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The map label for this gene is nuoA

Identifier: 52842987

GI number: 52842987

Start: 3141237

End: 3141593

Strand: Reverse

Name: nuoA

Synonym: lpg2789

Alternate gene names: 52842987

Gene position: 3141593-3141237 (Counterclockwise)

Preceding gene: 52842988

Following gene: 52842986

Centisome position: 92.46

GC content: 39.22

Gene sequence:

>357_bases
ATGCTATCTCAATATCTACCCGTTCTCGTTTTTATAATTGTTGCCTTGATTTTAGGTGCAGTAATGATAGGCGCTGGTTC
TTTGCTTTCCAAGCATAGTCCGGATAGCGCTAAAAACTCCCCCTATGAGTGTGGTTTTGGCGCCTTTGAAAGCTCCCATA
TCCCGTTTGATGTACGGTTTTATCTGGTGGCTATTTTATTTATTATTTTTGATCTGGAAACAGCATTCTTTTTTCCTTGG
GCCTTGGCATTACGTAAAATAGGATGGTTTGGCTTTTATGCTATGATGTTATTTCTTGGACTGTTGGTTATAGGTTTTAT
TTATGAATGGAAAAGAGGCGCCCTAGAGTGGGAATAA

Upstream 100 bases:

>100_bases
GTGAAATTGGTAGACACGCCGTCTTGAGGGGGCGGTGGCGCAAGCCGTGCCGGTTCGAGTCCGGCCTTCGGCACCATTTT
AAATCGAGCAAGGTGAACTG

Downstream 100 bases:

>100_bases
GGTTCTTTCATTCTTTTAAAATATTTGATTTAATCTTTCATTTTAGCCATTACTATGGGAAGCAAAGGACGCTTGGCAAA
TCATTACAGAGCTTTTTGCT

Product: NADH dehydrogenase I, A subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MLSQYLPVLVFIIVALILGAVMIGAGSLLSKHSPDSAKNSPYECGFGAFESSHIPFDVRFYLVAILFIIFDLETAFFFPW
ALALRKIGWFGFYAMMLFLGLLVIGFIYEWKRGALEWE

Sequences:

>Translated_118_residues
MLSQYLPVLVFIIVALILGAVMIGAGSLLSKHSPDSAKNSPYECGFGAFESSHIPFDVRFYLVAILFIIFDLETAFFFPW
ALALRKIGWFGFYAMMLFLGLLVIGFIYEWKRGALEWE
>Mature_118_residues
MLSQYLPVLVFIIVALILGAVMIGAGSLLSKHSPDSAKNSPYECGFGAFESSHIPFDVRFYLVAILFIIFDLETAFFFPW
ALALRKIGWFGFYAMMLFLGLLVIGFIYEWKRGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=36.1111111111111, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13383; Mature: 13383

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSQYLPVLVFIIVALILGAVMIGAGSLLSKHSPDSAKNSPYECGFGAFESSHIPFDVRF
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
YLVAILFIIFDLETAFFFPWALALRKIGWFGFYAMMLFLGLLVIGFIYEWKRGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSQYLPVLVFIIVALILGAVMIGAGSLLSKHSPDSAKNSPYECGFGAFESSHIPFDVRF
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
YLVAILFIIFDLETAFFFPWALALRKIGWFGFYAMMLFLGLLVIGFIYEWKRGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA