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The map label for this gene is nuoH

Identifier: 52842980

GI number: 52842980

Start: 3133296

End: 3134318

Strand: Reverse

Name: nuoH

Synonym: lpg2782

Alternate gene names: 52842980

Gene position: 3134318-3133296 (Counterclockwise)

Preceding gene: 52842981

Following gene: 52842979

Centisome position: 92.25

GC content: 41.15

Gene sequence:

>1023_bases
ATGCTTCATACTATTGGCATACTAATTTGGATTATTATTAAAATTCTTGTGATAGTTGTCCCTTTACTGATTTCCGTGGC
CTACCTAACCTATGCGGAGCGTAAAGTGATTGGCTATATTCAAGTGCGTATCGGCCCGAACAGGGTTGGTTTAAAGGGCT
TGCTACAGCCATTTGCTGATTTATTGAAATTAATAACTAAAGAAATCATAGTTCCCACTCGATCAAATAAATACCTTTTT
GTTATTGCTCCACTTTTTGCTTTAGTCCCCTCCTTAGTCGGTTGGGCGGTAATCCCTTTTCAGGAAGGTATTGTCCTGGC
AAATATTAACGCAGGGGTCTTATACTTATTTGCCATGAGTTCGTTGGGCGTATATGGTGTTCTTATTGCAGGATGGGCAT
CGAATTCCAAATATGCCATGTTTGGCGCACTGCGTAGTACTGCCCAAACAGTCTCTTACGAAATTGCTATGGGATTTGCT
CTTGTTGGTGTGCTCTTGGCCGCTGGAAGCATGAACTTGACTGATATTGTTAATTCTCAAAAAGGTGGAATGCTGCATTG
GTGGTTTATTCCCTTGCTCCCCCTATTCTTGGTTTTCTGGATCTCCGGTATTGCAGAAACTAACAGAGCTCCTTTTGACT
TGGCAGAAGGTGAATCAGAAATTGTTGCTGGCTTCCATGTAGAATATTCTGGCATTGGATTCGCTTTATTCTTTCTCTCT
GAATACGCCAGTATGATTTTGATTTCAACAGTTTTGGCTATTTTATTCATGGGCGGATGGCTGTCACCTTTTGAAGGCAT
TACGTTCCTGGATCAAATCTTTTTTATAGTACCCGGATTTGTTTGGTTGCTTCTGAAAATTAGTTTCTTCCTTTTTGTGT
ATTTGTGGGTAAGGGCTACTTTCCCCCGATATCGTTATGACCAGCTTATGCGTTTAGGCTGGAAGGTACTTATCCCTGTT
ACTATAGTTTGGTTAATAGTAACCGCCCTTATGGTGGTTGCTCATGTCAAGCCATGGTTTTGA

Upstream 100 bases:

>100_bases
TGCGGTTGATGTTGTGTGGGTGGCAAATGCAATGCCAGAAACAGTTGACCTTGGTCACTCGTTTGCTGCAATAACAATAA
AGCGCTAGAAAGGTATAAAA

Downstream 100 bases:

>100_bases
CGGTTAGAAGAGAAGCCGATGAAAAAAGTATATCATTATATAATTCACTATGTTCGTACCTACTTACTGTTAGAGCTATT
AGCCGGTTTATGGTTAACAG

Product: NADH dehydrogenase I, H subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGIVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTALMVVAHVKPWF

Sequences:

>Translated_340_residues
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGIVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTALMVVAHVKPWF
>Mature_340_residues
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGIVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTALMVVAHVKPWF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=320, Percent_Identity=42.5, Blast_Score=244, Evalue=1e-64,
Organism=Escherichia coli, GI1788618, Length=330, Percent_Identity=43.3333333333333, Blast_Score=280, Evalue=9e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37996; Mature: 37996

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LLKLITKEIIVPTRSNKYLFVIAPLFALVPSLVGWAVIPFQEGIVLANINAGVLYLFAMS
HHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCEEEEEECCCEEEEECCCHHHHHHHHH
SLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFALVGVLLAAGSMNLTDIVNSQ
HCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
KGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHH
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPRYRYDQLMRLGWKVLIPVTIVWLIVTALMVVAHVKPWF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LLKLITKEIIVPTRSNKYLFVIAPLFALVPSLVGWAVIPFQEGIVLANINAGVLYLFAMS
HHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCEEEEEECCCEEEEECCCHHHHHHHHH
SLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFALVGVLLAAGSMNLTDIVNSQ
HCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
KGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHH
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPRYRYDQLMRLGWKVLIPVTIVWLIVTALMVVAHVKPWF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA