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The map label for this gene is aroE

Identifier: 52843004

GI number: 52843004

Start: 3164142

End: 3164939

Strand: Reverse

Name: aroE

Synonym: lpg2808

Alternate gene names: 52843004

Gene position: 3164939-3164142 (Counterclockwise)

Preceding gene: 52843005

Following gene: 52843002

Centisome position: 93.15

GC content: 38.22

Gene sequence:

>798_bases
GTGCTTCGTCGTTTTGCAGTGATAGGTCATCCAATTGCACATAGTTTGTCTCCTGTCATTCATCAAATGTTTGCCCAACA
AACCCAAATTGAATTGATTTATGAAAAAATCTTGGGTGATGATGTCAAGTTTGAACAACAAATCTCTGATTTTTTTATCC
AGTATGGCAACGGGCTTAATGTCACTTTACCTTATAAAAAGCGCGCTTATGAATTAGCAAAAATACGCACGCAAAGATGC
ACCCTGGCTGGAGCAGCAAACACCCTATGGATGGAGGAAAATCAATTACATGCTGATAATACCGATGGTATTGGGTTGAT
ACGTGATTTATCCCGATTTCTTGAGTTAAAGGATAAAAAAATTCTGATTCTGGGGGCTGGCGGAGCTGCAAGAGGGATTA
TTTTTCCTTTATTGGAAGCGAAACCGTTACAATTAATTGTTGCTAATCGGACTTTGGAAAAAGCAGAAGAATTACAGCGT
CAATTTCCTCAAATCAATGTCACAAGTTTTGCTGAATTAACAGAATTCTTTGATTTAATCATCAATGCCACTTCTACGAG
TTTGTCCGGTCAGGTCATTGTATTACCTGAAGAGGTGTTATCCCATAAACCATTTTGTTATGATTTGGCTTATAATCAAA
AAACAAGCACCGCCTTTGTTCAATATGCTCGTAATGGAGGGTGCGAAGCAGTTGATGGATTAGGTATGTTAGTAGAGCAA
GCTGCGGAAGCATTCTTTACATGGAACAAAGTTATGCCTTCTACCCAAAAAATATTAGAACACCTGCGATCTTTTTAA

Upstream 100 bases:

>100_bases
CCGGGTGCGATTTAAGAACAACTTGGATTGATGTGCTTGTTGCGTGAGAACAGTTTATAATTAGGAAAACCAATGAAACC
TATAGGATAAAGGAGTTTTT

Downstream 100 bases:

>100_bases
ATTGGAAGCTTGCATAACAACTAGATGCACTTTGGCAACCAAACTCTGGTTAACTAAAAAAGGCGCTCACTTCTGTCGCT
GCAGTAATGGTGTCCTGGTA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLRRFAVIGHPIAHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKIRTQRC
TLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAEELQR
QFPQINVTSFAELTEFFDLIINATSTSLSGQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNGGCEAVDGLGMLVEQ
AAEAFFTWNKVMPSTQKILEHLRSF

Sequences:

>Translated_265_residues
MLRRFAVIGHPIAHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKIRTQRC
TLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAEELQR
QFPQINVTSFAELTEFFDLIINATSTSLSGQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNGGCEAVDGLGMLVEQ
AAEAFFTWNKVMPSTQKILEHLRSF
>Mature_265_residues
MLRRFAVIGHPIAHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKIRTQRC
TLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAEELQR
QFPQINVTSFAELTEFFDLIINATSTSLSGQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNGGCEAVDGLGMLVEQ
AAEAFFTWNKVMPSTQKILEHLRSF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=269, Percent_Identity=41.635687732342, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787983, Length=261, Percent_Identity=28.735632183908, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29851; Mature: 29851

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFAVIGHPIAHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLN
CCCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
VTLPYKKRAYELAKIRTQRCTLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKK
EEECCHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE
ILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAEELQRQFPQINVTSFAELTEFFDLI
EEEEECCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
INATSTSLSGQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNGGCEAVDGLGMLVEQ
HHCCCCCCCCEEEEECHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
AAEAFFTWNKVMPSTQKILEHLRSF
HHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLRRFAVIGHPIAHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLN
CCCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
VTLPYKKRAYELAKIRTQRCTLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKK
EEECCHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCE
ILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAEELQRQFPQINVTSFAELTEFFDLI
EEEEECCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
INATSTSLSGQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNGGCEAVDGLGMLVEQ
HHCCCCCCCCEEEEECHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
AAEAFFTWNKVMPSTQKILEHLRSF
HHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA