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The map label for this gene is cqsS [H]

Identifier: 52842938

GI number: 52842938

Start: 3084000

End: 3085289

Strand: Reverse

Name: cqsS [H]

Synonym: lpg2734

Alternate gene names: 52842938

Gene position: 3085289-3084000 (Counterclockwise)

Preceding gene: 52842943

Following gene: 52842936

Centisome position: 90.8

GC content: 34.73

Gene sequence:

>1290_bases
ATGTCACAACTAAAAAAAATAGTGAAACATTTAGATGAATCAATGCAGCGTAGTTTGTCTAATTCTGCTCATCAATTGGT
TGCAGTAGGCGCGATAGCTTTTGTGGGATTTCCTTTATTTTATGTTATTTGGGCTTTCTGGTTGCCTCAGCCTTATGAAA
ACCTGCCACTCCGTCTTATTGGAAGCCTTTTAGGTTTGGGATTGATGCTTACTCCTTATTGGCCATTAAAATGGAAGCAA
TATTTATCTTGGTATTGGTTTTTAACTCTTTTGTTTACTTTGCCATATTTTTTTACTTTTTTATTTTTAATGAATCAAGC
AAGCGTTATTTCTGCGATGTCTTTGTTGTGTGGTGTATTTTTACTTGTATTGCTCGTTGATTTATTGAGTTTATCCATTG
TGTTGATACTGGGGTTTAGTTTAGCCCTTGTAAGTTATTATCTTGTTTCTCCGCAAATGTATTTTGGAGAAGAGCATATA
CAAATGACATTGGTGATCATATTTACCATTATTGCAGGTTCTACTTTAAATTATAAAACAGCCATGTTGCAACAACAAAA
ATTGGCTGGCATGGCTGCTGCTGCAGGCATGATTGCCCATGAATTGCGTTCACCATTGTTAGGAATAAAGAGCGGCGCTC
AAGCTTTAGTCCAATATTTGCCAAGATTGATTGATGGTTACCAATTGGCTAAAAAACAAGAGTTAATATCCTCACCTTTA
CGTGACAGATTGTTATTACAGCTTGGGGGAGTCAGCAATCGAATTGTTAGTGAAATTGATTATGCTAATACGATCATTGA
TATGTTATTAGTCAAGGCAAGTCGCGATAATATTTTGCAAAATTGCATATTAGAGACTTGTTCTATAGCAGAATGTTTGT
CTGAGGCTATTACCAGATACCCATTTCAGTCACCAAGAGAAAGAACATTAATCACATGGACTGGTGATTTTCAATTTAAA
GGCTCTAAGTTGTTAATGCAGCATATTTTATTTAATTTAATAAAAAATGCACTTTATGTTATCGCAATGGCACAGCGTGG
GGAGATTAATATTTGGACTGAATCTGGCGATAAGTATCATTATTTGTATTTTAAAGACACAGCAAAAGGGATGAGCAAAC
AACAATTAAATCGATTATTTAATCATTTCTATACTACTACCTTTATGGGAACAGGCATTGGTTTATCATTTTGTAAATTA
GTTATGAATGCGTTTGGTGGTGATATTGTTTGTGAATCTAAAGAGGGCGAATACGCTTTGTTTATACTGAGTTTTCCAGG
CTCGGTTTAA

Upstream 100 bases:

>100_bases
GCATATCCCATGCACAATCCCTATATTTTATGATAGGCTTTTCTGGTAGATAAAGCGCTGAAAATCAGGGGCGTTTTTTA
GCTGGATTTAAGGATAAGAA

Downstream 100 bases:

>100_bases
AATTGGTTTTCTGTTGAACATACCATCATTCGTCTTAAAAGACGTAAGGATGGTATTGAGTTAGAGAGCTCCTGTGATTC
TCTTCTGCTAGAGTTTGGCC

Product: sensor protein LuxN

Products: NA

Alternate protein names: Cholerae quorum-sensing sensor [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSQLKKIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLIGSLLGLGLMLTPYWPLKWKQ
YLSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVFLLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHI
QMTLVIIFTIIAGSTLNYKTAMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPL
RDRLLLQLGGVSNRIVSEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRYPFQSPRERTLITWTGDFQFK
GSKLLMQHILFNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQQLNRLFNHFYTTTFMGTGIGLSFCKL
VMNAFGGDIVCESKEGEYALFILSFPGSV

Sequences:

>Translated_429_residues
MSQLKKIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLIGSLLGLGLMLTPYWPLKWKQ
YLSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVFLLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHI
QMTLVIIFTIIAGSTLNYKTAMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPL
RDRLLLQLGGVSNRIVSEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRYPFQSPRERTLITWTGDFQFK
GSKLLMQHILFNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQQLNRLFNHFYTTTFMGTGIGLSFCKL
VMNAFGGDIVCESKEGEYALFILSFPGSV
>Mature_428_residues
SQLKKIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLIGSLLGLGLMLTPYWPLKWKQY
LSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVFLLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHIQ
MTLVIIFTIIAGSTLNYKTAMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPLR
DRLLLQLGGVSNRIVSEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRYPFQSPRERTLITWTGDFQFKG
SKLLMQHILFNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQQLNRLFNHFYTTTFMGTGIGLSFCKLV
MNAFGGDIVCESKEGEYALFILSFPGSV

Specific function: Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to luxU and luxO [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48511; Mature: 48380

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEECCCCC
>Mature Secondary Structure 
SQLKKIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
GSLLGLGLMLTPYWPLKWKQYLSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHIQMTLVIIFTIIAGSTLNYKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCHHH
AMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RDRLLLQLGGVSNRIVSEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFQSPRERTLITWTGDFQFKGSKLLMQHILFNLIKNALYVIAMAQRGEINIWTESGDKYH
CCCCCCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCEEE
YLYFKDTAKGMSKQQLNRLFNHFYTTTFMGTGIGLSFCKLVMNAFGGDIVCESKEGEYAL
EEEEECHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCEEE
FILSFPGSV
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA