIHIVACGTSYHAGMIAKYWLESLA
GLPTQVEIASEYRYRDVVVPDNTLFITVSQSGETADTLAALFKAKQSNYLASLAICNVATSTLVREADCVFLTRAGIEIG
VASTKAFTTQLAAFLMLAAALCKDNRAQEVLRQLQELPACCERVLQMNEEVESLASLFVNKVHALFLGRGVQYPVALEGA
LKLKEISYIHAEAYPAGELKHGPLALVDKDMPVIAVAPNDELLDKLKSNLHEVSARGGQLFVFVDDSQNWKANGARLIKV
PSCGAWLAPIVYTIPLQLLAYHVAVAKGTDVDQPRNLAKSVTVE
>Mature_604_residues
MCGIMGAVSERDISKILLEGLRRLEYRGYDSAGIAVIDSQDRLKRVRIQGKVQNLADAMQETAIAGNTGIAHTRWATHGK
PSEQNAHPHLSHGEIALVHNGIIENHEHLRQQLITYGYQFTSETDTEVAAHLIHYHYQQHENLLLAVQKAAAEMQGAFAL
GVIHQKRPEELVAIRKGSPLVLGFGIGENFIASDALALRSFAQSVIYMEEGDSACVTTQDIKVYDSNRILVQRAVHPLNS
DSEIVNKGPYRHFMLKEIFEQSKVITDTLESRINSIDVLRASFGEKASHIFPVVKNIHIVACGTSYHAGMIAKYWLESLA
GLPTQVEIASEYRYRDVVVPDNTLFITVSQSGETADTLAALFKAKQSNYLASLAICNVATSTLVREADCVFLTRAGIEIG
VASTKAFTTQLAAFLMLAAALCKDNRAQEVLRQLQELPACCERVLQMNEEVESLASLFVNKVHALFLGRGVQYPVALEGA
LKLKEISYIHAEAYPAGELKHGPLALVDKDMPVIAVAPNDELLDKLKSNLHEVSARGGQLFVFVDDSQNWKANGARLIKV
PSCGAWLAPIVYTIPLQLLAYHVAVAKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=38.1578947368421, Blast_Score=420, Evalue=1e-117,
Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=37.8102189781022, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI29570798, Length=202, Percent_Identity=28.2178217821782, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1790167, Length=610, Percent_Identity=56.8852459016394, Blast_Score=691, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=224, Percent_Identity=29.4642857142857, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082251, Length=313, Percent_Identity=22.3642172523962, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=715, Percent_Identity=34.6853146853147, Blast_Score=370, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17532899, Length=714, Percent_Identity=34.453781512605, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532897, Length=429, Percent_Identity=37.5291375291375, Blast_Score=265, Evalue=6e-71,
Organism=Saccharomyces cerevisiae, GI6322745, Length=445, Percent_Identity=37.9775280898876, Blast_Score=272, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6323731, Length=435, Percent_Identity=30.3448275862069, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=35.7843137254902, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323958, Length=166, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=37.0262390670554, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI28573187, Length=141, Percent_Identity=31.9148936170213, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24659598, Length=141, Percent_Identity=30.4964539007092, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66361; Mature: 66361

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIMGAVSERDISKILLEGLRRLEYRGYDSAGIAVIDSQDRLKRVRIQGKVQNLADAMQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
ETAIAGNTGIAHTRWATHGKPSEQNAHPHLSHGEIALVHNGIIENHEHLRQQLITYGYQF
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCEEE
TSETDTEVAAHLIHYHYQQHENLLLAVQKAAAEMQGAFALGVIHQKRPEELVAIRKGSPL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHHHCCCCCHHEEEECCCCE
VLGFGIGENFIASDALALRSFAQSVIYMEEGDSACVTTQDIKVYDSNRILVQRAVHPLNS
EEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCEEEECCCEEEEEHHCCCCCC
DSEIVNKGPYRHFMLKEIFEQSKVITDTLESRINSIDVLRASFGEKASHIFPVVKNIHIV
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEEEE
ACGTSYHAGMIAKYWLESLAGLPTQVEIASEYRYRDVVVPDNTLFITVSQSGETADTLAA
EECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCEEEEEEECCCCHHHHHHH
LFKAKQSNYLASLAICNVATSTLVREADCVFLTRAGIEIGVASTKAFTTQLAAFLMLAAA
HHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHH
LCKDNRAQEVLRQLQELPACCERVLQMNEEVESLASLFVNKVHALFLGRGVQYPVALEGA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVDKDMPVIAVAPNDELLDKLKSNLHEVSARGGQL
EEHHHHHEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEE
FVFVDDSQNWKANGARLIKVPSCGAWLAPIVYTIPLQLLAYHVAVAKGTDVDQPRNLAKS
EEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VTVE
CCCC
>Mature Secondary Structure
MCGIMGAVSERDISKILLEGLRRLEYRGYDSAGIAVIDSQDRLKRVRIQGKVQNLADAMQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
ETAIAGNTGIAHTRWATHGKPSEQNAHPHLSHGEIALVHNGIIENHEHLRQQLITYGYQF
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCEEE
TSETDTEVAAHLIHYHYQQHENLLLAVQKAAAEMQGAFALGVIHQKRPEELVAIRKGSPL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHHHCCCCCHHEEEECCCCE
VLGFGIGENFIASDALALRSFAQSVIYMEEGDSACVTTQDIKVYDSNRILVQRAVHPLNS
EEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCEEEECCCEEEEEHHCCCCCC
DSEIVNKGPYRHFMLKEIFEQSKVITDTLESRINSIDVLRASFGEKASHIFPVVKNIHIV
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEEEE
ACGTSYHAGMIAKYWLESLAGLPTQVEIASEYRYRDVVVPDNTLFITVSQSGETADTLAA
EECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCEEEEEEECCCCHHHHHHH
LFKAKQSNYLASLAICNVATSTLVREADCVFLTRAGIEIGVASTKAFTTQLAAFLMLAAA
HHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHH
LCKDNRAQEVLRQLQELPACCERVLQMNEEVESLASLFVNKVHALFLGRGVQYPVALEGA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVDKDMPVIAVAPNDELLDKLKSNLHEVSARGGQL
EEHHHHHEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEE
FVFVDDSQNWKANGARLIKVPSCGAWLAPIVYTIPLQLLAYHVAVAKGTDVDQPRNLAKS
EEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VTVE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA