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The map label for this gene is pacS [H]

Identifier: 52842897

GI number: 52842897

Start: 3041997

End: 3044540

Strand: Direct

Name: pacS [H]

Synonym: lpg2691

Alternate gene names: 52842897

Gene position: 3041997-3044540 (Clockwise)

Preceding gene: 52842895

Following gene: 52842898

Centisome position: 89.53

GC content: 39.54

Gene sequence:

>2544_bases
ATGTCCAAGCCTTATTTTTTTTATGTCAGCGGAATGAATTGCACCAGTTGCAGTAATGCCATAGAGTCCTTTTTAAGAAA
TTCCAATTTAATCAAAATCAATACATTTCATGCAGACATGAGCACCCCAGACCCCAAAAAAATTGTGATATCTCTTTCTG
AAGAAAGAGAAAATGAACATGAAAGCAACTGGAAAATCATTAAAAAACTAATTGATGACACAGGGTTTACTTGTGAAAAC
CATGAATTCCCTCCAATTAAAGATGAGAAACCTACTCTCCTCCCCGAGAAAAAACAGACAGCAGCTCAACAAGAAGCCAG
CACATTATCCACAATATTTAGCAGCGCAAAAAAAATAATCACTTCCCATTGGTTGCTTGGAGGGCTAGGTTGTGTCACTG
GTGCTAGCTTAATGATCCTGACGATGGCTATAGGCGGTTTACCTCTTGCTGTAATGATTCCCCTAGCGGGTCTCAGCATT
TTATTAACCATTGCGCTTGGTGCCCAATCTTATTACGAGGCTTGGAAAAAGTTAGTCCAATCTCGCACACTCACAATGGA
CACATTGTTTTCAATTAGCACTGTTTCTGTTCTTATTGTGTCGCTTGCTTCATTCTTTGTACCGTGGTTACCTATGATGT
TTGAGGCAGGATTACTTATTTATGGATTCAGGCATATTGGTATCGCTATTGAGGACACTATCAAAGACAAAATAAGCTCA
ACCAAGTTTCAAGACAGAACCCCACAAAAAGTCAGATTATATCGCCATTCTGATTTTAAAAAAACGAGGATTGAAGAAAT
TCAACCCAATGACATTATACAAGTGAAACCAGGTGAGCTTATACCATTGGATAGCGTTTGTGAGCAAGACACCCTCATTT
ATCCCACCATCATTACCGGTGCTGTCATACCTAAACAATTTCGTAGTGGTGAAAAAATACTTGCCGGAATGCGTCTGGCA
AATGATGCAAAACCACTCACCCTCCGCGTTCTAAAAACTGCAAAAGAGTCATACCTTGCCCGTCTTGATGAAAGCATAGC
TCAATCTGTACTTGAAAAGGCACCGATAGAGATAAAAACAGGGCAGCTTCTTAGCTATTTTATCCCATCCATTATTGCTC
TCTCCATCCTTTCAGGGATCATTGTCGGCTTGATTGCTACACCAGCACTTGCGATACAATGCGCTATTTCAGTATTGGTT
TCTGCTTGCCCTTGTACTCTTGGTTTAATTATTCCTCTAGCAGTAAAAACTGGAATTCATAAAGGAGCCGAACACGGTGT
GCAGTTTAAAAATTCCAGGGTATTACAATTAGCAGAACAAATTGATGTAGTCATTTTTGACTTGAATGGCACTTTAACAA
CCGGCGTTCCTGTGGTTAAAGAATATGCGGTATTAAATGATGCCGATCTTTCTTCTGAGCATTTTCTGAGTATTTGCAAT
GTATTGGAGGGGCAATCAAAACATCCTTTCGGAAAAGCAATACAATCGTTTACTCAAGGAATCAATAAACAAAAATTCAA
TATTGCTAATTTGGATCATTCAAACCATTCAGGCATTTCAGCAGAGATTAATGGTATTCAATATACTATTGGCAGTAAAA
CCTTAATGCAGGAAATAGGGATTTCTACATCTTCGCTTGAAAACCAAATGAATCTGGTTGCGGGCGATAGCCTGGTATTT
CTAGCCAGAAACAAACAACTATTAGGTTATCTGGTCATCACCGACCCCTTACGAAAAGATGCAAAGCAAACAGTTGATGC
ATTAATTAAAATGGGAAAAGAAGTGCATCTATGCACTGGTGCAGATGAAAAAACCGCCTATCGCTATGCGCAAGCTCTTG
GCATTAAGAAAGTACATGCTAATTGTGTCGCTACAACTATCAATACAGAAGATAGATCCAAACCAGTTTATATTAAATCA
TTACAAAATCAGGGACTAAAAGTAGCTATGATTGGAGATGCGGCTAATGACGCAAACGCTCTTGCTGCGAGCGACTTCGG
TATAGCAGTACTGTCTCAAGACAGCGATGAAATCACCCAGCAACACGCCTCAGCCATTATACAAAGTGGAACTATATTGC
CTATAGCCAATGCCTTTGCCATATCAAAACAAACAGTAAACAATATCAACCAGAATTTGTTAATTAGCTTAGGGTACAAT
TTGACAACAGTATTAATAGCCGGCGGTCTGCTAGTCGCCCTTGGTTTTGCGCTAAACCCTGCTATTGGTGTGGCATTAAT
GGTAACCCAGGCTTGTTTTGTCTTGCTCAATGTATACCGCTTTAAAGAGCAACCCTTGCAACATTTGCAAGACAAAGTTC
AGGAAAAACCAGAACCGGCTCCTTCTTCTTATGAGGCCATGAAAAAGCATTCACCCAATTTCCATACAGCTCCCGAGATT
AATCATAAACCAGCCATTCAATCTGGAAAGCAGCCGACCAATAAAAATAAATCACCTTCCTTTTGGAGTGATTATTTTCC
TGAATTATTTGAGGAAGAAAAGGACACAAGCACCGAACACCTAATGAATAACAAAATAGGATAA

Upstream 100 bases:

>100_bases
CTGGCATTAAAATGCAATTTTTGCTCGATGGTTGGTGTTGATTGATAAATCCGGTACAAAGTTCTCAGGATGAGTTAACC
ATTTAACTCAGCGAGCGATT

Downstream 100 bases:

>100_bases
GCCCTAAATAAAGCTTGGCTGAATTTGAAATGAGGAAGGCCAATCACCTTCCTCAATCATAACAATCAATTTTGATTTAT
TATGCTCTAAAGGATCAAGA

Product: cation transporting ATPase PacS

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 847; Mature: 846

Protein sequence:

>847_residues
MSKPYFFYVSGMNCTSCSNAIESFLRNSNLIKINTFHADMSTPDPKKIVISLSEERENEHESNWKIIKKLIDDTGFTCEN
HEFPPIKDEKPTLLPEKKQTAAQQEASTLSTIFSSAKKIITSHWLLGGLGCVTGASLMILTMAIGGLPLAVMIPLAGLSI
LLTIALGAQSYYEAWKKLVQSRTLTMDTLFSISTVSVLIVSLASFFVPWLPMMFEAGLLIYGFRHIGIAIEDTIKDKISS
TKFQDRTPQKVRLYRHSDFKKTRIEEIQPNDIIQVKPGELIPLDSVCEQDTLIYPTIITGAVIPKQFRSGEKILAGMRLA
NDAKPLTLRVLKTAKESYLARLDESIAQSVLEKAPIEIKTGQLLSYFIPSIIALSILSGIIVGLIATPALAIQCAISVLV
SACPCTLGLIIPLAVKTGIHKGAEHGVQFKNSRVLQLAEQIDVVIFDLNGTLTTGVPVVKEYAVLNDADLSSEHFLSICN
VLEGQSKHPFGKAIQSFTQGINKQKFNIANLDHSNHSGISAEINGIQYTIGSKTLMQEIGISTSSLENQMNLVAGDSLVF
LARNKQLLGYLVITDPLRKDAKQTVDALIKMGKEVHLCTGADEKTAYRYAQALGIKKVHANCVATTINTEDRSKPVYIKS
LQNQGLKVAMIGDAANDANALAASDFGIAVLSQDSDEITQQHASAIIQSGTILPIANAFAISKQTVNNINQNLLISLGYN
LTTVLIAGGLLVALGFALNPAIGVALMVTQACFVLLNVYRFKEQPLQHLQDKVQEKPEPAPSSYEAMKKHSPNFHTAPEI
NHKPAIQSGKQPTNKNKSPSFWSDYFPELFEEEKDTSTEHLMNNKIG

Sequences:

>Translated_847_residues
MSKPYFFYVSGMNCTSCSNAIESFLRNSNLIKINTFHADMSTPDPKKIVISLSEERENEHESNWKIIKKLIDDTGFTCEN
HEFPPIKDEKPTLLPEKKQTAAQQEASTLSTIFSSAKKIITSHWLLGGLGCVTGASLMILTMAIGGLPLAVMIPLAGLSI
LLTIALGAQSYYEAWKKLVQSRTLTMDTLFSISTVSVLIVSLASFFVPWLPMMFEAGLLIYGFRHIGIAIEDTIKDKISS
TKFQDRTPQKVRLYRHSDFKKTRIEEIQPNDIIQVKPGELIPLDSVCEQDTLIYPTIITGAVIPKQFRSGEKILAGMRLA
NDAKPLTLRVLKTAKESYLARLDESIAQSVLEKAPIEIKTGQLLSYFIPSIIALSILSGIIVGLIATPALAIQCAISVLV
SACPCTLGLIIPLAVKTGIHKGAEHGVQFKNSRVLQLAEQIDVVIFDLNGTLTTGVPVVKEYAVLNDADLSSEHFLSICN
VLEGQSKHPFGKAIQSFTQGINKQKFNIANLDHSNHSGISAEINGIQYTIGSKTLMQEIGISTSSLENQMNLVAGDSLVF
LARNKQLLGYLVITDPLRKDAKQTVDALIKMGKEVHLCTGADEKTAYRYAQALGIKKVHANCVATTINTEDRSKPVYIKS
LQNQGLKVAMIGDAANDANALAASDFGIAVLSQDSDEITQQHASAIIQSGTILPIANAFAISKQTVNNINQNLLISLGYN
LTTVLIAGGLLVALGFALNPAIGVALMVTQACFVLLNVYRFKEQPLQHLQDKVQEKPEPAPSSYEAMKKHSPNFHTAPEI
NHKPAIQSGKQPTNKNKSPSFWSDYFPELFEEEKDTSTEHLMNNKIG
>Mature_846_residues
SKPYFFYVSGMNCTSCSNAIESFLRNSNLIKINTFHADMSTPDPKKIVISLSEERENEHESNWKIIKKLIDDTGFTCENH
EFPPIKDEKPTLLPEKKQTAAQQEASTLSTIFSSAKKIITSHWLLGGLGCVTGASLMILTMAIGGLPLAVMIPLAGLSIL
LTIALGAQSYYEAWKKLVQSRTLTMDTLFSISTVSVLIVSLASFFVPWLPMMFEAGLLIYGFRHIGIAIEDTIKDKISST
KFQDRTPQKVRLYRHSDFKKTRIEEIQPNDIIQVKPGELIPLDSVCEQDTLIYPTIITGAVIPKQFRSGEKILAGMRLAN
DAKPLTLRVLKTAKESYLARLDESIAQSVLEKAPIEIKTGQLLSYFIPSIIALSILSGIIVGLIATPALAIQCAISVLVS
ACPCTLGLIIPLAVKTGIHKGAEHGVQFKNSRVLQLAEQIDVVIFDLNGTLTTGVPVVKEYAVLNDADLSSEHFLSICNV
LEGQSKHPFGKAIQSFTQGINKQKFNIANLDHSNHSGISAEINGIQYTIGSKTLMQEIGISTSSLENQMNLVAGDSLVFL
ARNKQLLGYLVITDPLRKDAKQTVDALIKMGKEVHLCTGADEKTAYRYAQALGIKKVHANCVATTINTEDRSKPVYIKSL
QNQGLKVAMIGDAANDANALAASDFGIAVLSQDSDEITQQHASAIIQSGTILPIANAFAISKQTVNNINQNLLISLGYNL
TTVLIAGGLLVALGFALNPAIGVALMVTQACFVLLNVYRFKEQPLQHLQDKVQEKPEPAPSSYEAMKKHSPNFHTAPEIN
HKPAIQSGKQPTNKNKSPSFWSDYFPELFEEEKDTSTEHLMNNKIG

Specific function: May play a role in the osmotic adaptation [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=828, Percent_Identity=25.9661835748792, Blast_Score=219, Evalue=1e-56,
Organism=Homo sapiens, GI115529486, Length=687, Percent_Identity=27.3653566229985, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI55743073, Length=561, Percent_Identity=27.2727272727273, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI48762689, Length=211, Percent_Identity=29.8578199052133, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI48762691, Length=211, Percent_Identity=29.8578199052133, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1786691, Length=771, Percent_Identity=27.2373540856031, Blast_Score=232, Evalue=7e-62,
Organism=Escherichia coli, GI1789879, Length=744, Percent_Identity=23.9247311827957, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI1786914, Length=445, Percent_Identity=24.0449438202247, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17556548, Length=665, Percent_Identity=25.7142857142857, Blast_Score=174, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6320475, Length=639, Percent_Identity=30.5164319248826, Blast_Score=215, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6319772, Length=804, Percent_Identity=23.6318407960199, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI221329854, Length=590, Percent_Identity=24.0677966101695, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 92618; Mature: 92487

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPYFFYVSGMNCTSCSNAIESFLRNSNLIKINTFHADMSTPDPKKIVISLSEERENEH
CCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEEHHHCCCCH
ESNWKIIKKLIDDTGFTCENHEFPPIKDEKPTLLPEKKQTAAQQEASTLSTIFSSAKKII
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSHWLLGGLGCVTGASLMILTMAIGGLPLAVMIPLAGLSILLTIALGAQSYYEAWKKLVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SRTLTMDTLFSISTVSVLIVSLASFFVPWLPMMFEAGLLIYGFRHIGIAIEDTIKDKISS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHCEEEHHHHHHHHHC
TKFQDRTPQKVRLYRHSDFKKTRIEEIQPNDIIQVKPGELIPLDSVCEQDTLIYPTIITG
CCCCCCCCHHEEEEECCCCHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCEEEHHHHHH
AVIPKQFRSGEKILAGMRLANDAKPLTLRVLKTAKESYLARLDESIAQSVLEKAPIEIKT
HHCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GQLLSYFIPSIIALSILSGIIVGLIATPALAIQCAISVLVSACPCTLGLIIPLAVKTGIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGAEHGVQFKNSRVLQLAEQIDVVIFDLNGTLTTGVPVVKEYAVLNDADLSSEHFLSICN
CCHHCCCCCCCHHHHHHHHHCCEEEEECCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHH
VLEGQSKHPFGKAIQSFTQGINKQKFNIANLDHSNHSGISAEINGIQYTIGSKTLMQEIG
HHCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCEEEECCHHHHHHHHC
ISTSSLENQMNLVAGDSLVFLARNKQLLGYLVITDPLRKDAKQTVDALIKMGKEVHLCTG
CCHHHHHHHHHEEECCCEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHCCCEEEEECC
ADEKTAYRYAQALGIKKVHANCVATTINTEDRSKPVYIKSLQNQGLKVAMIGDAANDANA
CCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCC
LAASDFGIAVLSQDSDEITQQHASAIIQSGTILPIANAFAISKQTVNNINQNLLISLGYN
EEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCC
LTTVLIAGGLLVALGFALNPAIGVALMVTQACFVLLNVYRFKEQPLQHLQDKVQEKPEPA
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSSYEAMKKHSPNFHTAPEINHKPAIQSGKQPTNKNKSPSFWSDYFPELFEEEKDTSTEH
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LMNNKIG
HHHCCCC
>Mature Secondary Structure 
SKPYFFYVSGMNCTSCSNAIESFLRNSNLIKINTFHADMSTPDPKKIVISLSEERENEH
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEEHHHCCCCH
ESNWKIIKKLIDDTGFTCENHEFPPIKDEKPTLLPEKKQTAAQQEASTLSTIFSSAKKII
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSHWLLGGLGCVTGASLMILTMAIGGLPLAVMIPLAGLSILLTIALGAQSYYEAWKKLVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SRTLTMDTLFSISTVSVLIVSLASFFVPWLPMMFEAGLLIYGFRHIGIAIEDTIKDKISS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHCEEEHHHHHHHHHC
TKFQDRTPQKVRLYRHSDFKKTRIEEIQPNDIIQVKPGELIPLDSVCEQDTLIYPTIITG
CCCCCCCCHHEEEEECCCCHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCEEEHHHHHH
AVIPKQFRSGEKILAGMRLANDAKPLTLRVLKTAKESYLARLDESIAQSVLEKAPIEIKT
HHCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GQLLSYFIPSIIALSILSGIIVGLIATPALAIQCAISVLVSACPCTLGLIIPLAVKTGIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGAEHGVQFKNSRVLQLAEQIDVVIFDLNGTLTTGVPVVKEYAVLNDADLSSEHFLSICN
CCHHCCCCCCCHHHHHHHHHCCEEEEECCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHH
VLEGQSKHPFGKAIQSFTQGINKQKFNIANLDHSNHSGISAEINGIQYTIGSKTLMQEIG
HHCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCEEEECCHHHHHHHHC
ISTSSLENQMNLVAGDSLVFLARNKQLLGYLVITDPLRKDAKQTVDALIKMGKEVHLCTG
CCHHHHHHHHHEEECCCEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHCCCEEEEECC
ADEKTAYRYAQALGIKKVHANCVATTINTEDRSKPVYIKSLQNQGLKVAMIGDAANDANA
CCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCC
LAASDFGIAVLSQDSDEITQQHASAIIQSGTILPIANAFAISKQTVNNINQNLLISLGYN
EEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCC
LTTVLIAGGLLVALGFALNPAIGVALMVTQACFVLLNVYRFKEQPLQHLQDKVQEKPEPA
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSSYEAMKKHSPNFHTAPEINHKPAIQSGKQPTNKNKSPSFWSDYFPELFEEEKDTSTEH
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LMNNKIG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8370468 [H]